Articles

Pre-stroke cognitive impairment is associated with vascular imaging pathology: a prospective observational study

Chronic brain pathology and pre-stroke cognitive impairment (PCI) is predictive of post-stroke dementia. The aim of the current study was to measure pre-stroke neurodegenerative and vascular disease burden fou...

Authors: Till Schellhorn, Manuela Zucknick, Torunn Askim, Ragnhild Munthe-Kaas, Hege Ihle-Hansen, Yngve M. Seljeseth, Anne-Brita Knapskog, Halvor Næss, Hanne Ellekjær, Pernille Thingstad, Torgeir Bruun Wyller, Ingvild Saltvedt and Mona K. Beyer

High prevalence of osteoporosis in patients undergoing spine surgery in China

With the increase in life expectancy, a large number of patients with osteoporosis (OP) are undergoing spine surgery, which may adversely affect the surgical success rate. The prevalence of OP varies in differ...

Authors: Xiaoyi Mo, Shengli Zhao, Zhenxing Wen, Wei Lin, Zhipeng Chen, Zhiyun Wang, Chen Huang, Jie Qin, Jie Hao and Bailing Chen

Structural equation model of affecting factors on elder abuse to patients under hemodialysis by family caregivers

The objectives of the present study were to determine the prevalence of older adults with hemodialysis (HD) abuse by family caregivers and the factors affecting it.

Authors: Amaneh Mahmoudian, Abbas Shamsalinia, Atefeh Alipour, Zahra Fotoukian and Fatemeh Ghaffari

Is achieving 7,000 steps/day cross-sectionally and prospectively associated with older adults’ lower-extremity performance?

Evidence regarding the association between daily steps recommendation and older adults’ lower limb strength is lacking; thus, this study investigated whether taking at least 7,000 steps/day is cross-sectionall...

Authors: Ming-Chun Hsueh, Chien-Yu Lin, Ting-Fu Lai, Yi-Chien Yu, Shao-Hsi Chang, Ju Yong Bae and Yung Liao

Subjective and objective health predicting mortality and institutionalization: an 18-year population-based follow-up study among community-dwelling Finnish older adults

Objective health measures, such as registered illnesses or frailty, predict mortality and institutionalization in older adults. Also, self-reported assessment of health by simple self-rated health (SRH) has be...

Authors: Anna Viljanen, Marika Salminen, Kerttu Irjala, Elisa Heikkilä, Raimo Isoaho, Sirkka-Liisa Kivelä, Päivi Korhonen, Tero Vahlberg, Matti Viitanen, Maarit Wuorela, Minna Löppönen and Laura Viikari

Association between frailty and ischemic heart disease: a systematic review and meta-analysis

Frailty is increasingly reported among older adults with cardiovascular diseases and it has been demonstrated to increase negative health outcomes and mortality. To date, no systematic review of the evidence i...

Authors: Rosa Liperoti, Davide L. Vetrano, Katie Palmer, Tomasz Targowski, Maria C. Cipriani, Maria R. Lo Monaco, Silvia Giovannini, Nicola Acampora, Emanuele Rocco Villani, Roberto Bernabei and Graziano Onder

A mixed-methods study evaluating the impact of an excursion-based social group on quality of life of older adults

Social isolation is an increasing concern for older adults who live in the community. Despite some availability of social support programs to address social isolation, their effectiveness is not routinely meas...

Authors: Joyce Siette, Mikaela Jorgensen, Amy Nguyen, Gilbert Knaggs, Stuart Miller and Johanna I. Westbrook

The role of SARC-F scale in predicting progression risk of COVID-19 in elderly patients: a prospective cohort study in Wuhan

Since the outbreak of COVID-19, it has been documented that old age and underlying illnesses are associated with poor prognosis among COVID-19 patients. However, it is unknown whether sarcopenia, a common geri...

