NIH Consensus Statement: Osteoporosis prevention, diagnosis, and therapy. JAMA. 2001, 285: 785-795. 10.1001/jama.285.6.785.
Article
Google Scholar
Herrmann M, Schmidt JP, Umanskaya N, Wagner A, Taban-Shomal O, Widmann T, Colaianni G, Wildemann B, Herrmann W: The role of hyperhomocysteinemia as well as folate, vitamin B(6) and B(12) deficiencies in osteoporosis: a systematic review. Clin Chem Lab Med. 2007, 45: 1621-1632.
CAS
PubMed
Google Scholar
Melton LJ: Adverse outcomes of osteoporotic fractures in the general population. J Bone Miner Res. 2003, 18: 1139-1141. 10.1359/jbmr.2003.18.6.1139.
Article
PubMed
Google Scholar
Lippuner K, Golder M, Greiner R: Epidemiology and direct medical costs of osteoporotic fractures in men and women in Switzerland. Osteoporos Int. 2005, 16 (Suppl 2): S8-S17.
Article
PubMed
Google Scholar
Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A: Incidence and economic burden of osteoporosis-related fractures in the United States, 2005–2025. J Bone Miner Res. 2007, 22: 465-475. 10.1359/jbmr.061113.
Article
PubMed
Google Scholar
Raisz LG: Homocysteine and osteoporotic fractures–culprit or bystander?. N Engl J Med. 2004, 350: 2089-2090. 10.1056/NEJMe048030.
Article
CAS
PubMed
Google Scholar
Dhonukshe-Rutten RA, Pluijm SM, de Groot LC, Lips P, Smit JH, van Staveren WA: Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people. J Bone Miner Res. 2005, 20: 921-929. 10.1359/JBMR.050202.
Article
CAS
PubMed
Google Scholar
Herrmann M, Widmann T, Herrmann W: Homocysteine - a newly recognised risk factor for osteoporosis. Clin Chem Lab Med. 2005, 43: 1111-1117.
CAS
PubMed
Google Scholar
van Meurs JB, Dhonukshe-Rutten RA, Pluijm SM, Pluijm SMF, van der Klift M, de Jonge R, Lindemans J, de Groot LCPGM, Hofman A, Witterman JCM, van Leeuwen JPTM, Breteler MMB, Lips P, Pols HAP, Uitterlinden AG: Homocysteine levels and the risk of osteoporotic fracture. N Engl J Med. 2004, 350: 2033-2041. 10.1056/NEJMoa032546.
Article
CAS
PubMed
Google Scholar
McLean RR, Jacques PF, Selhub J, Tucker KL, Samelson EJ, Broe KE, Hannan MT, Cupples LA, Kiel DP: Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med. 2004, 350: 2042-2049. 10.1056/NEJMoa032739.
Article
CAS
PubMed
Google Scholar
Gjesdal CG, Vollset SE, Ueland PM, Refsum H, Meyer HE, Tell GS: Plasma homocysteine, folate, and vitamin B 12 and the risk of hip fracture: the hordaland homocysteine study. J Bone Miner Res. 2007, 22: 747-756. 10.1359/jbmr.070210.
Article
CAS
PubMed
Google Scholar
Levasseur R: Bone tissue and hyperhomocysteinemia. Joint Bone Spine. 2009, 76: 234-240. 10.1016/j.jbspin.2008.11.002.
Article
CAS
PubMed
Google Scholar
McLean RR, Jacques PF, Selhub J, Fredman L, Tucker KL, Samelson EJ, Kiel DP, Cupples LA, Hannan MT: Plasma B vitamins, homocysteine, and their relation with bone loss and hip fracture in elderly men and women. J Clin Endocrinol Metab. 2008, 93: 2206-2212. 10.1210/jc.2007-2710.
Article
CAS
PubMed
PubMed Central
Google Scholar
Gerdhem P, Ivaska KK, Isaksson A, Pettersson K, Vaananen HK, Obrant KJ, Akesson K: Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women. J Bone Miner Res. 2007, 22: 127-134.
Article
CAS
PubMed
Google Scholar
Stanger O, Herrmann W, Pietrzik K, Fowler B, Geisel J, Dierkes J, Weger M: DACH-LIGA homocystein (german, austrian and swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B-vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med. 2003, 41: 1392-1403.
