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  1. Research Article

    Feasibility of a multi-modal exercise program on cognition in older adults with Type 2 diabetes – a pilot randomised controlled trial

    Type 2 Diabetes (T2D) is associated with increased risk of dementia. We aimed to determine the feasibility of a randomised controlled trial (RCT) examining the efficacy of exercise on cognition and brain struc...

    M. L. Callisaya, R. M. Daly, J. E. Sharman, D. Bruce, T. M. E. Davis, T. Greenaway, M. Nolan, R. Beare, M. G. Schultz, T. Phan, L. C. Blizzard and V. K. Srikanth

    BMC Geriatrics 2017 17:237

    Published on: 16 October 2017

  2. Systematic Review

    Effectiveness and safety of dipeptidyl peptidase 4 inhibitors in the management of type 2 diabetes in older adults: a systematic review and development of recommendations to reduce inappropriate prescribing

    Preventable drug-related hospital admissions can be associated with drugs used in diabetes and the benefits of strict diabetes control may not outweigh the risks, especially in older populations. The aim of th...

    Gisela Schott, Yolanda V Martinez, R. Erandie Ediriweera de Silva, Anna Renom-Guiteras, Anna Vögele, David Reeves, Ilkka Kunnamo, Minna Marttila-Vaara and Andreas Sönnichsen

    BMC Geriatrics 2017 17(Suppl 1):226

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  3. Systematic Review

    Thiazides in the management of hypertension in older adults – a systematic review

    Thiazides are commonly prescribed to older people for the management of hypertension. The objective of this study was to identify the evidence on the risks and benefits of their use among adults aged ≥65 years...

    Christina Sommerauer, Neha Kaushik, Adrine Woodham, Anna Renom-Guiteras, Yolanda V Martinez, David Reeves, Ilkka Kunnamo, Thekraiat Al Qur‵an, Steffen Hübner and Andreas Sönnichsen

    BMC Geriatrics 2017 17(Suppl 1):228

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  4. Systematic Review

    Effectiveness and safety of vitamin K antagonists and new anticoagulants in the prevention of thromboembolism in atrial fibrillation in older adults – a systematic review of reviews and the development of recommendations to reduce inappropriate prescribing

    Oral anticoagulants are used for stroke prevention in patients with atrial fibrillation, the most common cardiac arrhythmia in older adults. The aim of our study was to identify the evidence on the risks and b...

    Christina Sommerauer, Lisa Schlender, Mark Krause, Sabine Weißbach, Anja Rieckert, Yolanda V Martinez, David Reeves, Anna Renom-Guiteras, Ilkka Kunnamo and Andreas Sönnichsen

    BMC Geriatrics 2017 17(Suppl 1):223

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  5. Study protocol

    A set of systematic reviews to help reduce inappropriate prescribing to older people: study protocol

    Multimorbidity and polypharmacy are common in older people. Assessment tools or lists of criteria aimed at supporting prescription decisions for older people exist, but have often been based on expert opinion ...

    Yolanda V. Martinez, Anna Renom-Guiteras, David Reeves, R. Erandie Ediriweera de Silva, Aneez Esmail, Ilkka Kunnamo, Anja Rieckert, Christina Sommerauer and Andreas Sönnichsen

    BMC Geriatrics 2017 17(Suppl 1):231

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  6. Systematic Review

    Effectiveness and safety of beta blockers in the management of hypertension in older adults: a systematic review to help reduce inappropriate prescribing

    The benefit from a blood pressure lowering therapy with beta blockers may not outweigh its risks, especially in older populations. The aim of this study was to look for evidence on risks and benefits of beta bloc...

    Anna Vögele, Tim Johansson, Anna Renom-Guiteras, David Reeves, Anja Rieckert, Lisa Schlender, Anne-Lisa Teichmann, Andreas Sönnichsen and Yolanda V Martinez

    BMC Geriatrics 2017 17(Suppl 1):224

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  7. Systematic Review

    Effectiveness and patient safety of platelet aggregation inhibitors in the prevention of cardiovascular disease and ischemic stroke in older adults – a systematic review

    Platelet aggregation inhibitors (PAI) are among the most frequently prescribed drugs in older people, though evidence about risks and benefits of their use in older adults is scarce. The objectives of this sys...