Authors: Yao Ma, Min He, Li-Sha Hou, Shen Xu, Zhi-Xin Huang, Na Zhao, Yan Kang, Ji-Rong Yue and Chenkai Wu

Association of life course socioeconomic status and adult height with cognitive functioning of older adults in India and China

Cognitive functioning is an important measure of intrinsic capacity. In this study, we examine the association of life course socioeconomic status (SES) and height with cognitive functioning among older adults...

Authors: Y. Selvamani and P. Arokiasamy

Psychometric validation of the Chinese version of the PaArticular Scales among elderly residents in long-term care facilities with joint contractures

Joint contractures, which affect activity, participation, and quality of life, are common complications of neurological conditions among elderly residents in long-term care facilities. This study examined the ...

Authors: Yi-chang Chen, Keh-chung Lin, Chen-Jung Chen, Shu-Hui Yeh, Ay-Woan Pan, Hao-Ling Chen and Chih-Hung Wang

Association between successful aging transitions and depressive symptoms among older Korean adults: findings from the Korean longitudinal study of aging (2006–2018)

The importance of SA (Successful aging) has been emphasized in recent years, with focus shifting towards attaining healthier aging rather than longevity. However, the influence of SA and its changes on mental ...

Authors: Fatima Nari, Bich Na Jang, Selin Kim, Wonjeong Jeong, Sung-In Jang and Eun-Cheol Park

Barriers and facilitators to the implementation of social robots for older adults and people with dementia: a scoping review

Psychosocial issues, such as social isolation and loneliness among older adults and people with dementia, continue to pose challenges with a rapidly aging population worldwide. Social robots are a rapidly emer...

Authors: Wei Qi Koh, Simone Anna Felding, Kübra Beliz Budak, Elaine Toomey and Dympna Casey

Fear of falling is as important as multiple previous falls in terms of limiting daily activities: a longitudinal study

Fear of falling and previous falls are both risk factors that affect daily activities of older adults. However, it remains unclear whether they independently limit daily activities accounting for each other.

Authors: Minhui Liu, Tianxue Hou, Yuxiao Li, Xiaocao Sun, Sarah L. Szanton, Lindy Clemson and Patricia M. Davidson

Frailty increases the risk for developing urinary tract infection among 79,887 patients with diabetic mellitus and chronic kidney disease

Patients with diabetic mellitus (DM) and chronic kidney disease (CKD) are at an increased risk of urinary tract infection (UTI) due to their altered immunological integrity. These patients are similarly prone ...

Authors: Chia-Ter Chao, Szu-Ying Lee, Jui Wang, Kuo-Liong Chien and Jenq-Wen Huang

A novel Longshi Scale measured activity of daily living disability in elderly patients affected by neurological diseases: a multi-center cross-sectional study in China

Ability in the activities of daily life is often impaired in the older adults with a neurological disease. The Barthel Index is an instrument used worldwide to assess such ability. The Longshi Scale is a pictu...

Authors: Jingpu Zhao, Xiangxiang Liu, Li Wan, Yan Gao, Meiling Huang, Fubing Zha, Jianjun Long, Dongxia Li, Guohui Nie and Yulong Wang

A stepped-wedge randomised controlled trial assessing the implementation, effectiveness and cost-consequences of the EDDIE+ hospital avoidance program in 12 residential aged care homes: study protocol

Older people living in residential aged care homes experience frequent emergency transfers to hospital. These events are associated with risks of hospital acquired complications and invasive treatments or inte...

Authors: Hannah E. Carter, Xing J. Lee, Alison Farrington, Carla Shield, Nicholas Graves, Elizabeth V. Cyarto, Lynne Parkinson, Florin I. Oprescu, Claudia Meyer, Jeffrey Rowland, Trudy Dwyer and Gillian Harvey

Contribution of IQ in young adulthood to the associations of education and occupation with cognitive ability in older age

Studies suggest that a higher education and occupation are each associated with a higher late-life cognitive ability, but their inter-relationships in their association with cognitive ability and the contribut...

