Articles

Systematic review and meta-analysis of second-generation antidepressants for the treatment of older adults with depression: questionable benefit and considerations for frailty

Frail older adults are commonly prescribed antidepressants. Yet, there is little evidence to determine the efficacy and safety of antidepressants to treat depression with concomitant frailty. To better underst...

Authors: Laurie Mallery, Tanya MacLeod, Michael Allen, Pamela McLean-Veysey, Natasha Rodney-Cail, Evan Bezanson, Brian Steeves, Constance LeBlanc and Paige Moorhouse

Association between anemia and cognitive decline among Chinese middle-aged and elderly: evidence from the China health and retirement longitudinal study

Our objective was to characterize the relationship of anemia and hemoglobin concentrations with cross-sectional cognitive functions and changes in cognitive functions over 2 years in a large sample of Chinese ...

Authors: Tingting Qin, Mingming Yan, Zhen Fu, Yating Song, Wanrong Lu, A’dan Fu and Ping Yin

Knowledge of HIV/AIDS among older adults (50 years and above) in a peri-urban setting: a descriptive cross-sectional study

In the absence of vaccine or cure, public knowledge about Human Immune Virus (HIV) is a central tool for curbing HIV epidemic. This study sought to assess the knowledge of HIV among older adults (50 years and ...

Authors: Reindolf Anokye, Enoch Acheampong, Amy Budu-Ainooson, Edmund Isaac Obeng, Emmanuel Tetteh, Yvonne Sabby Acheampong and Curtis Edward Nettey-Marbell

Fall-related emergency department visits and hospitalizations among community-dwelling older adults: examination of health problems and injury characteristics

Fall injuries and related healthcare use among older adults are increasing in the United States. This study examined chronic illnesses, sensory and memory problems, and injury characteristics that were associa...

Authors: Namkee G. Choi, Bryan Y. Choi, Diana M. DiNitto, C. Nathan Marti and Mark E. Kunik

Cross-sectional associations between personality traits and device-based measures of step count and sedentary behaviour in older age: the Lothian Birth Cohort 1936

While the associations between personality traits and self-reported physical activity are well replicated, few studies have examined the associations between personality and device-based measures of both physi...

Authors: Iva Čukić, Catharine R. Gale, Sebastien F. M. Chastin, Philippa M. Dall, Manon L. Dontje, Dawn A. Skelton and Ian J. Deary

The value of nonoperative versus operative treatment of frail institutionalized elderly patients with a proximal femoral fracture in the shade of life (FRAIL-HIP); protocol for a multicenter observational cohort study

Proximal femoral fractures are strongly associated with morbidity and mortality in elderly patients. Mortality is highest among frail institutionalized elderly with both physical and cognitive comorbidities wh...

Authors: Pieter Joosse, Sverre A. I. Loggers, C. L. P. (Marc) Van de Ree, Romke Van Balen, Jeroen Steens, Rutger G. Zuurmond, Taco Gosens, Sven H. Van Helden, Suzanne Polinder, Hanna C. Willems and Esther M. M. Van Lieshout

In-hospital care prior to assisted and unassisted suicide in swiss older people: a state-level retrospective study

Authors: Nathalie Dieudonné-Rahm, Sandra Burkhardt and Sophie Pautex

Advanced glycation end products and their ratio to soluble receptor are associated with limitations in physical functioning only in women: results from the CARLA cohort

Advanced glycation end products (AGEs), modifications of proteins or amino acids, are increasingly produced and accumulated with age-related diseases. Recent studies suggested that the ratio of AGEs and their ...

Authors: Helen Ebert, Maria Elena Lacruz, Alexander Kluttig, Andreas Simm, Karin Halina Greiser, Daniel Tiller, Nadja Kartschmit and Rafael Mikolajczyk

Associations between health-related quality of life, physical function and pain in older women with osteoporosis and vertebral fracture

Osteoporosis and vertebral fractures represent a major health burden worldwide, and the prevalence of osteoporosis is expected to increase as the world’s population ages. Suffering from vertebral fracture has ...

Authors: Brita Stanghelle, Hege Bentzen, Lora Giangregorio, Are Hugo Pripp and Astrid Bergland

Determinants of ADL and IADL disability in older adults in southeastern Poland

The extension of the life span has led to an increase in the number of older people and an increase in the prevalence of disability in people over 60 years of age. The aim of this study was to assess the preva...

Authors: Agnieszka Ćwirlej-Sozańska, Agnieszka Wiśniowska-Szurlej, Anna Wilmowska-Pietruszyńska and Bernard Sozański

Accessing the discriminatory performance of FRAIL-NH in two-class and three-class frailty and examining its agreement with the frailty index among nursing home residents in mainland China

FRAIL-NH has been commonly used to assess frailty in nursing home residents and validated in many ethnic populations; however, it has not been validated in mainland China, where such an assessment tool is lack...

Authors: Feng Ge, Weiwei Liu, Minhui Liu, Siyuan Tang, Yongjin Lu and Tianxue Hou

Balancing the struggle to live with dementia: a systematic meta-synthesis of coping

People with dementia describe experiences of loss that threaten their autonomy and ability to contribute to society. They often have difficulties with orientation, loss of roll function, and fear about the fut...