CAS
PubMed
Google Scholar
Homocysteine Trialists Collaboration: Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials. Am J Clin Nutr. 2005, 82: 806-812.
Google Scholar
Green TJ, McMahon JA, Skeaff CM, Williams SM, Whiting SJ: Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial. Am J Clin Nutr. 2007, 85: 460-464.
CAS
PubMed
Google Scholar
Herrmann M, Stanger O, Paulweber B, Hufnagl C, Herrmann W: Folate supplementation does not affect biochemical markers of bone turnover. Clin Lab. 2006, 52: 131-136.
CAS
PubMed
Google Scholar
Herrmann M, Umanskaya N, Traber L, Schmidt-Gayk H, Menke W, Lanzer G, Lenhart M, Schmidt JP, Herrmann W: The effect of B-vitamins on biochemical bone turnover markers and bone mineral density in osteoporotic patients: a 1-year double blind placebo controlled trial. Clin Chem Lab Med. 2007, 45: 1785-1792.
CAS
PubMed
Google Scholar
Keser I, Ilich JZ, Vrkic N, Giljevic Z, Colic Baric I: Folic acid and vitamin B12 supplementation lowers plasma homocysteine but has no effect on serum bone turnover markers in elderly women: a randomized, double-blind, placebo-controlled trial. Nutr Res. 2013, 33: 211-219. 10.1016/j.nutres.2013.01.002.
Article
CAS
PubMed
Google Scholar
Sawka AM, Ray JG, Yi Q, Josse RG, Lonn E: Randomized clinical trial of homocysteine level lowering therapy and fractures. Arch Intern Med. 2007, 167: 2136-2139. 10.1001/archinte.167.19.2136.
Article
CAS
PubMed
Google Scholar
Lonn E, Yusuf S, Arnold MJ, Sheridan P, Pogue J, Micks M, McQueen MJ, Probstfield J, Fodor G, Held C, Genest J: Homocysteine lowering with folic acid and B vitamins in vascular disease. N Engl J Med. 2006, 354: 1567-1577.
Article
CAS
PubMed
Google Scholar
Sato Y, Honda Y, Iwamoto J, Kanoko T, Satoh K: Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial. JAMA. 2005, 293: 1082-1088. 10.1001/jama.293.9.1082.
Article
CAS
PubMed
Google Scholar
van Meurs JB, Uitterlinden AG: Homocysteine and fracture prevention. JAMA. 2005, 293: 1121-1122. 10.1001/jama.293.9.1121.
Article
CAS
PubMed
Google Scholar
VITATOPS Trial Study Group: The VITATOPS (Vitamins to Prevent Stroke) Trial: rationale and design of an international, large, simple, randomised trial of homocysteine-lowering multivitamin therapy in patients with recent transient ischaemic attack or stroke. Cerebrovasc Dis. 2002, 13: 120-126.
Article
Google Scholar
VITATOPS Trial Study Group: B vitamins in patients with recent transient ischaemic attack or stroke in the VITAmins TO Prevent Stroke (VITATOPS) trial: a randomised, double-blind, parallel, placebo-controlled trial. Lancet Neurol. 2010, 9: 855-865.
Article
Google Scholar
Hippisley-Cox J, Coupland C: Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFractureScores. BMJ. 2009, 339: b4229-10.1136/bmj.b4229.
Article
PubMed
PubMed Central
Google Scholar
Moayyeri A, Alrawi YA, Myint PK: The complex mutual connection between stroke and bone health. Arch Biochem Biophys. 2010, 503: 153-159. 10.1016/j.abb.2010.06.023.
Article
CAS
PubMed
Google Scholar
Sandercock P: Vitamin B supplements for prevention of stroke. Lancet Neurol. 2010, 9: 842-843. 10.1016/S1474-4422(10)70188-5.
Article
PubMed
Google Scholar
van Wijngaarden JP, Dhonukshe-Rutten RA, van Schoor NM, van der Velde N, Swart KM, Enneman AW, van Dijk SC, Bouwer-Brolsma EM, Zillikens MC, van Meurs JB, Brug J, Uitterlinden AG, Lips P, de Groot LC: Rationale and design of the B-PROOF study, a randomized controlled trial on the effect of supplemental intake of vitamin B12 and folic acid on fracture incidence. BMC Geriatr. 2011, 11: 80-10.1186/1471-2318-11-80.
Article
CAS
PubMed
PubMed Central
Google Scholar