Authors: Insa Feinkohl, Petra Kozma, Friedrich Borchers, Simone J. T. van Montfort, Jochen Kruppa, Georg Winterer, Claudia Spies and Tobias Pischon

Correction to: Factors associated with self-rated health in a Norwegian population of older people participating in a preventive home visit program: a cross-sectional study

Authors: Astrid Fjell, Berit Cronfalk Seiger, Monica Hermann, Arvid Rongve, Jörg Aßmus, Lars Kvinge, Åke Seiger, Knut Skaug and Anne-Marie Boström

Instruments used to assess quality of life of older adults in African countries: a scoping review

Over 60% of the population in sub-Saharan Africa, live in informal settlements (slums) with little or no resources. To be prepared to meet the needs of older people living in slums, it is necessary to know mor...

Authors: Priscilla Y. A. Attafuah, Irma H. J. Everink, Ruud J. G. Halfens, Christa Lohrmann, Aaron Abuosi and Jos M. G. A. Schols

Promoting neuroplasticity and neuropsychological functioning in frailty through an app-based sensorimotor training: study protocol for a randomized trial

Frailty is characterized by an age-related decline in multiple physiological systems, leading to a high vulnerability to stressors, adverse health outcomes, and low quality of life. Neuroscientific models of p...

Authors: Florian Beier, Martin Löffler, Frauke Nees, Lucrezia Hausner, Lutz Frölich and Herta Flor

Transitions between levels of dependency among older people receiving social care – a retrospective longitudinal cohort study in a Swedish municipality

Knowledge is scarce on how needs for home help and special housing evolve among older people who begin to receive support from municipal social care. The purpose of this study was to describe baseline distribu...

Authors: Magnus Zingmark and Fredrik Norström

Experiences of community-dwelling older people with dementia participating in a person-centred multidimensional interdisciplinary rehabilitation program

There is great need for development of feasible rehabilitation for older people with dementia. Increased understanding of this population’s experiences of rehabilitation participation is therefore important. T...

Authors: Anna Sondell, Josefine Lampinen, Mia Conradsson, Håkan Littbrand, Undis Englund, Ingeborg Nilsson and Nina Lindelöf

The sex difference in gait speed among older adults: how do sociodemographic, lifestyle, social and health determinants contribute?

This study explores whether a sex difference in sensitivity to (strength of the association) and/or in exposure to (prevalence) determinants of gait speed contributes to the observed lower gait speed among old...

Authors: Lena D. Sialino, Laura A. Schaap, Sandra H. van Oostrom, H. Susan J. Picavet, Johannes W.R. Twisk, W. M. Monique Verschuren, Marjolein Visser and Hanneke A.H. Wijnhoven

Sarcopenia as a predictor of mortality among the critically ill in an intensive care unit: a systematic review and meta-analysis

The evidence of sarcopenia based on CT-scan as an important prognostic factor for critically ill patients has not seen consistent results. To determine the impact of sarcopenia on mortality in critically ill p...

Authors: Xiao-Ming Zhang, Denghong Chen, Xiao-Hua Xie, Jun-E Zhang, Yingchun Zeng and Andy SK Cheng

A comparison of spouse and non-spouse carers of people with dementia: a descriptive analysis of Swedish national survey data

Being an informal carer of a person with dementia (PwD) can have a negative effect on the carer’s health and quality of life, and spouse carers have been found to be especially vulnerable. Yet relatively littl...

Authors: Marcus F. Johansson, Kevin J. McKee, Lena Dahlberg, Christine L. Williams, Martina Summer Meranius, Elizabeth Hanson, Lennart Magnusson, Björn Ekman and Lena Marmstål Hammar

Evaluation of the Psychometric Properties of PainChek® in UK Aged Care Residents with advanced dementia

The aim of this study was to further validate PainChek®, an electronic pain assessment instrument, with a population living with dementia in a UK care home.