    Maren Meinshausen, Anja Rieckert, Anna Renom-Guiteras, Moritz Kröger, Christina Sommerauer, Ilkka Kunnamo, Yolanda V. Martinez, Aneez Esmail and Andreas Sönnichsen

    BMC Geriatrics 2017 17(Suppl 1):225

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  8. Systematic Review

    Efficacy and safety of metformin in the management of type 2 diabetes mellitus in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing

    Metformin is usually prescribed as first line therapy for type 2 diabetes mellitus (DM2). However, the benefits and risks of metformin may be different for older people. This systematic review examined the ava...

    Lisa Schlender, Yolanda V. Martinez, Charles Adeniji, David Reeves, Barbara Faller, Christina Sommerauer, Thekraiat Al Qur’an, Adrine Woodham, Ilkka Kunnamo, Andreas Sönnichsen and Anna Renom-Guiteras

    BMC Geriatrics 2017 17(Suppl 1):227

    Published on: 16 October 2017

    This article is part of a Supplement: Volume 17 Supplement 1

  9. Research article

    Low plasma tryptophan is associated with olfactory function in healthy elderly community dwellers in Japan

    Decreased circulating tryptophan (Trp) levels are frequently observed in elderly patients with neurodegenerative disease including Alzheimer’s disease. Trp may serve as a potential biomarker for monitoring dis...

    Yusuke Adachi, Yoshiki Shimodaira, Hidehiro Nakamura, Akira Imaizumi, Maiko Mori, Yoko Kageyama, Yasushi Noguchi, Asuka Seki, Yuki Okabe, Yuko Miyake, Kaori Ono and Shu Kumagai

    BMC Geriatrics 2017 17:239

    Published on: 16 October 2017

  10. Research Article

    Patient-centered professional practice models for managing low back pain in older adults: a pilot randomized controlled trial

    Low back pain is a debilitating condition for older adults, who may seek healthcare from multiple providers. Few studies have evaluated impacts of different healthcare delivery models on back pain outcomes in ...

    Christine M. Goertz, Stacie A. Salsbury, Cynthia R. Long, Robert D. Vining, Andrew A. Andresen, Maria A. Hondras, Kevin J. Lyons, Lisa Z. Killinger, Fredric D. Wolinsky and Robert B. Wallace

    BMC Geriatrics 2017 17:235

    Published on: 13 October 2017

  11. Research Article

    Association between traditional cardiovascular risk factors and mortality in the oldest old: untangling the role of frailty

    To date, there is no consensus regarding cardiovascular risk management in the very old. Studies have shown that the relationship between traditional cardiovascular risk factors and mortality is null or even i...

    Bert Vaes, David Depoortere, Gijs Van Pottelbergh, Catharina Matheï, Joana Neto and Jan Degryse

    BMC Geriatrics 2017 17:234

    Published on: 12 October 2017

  12. Research Article

    What is polypharmacy? A systematic review of definitions

    Multimorbidity and the associated use of multiple medicines (polypharmacy), is common in the older population. Despite this, there is no consensus definition for polypharmacy. A systematic review was conducted...

    Nashwa Masnoon, Sepehr Shakib, Lisa Kalisch-Ellett and Gillian E. Caughey

    BMC Geriatrics 2017 17:230

    Published on: 10 October 2017

  13. Research Article

    Positive and negative outcomes of informal caregiving at home and in institutionalised long-term care: a cross-sectional study

    Our ageing society is putting tremendous strain on public health and welfare programs to meet the needs of ageing individuals. Promoting informal caregiving is one way for policymakers to reduce this burden. H...