Authors: Ivana Babicova, Ainslea Cross, Dawn Forman, Jeffery Hughes and Kreshnik Hoti

Validation of perceived physical fatigability using the simplified-Chinese version of the Pittsburgh Fatigability Scale

The Pittsburgh Fatigability Scale (PFS) was developed to capture fatigue and demand in a single tool, filling a gap that no validated questionnaire existed to measure perceived fatigability. Since fatigability...

Authors: Yixin Hu, Hangming Zhang, Weihao Xu, Ming Zhao, Juan Liu, Linna Wu, Lin Zou, Jing Zuo, Yunxia Liu, Li Fan, Woei-Nan Bair, Yujia (Susanna) Qiao and Nancy W. Glynn

Functional status and its associated factors among community-dwelling older adults in rural Nepal: findings from a cross-sectional study

The high burden of chronic conditions, coupled with various physical, mental, and psychosocial changes that accompany the phenomenon of aging, may limit the functional ability of older adults. This study aims ...

Authors: Saruna Ghimire, Grish Paudel, Sabuj Kanti Mistry, Mahmood Parvez, Binod Rayamajhee, Pravash Paudel, Man Kumar Tamang and Uday Narayan Yadav

Neutrophil-lymphocyte ratio as a predictor of delirium in older internal medicine patients: a prospective cohort study

Delirium is a common neuropsychiatric syndrome in older hospitalized patients. Previous studies have suggested that inflammation and oxidative stress contribute to the pathophysiology of delirium. However, it ...

Authors: Yanli Zhao, Jirong Yue, Peng Lei, Taiping Lin, Xuchao Peng, Dongmei Xie, Langli Gao, Xiaoyu Shu and Chenkai Wu

Association between hearing loss and frailty: a systematic review and meta-analysis

Frailty is associated with poor health outcomes in later life. Recent studies suggested that hearing loss may be a potentially modifiable risk factor associated with frailty.

Authors: Rong Tian, Osvaldo P. Almeida, Dona M. P. Jayakody and Andrew H. Ford

Optimal care for the management of older people non-weight bearing after lower limb fracture: a consensus study

Older people who are non-weight-bearing after a lower limb fracture are at risk of poor outcomes but there are no clinical guidelines for this group of patients. Given the paucity of the research evidence base...

Authors: S. Aloraibi, J. Gladman, D. Godfrey, V. Booth, K. Robinson, E. Lunt, A. Caswell, M. Kerr, B. Ollivere and A. L. Gordon

Type of tea consumption and depressive symptoms in Chinese older adults

Existing research indicates that tea drinking may exert beneficiary effects on mental health. However, associations between different types of tea intake and mental health such as depression have not been full...

Authors: Yao Yao, Huashuai Chen, Lele Chen, Sang-Yhun Ju, Huazhen Yang, Yi Zeng, Danan Gu and Tze Pin Ng

Soluble ST2 and risk of cognitive impairment after acute ischemic stroke: a prospective observational study

Soluble suppression of tumorigenesis-2 (sST2) was reported to be associated with cognitive performance and risk of incident stroke. However, the impact of sST2 on cognitive function after ischemic stroke is un...

Authors: Yinwei Zhu, Chongquan Fang, Qi Zhang, Yaling Lu, Rui Zhang, Aili Wang, Xiaoqing Bu, Jintao Zhang, Zhong Ju, Yonghong Zhang, Tan Xu and Chongke Zhong

Association between anemia, physical performance and cognitive function in Iranian elderly people: evidence from Bushehr Elderly Health (BEH) program

The present study aimed to investigate the relation between anemia and hemoglobin (Hgb) concentration, physical performance, and cognitive function in a large sample of Iranian elderly population.

Authors: Maryam Marzban, Iraj Nabipour, Akram Farhadi, Afshin Ostovar, Bagher Larijani, Amir Hossein Darabi, Elnaz Shabankari and Mohamad Gholizade

Serum sodium in relation to various domains of cognitive function in the elderly US population

Recent evidence suggests that sodium imbalances may be associated with cognitive impairment; however, the association between specific domains of cognition remains unclear. This study examines the association ...

Authors: Sohyae Lee, Jin-young Min, Beom Kim, Sang-Won Ha, Jeohng Ho Han and Kyoung-bok Min

Cost-utility analysis of a consensus and evidence-based medication review to optimize and potentially reduce psychotropic drug prescription in institutionalized dementia patients

Growing evidence shows the effects of psychotropic drugs on the evolution of dementia. Until now, only a few studies have evaluated the cost-effectiveness of psychotropic drugs in institutionalized dementia pa...

Authors: Mireia Massot Mesquida, Frans Folkvord, Gemma Seda, Francisco Lupiáñez-Villanueva and Pere Torán Monserrat

Multi-disciplinary supportive end of life care in long-term care: an integrative approach to improving end of life

Optimal supportive end of life care for frail, older adults in long term care (LTC) homes involves symptom management, family participation, advance care plans, and organizational support. This 2-phase study a...

Authors: Patricia M. Harasym, Misha Afzaal, Sarah Brisbin, Aynharan Sinnarajah, Lorraine Venturato, Patrick Quail, Sharon Kaasalainen, Sharon Straus, Tamara Sussman, Navjot Virk and Jayna M. Holroyd-Leduc

Development of an 360-degree virtual reality video-based immersive cycle training system for physical enhancement in older adults: a feasibility study

Recently, there is an increased number of studies that use 360° virtual reality (VR) video for medical and rehabilitative purposes. However, the 360° VR video experience for older adults has not yet been inves...

Authors: Namsu Lee, Wonjae Choi and Seungwon Lee

Self-help guided by trained lay providers for generalized anxiety disorder in older adults: study protocol for a randomized controlled trial

Only a small proportion of older patients with generalized anxiety disorder (GAD) seek professional help. Difficulties in accessing treatment may contribute to this problem. Guided self-help based on the princ...

Authors: Philippe Landreville, Patrick Gosselin, Sébastien Grenier and Pierre-Hugues Carmichael

Feasibility and preliminary effect of anabolic steroids in addition to strength training and nutritional supplement in rehabilitation of patients with hip fracture: a randomized controlled pilot trial (HIP-SAP1 trial)

Anabolic steroid has been suggested as a supplement during hip fracture rehabilitation and a Cochrane Review recommended further trials. The aim was to determine feasibility and preliminary effect of a 12-week...

Authors: Signe Hulsbæk, Thomas Bandholm, Ilija Ban, Nicolai Bang Foss, Jens-Erik Beck Jensen, Henrik Kehlet and Morten Tange Kristensen

Socio-economic inequality in the prevalence of violence against older adults – findings from India

Violence against older adults is a well-recognised socio-psychological and public health problem. It is uncared-for, undiagnosed, and an untreated problem that is widespread across both developed and developin...

Authors: Debashree Sinha, Prem Shankar Mishra, Shobhit Srivastava and Pradeep Kumar

Clinical features and outcomes of COVID-19 in older adults: a systematic review and meta-analysis

Few studies have focused on exploring the clinical characteristics and outcomes of COVID-19 in older patients. We conducted this systematic review and meta-analysis to have a better understanding of the clinic...

Authors: Sunny Singhal, Pramod Kumar, Sumitabh Singh, Srishti Saha and Aparajit Ballav Dey

A randomized clinical study on the impact of Comprehensive Geriatric Assessment (CGA) based interventions on the quality of life of elderly, frail, onco-hematologic patients candidate to anticancer therapy: protocol of the ONCO-Aging study

Age is considered as one of the most important risk-factor for many types of solid and hematological cancers, as their incidence increases with age in parallel to the ever-growing elderly population. Moreover,...