    Silke F. Metzelthin, Ellen Verbakel, Marja Y. Veenstra, Job van Exel, Antonius W. Ambergen and Gertrudis I. J. M. Kempen

    BMC Geriatrics 2017 17:232

    Published on: 10 October 2017

  14. Research Article

    Subjective health expectations of patients with age-related macular degeneration treated with antiVEGF drugs

    Subjective expectations regarding future health may influence patients’ judgement of current health and treatment effects, as well as adherence to therapies in chronic diseases. We aimed to explore subjective ...

    Márta Péntek, Valentin Brodszky, Zsolt Biró, Zsófia Kölkedi, Árpád Dunai, János Németh, Petra Baji, Fanni Rencz, László Gulácsi and Miklós D. Resch

    BMC Geriatrics 2017 17:233

    Published on: 10 October 2017

  15. Research Article

    Vitamin D deficiency was common among nursing home residents and associated with dementia: a cross sectional study of 545 Swedish nursing home residents

    Residents of nursing homes may have low 25-hydroxyvitamin D (25OHD) concentrations. Associations between vitamin D and cognitive performance, dementia and susceptibility to infections are not clearly establish...

    Rebeka Arnljots, Jörgen Thorn, Marie Elm, Michael Moore and Pär-Daniel Sundvall

    BMC Geriatrics 2017 17:229

    Published on: 10 October 2017

  16. Research Article

    Dying comfortably in very old age with or without dementia in different care settings – a representative “older old” population study

    Comfort is frequently ranked important for a good death. Although rising numbers of people are dying in very old age, many with dementia, little is known about symptom control for “older old” people or whether...

    Jane Fleming, Rowan Calloway, Anouk Perrels, Morag Farquhar, Stephen Barclay and Carol Brayne

    BMC Geriatrics 2017 17:222

    Published on: 5 October 2017

  17. Study protocol

    The rehabilitation enhancing aging through connected health (REACH) study: study protocol for a quasi-experimental clinical trial

    Mobility limitations among older adults increase the risk for disability and healthcare utilization. Rehabilitative care is identified as the most efficacious treatment for maintaining physical function. Howev...

    Meng Ni, Lorna G. Brown, Danielle Lawler, Terry D. Ellis, Tamara Deangelis, Nancy K. Latham, Jennifer Perloff, Steve J. Atlas, Sanja Percac-Lima and Jonathan F. Bean

    BMC Geriatrics 2017 17:221

    Published on: 20 September 2017

  18. Research Article

    Self-detection of atrial fibrillation in an aged population: three-year follow-up of the LietoAF intervention study

    Atrial fibrillation (AF) is often asymptomatic and undiagnosed until an ischaemic stroke occurs. An irregular pulse is a key manifestation of AF. We assessed whether pulse self-palpation is feasible in screeni...

    Jussi Jaakkola, Raine Virtanen, Tuija Vasankari, Marika Salminen and K.E. Juhani Airaksinen

    BMC Geriatrics 2017 17:218

    Published on: 16 September 2017

  19. Study protocol

    Informed decision-making with and for people with dementia – efficacy of the PRODECIDE education program for legal representatives: protocol of a randomized controlled trial (PRODECIDE-RCT)

    In Germany, the guardianship system provides adults who are no longer able to handle their own affairs a court-appointed legal representative, for support without restriction of legal capacity. Although these ...

    Julia Lühnen, Burkhard Haastert, Ingrid Mühlhauser and Tanja Richter

    BMC Geriatrics 2017 17:217

    Published on: 15 September 2017

  20. Research Article

    Prevalence of frailty and its associated factors in older hospitalised patients in Vietnam

    Frailty is an emerging issue in geriatrics and gerontology. The prevalence of frailty is increasing as the population ages. Like many developing countries, Vietnam has a rapidly ageing population. However, the...

    Huyen Thi Thanh Vu, Thanh Xuan Nguyen, Tu N. Nguyen, Anh Trung Nguyen, Robert Cumming, Sarah Hilmer and Thang Pham

    BMC Geriatrics 2017 17:216

    Published on: 15 September 2017

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