Authors: Abdurraouf Mokhtar Mahmoud, Federica Biello, Paola Maria Maggiora, Riccardo Bruna, Giovanni Burrafato, Miriam Cappelli, Feba Varughese, Veronica Martini, Francesca Platini, Clara Deambrogi, Andrea Patriarca, Maura Nicolosi, Ajay ram Vachanaram, Carla Pisani, Eleonora Ferrara, Elvira Catania…

Clinical characteristics and factors related to antibiotic-associated diarrhea in elderly patients with pneumonia: a retrospective cohort study

Antibiotic-associated diarrhea (AAD) is a common problem among elderly inpatients because many elderly patients are admitted for pneumonia or other conditions that necessitate antibiotic treatment. In the supe...

Authors: Yoko Takedani, Tsukasa Nakamura, Noriko Fukiwake, Toshihiro Imada, Junji Mashino and Takeshi Morimoto

Needs of older persons living in long-term care institutions: on the usefulness of cluster approach

Long-term care units’ residents do not constitute a homogeneous population. Providing effective care, tailored to individual needs, is crucial in this context. It can be facilitated by suitable tools and metho...

Authors: Sławomir Tobis, Krystyna Jaracz, Sylwia Kropińska, Dorota Talarska, Juanita Hoe, Katarzyna Wieczorowska-Tobis and Aleksandra Suwalska

Profile and needs of primary informal caregivers of older patients in Belgian geriatric day hospitals: a multicentric cross-sectional study

With the improvement of life expectancy, the world faces increasing demands for care of older persons. In this manuscript, we define the characteristics of primary informal caregivers (PIC) of patients aged 75...

Authors: C. Eyaloba, I. De Brauwer, S. Cès, F. Benoit, S. Gillain, L. Pesch, H. Rouvière and S. De Breucker

Singapore multidisciplinary consensus recommendations on muscle health in older adults: assessment and multimodal targeted intervention across the continuum of care

The rapidly aging societies worldwide and in Singapore present a unique challenge, requiring an integrated multidisciplinary approach to address high-value targets such as muscle health. We propose pragmatic e...

Authors: Samuel T. H. Chew, Geetha Kayambu, Charles Chin Han Lew, Tze Pin Ng, Fangyi Ong, Jonathan Tan, Ngiap Chuan Tan and Shuen-Loong Tham

Associations between nut intake, cognitive function and non‐alcoholic fatty liver disease (NAFLD) in older adults in the United States: NHANES 2011-14

Nuts are nutrient-rich and reported to provide some cognitive and cardiometabolic health benefits, but limited studies have focused on older adults. This study investigated the cross-sectional relationship bet...

Authors: Sze-Yen Tan, Ekavi N. Georgousopoulou, Barbara R. Cardoso, Robin M. Daly and Elena S. George

Ambient bright light treatment improved proxy-rated sleep but not sleep measured by actigraphy in nursing home patients with dementia: a placebo-controlled randomised trial

Up to 70% of nursing home patients with dementia suffer from sleep problems. Light is the main zeitgeber to the circadian system and thus has a fundamental impact on sleep-wake behaviour. Low indoor light leve...

Authors: Gunnhild J. Hjetland, Eirin Kolberg, Ståle Pallesen, Eirunn Thun, Inger Hilde Nordhus, Bjørn Bjorvatn and Elisabeth Flo-Groeneboom

A web-based dynamic Nomogram for predicting instrumental activities of daily living disability in older adults: a nationally representative survey in China

Instrumental Activities of Daily Living (IADL) disability is a common health burden in aging populations. The identification of high-risk individuals is essential for timely targeted interventions. Although pr...

Authors: Li Zhang, Huijie Cui, Qiuzhi Chen, Yan Li, Chunxia Yang and Yanfang Yang