Authors: Guro Hanevold Bjørkløf, Anne-Sofie Helvik, Tanja Louise Ibsen, Elisabeth Wiken Telenius, Ellen Karine Grov and Siren Eriksen

Interactions between subjective memory complaint and objective cognitive deficit on memory performances

Subjective memory complaint (SMCs) is a common trait amongst older population. The subjective cognition about their memory could depend on objective cognition. The aim of the current study was to examine the i...

Authors: Soowon Park, Ji-Hye Lee, Jiyeon Lee, Youngsung Cho, Hyun Gyu Park, Yongjoon Yoo, Jung-Hae Youn, Seung-Ho Ryu, Jae Yeon Hwang, Jeongsim Kim and Jun-Young Lee

Exploring the implementation of the Community for Successful Ageing (ComSA)program in Singapore: lessons learnt on program delivery for improving BioPsychoSocial health

The Community for Successful Ageing (ComSA) program has implemented overlapping BioPsychoSocial (BPS) components as part of a Community Development (CD) grassroots and volunteer-led initiative. Implementation ...

Authors: Su Aw, Gerald C. H. Koh, Chuen Seng Tan, Mee Lian Wong, Hubertus J. M. Vrijhoef, Susana Concordo Harding, Mary Ann B. Geronimo and Zoe J. L. Hildon

Fall-related efficacy is a useful and independent index to detect fall risk in Japanese community-dwelling older people: a 1-year longitudinal study

Fall-related efficacy has been found to be associated with both falls and fall risk factors such as physical performance. The aim of the present study was to clarify whether fall-related efficacy is, independe...

Authors: Naoto Kamide, Yoshitaka Shiba, Miki Sakamoto, Haruhiko Sato and Akie Kawamura

Resident and staff perspectives of person-centered climate in nursing homes: a cross-sectional study

Person-centered care is widely recognized as a gold standard and is based on a supportive psychosocial climate for both residents and staff in nursing homes. Residents and staff may have different perspectives...

Authors: Yunxia Yang, Hui Li, Lily Dongxia XIAO, Wenhui Zhang, Menghan Xia and Hui Feng

Antibiotics prescription and guidelines adherence in elderly: impact of the comorbidities

Although the interest of antibiotics is well known, antibiotics prescription is associated with side effect, especially in patients with multiples comorbidities. One way to reduce the incidence of side effects...

Authors: Anthony Dylis, Anne Sophie Boureau, Audrey Coutant, Eric Batard, François Javaudin, Gilles Berrut, Laure de Decker and Guillaume Chapelet

Adherence to anti-osteoporosis medication associated with lower mortality following hip fracture in older adults: a nationwide propensity score-matched cohort study

We investigated the association of anti-osteoporosis medication with mortality risk in older adults with hip fractures and evaluated the influence of medication adherence on mortality.

Authors: Shan-Fu Yu, Jur-Shan Cheng, Ying-Chou Chen, Jia-Feng Chen, Chung-Yuan Hsu, Han-Ming Lai, Chi-Hua Ko, Wen-Chan Chiu, Yu-Jih Su and Tien-Tsai Cheng

Impact of a delirium prevention project among older hospitalized patients who underwent orthopedic surgery: a retrospective cohort study

Postoperative delirium (POD) is a common clinical syndrome with significant negative outcomes. Thus, we aimed to evaluate the feasibility and effectiveness of a delirium screening tool and multidisciplinary de...

Authors: Jung-Yeon Choi, Kwang-il Kim, Min-gu Kang, Young-Kyun Lee, Kyung-Hoi Koo, Joo Han Oh, Young Ho Park, Jeewon Suh, Nak-Hyun Kim, Hyun-Jung Yoo, Jahyun Koo, Hyun Mi Moon, Eun Hui Kim, Kayoung Park and Cheol-Ho Kim

Scaling-up implementation in community hospitals: a multisite interrupted time series design of the Mobilization of Vulnerable Elders (MOVE) program in Alberta

As the population ages, older hospitalized patients are at increased risk for hospital-acquired morbidity. The Mobilization of Vulnerable Elders (MOVE) program is an evidence-informed early mobilization interv...

Authors: Jayna Holroyd-Leduc, Charmalee Harris, Jemila S. Hamid, Joycelyne E. Ewusie, Jacquelyn Quirk, Karen Osiowy, Julia E. Moore, Sobia Khan, Barbara Liu and Sharon E. Straus

Age-related deficits in bilateral motor synergies and force coordination

Ageing may cause impairments in executing bilateral movement control. This study investigated age-related changes in interlimb force coordination across multiple trials by quantifying bilateral motor synergies...

Authors: Nyeonju Kang, Lisa M. Roberts, Clara Aziz and James H. Cauraugh

Transitioning of older Australian women into and through the long-term care system: a cohort study using linked data

Over two-thirds of older Australians use different types/levels of aged care at some point in later life. Our aims were to estimate transitional probabilities and to identify risk factors influencing the movem...

Authors: Md. Mijanur Rahman, Jimmy T. Efird and Julie E. Byles

The impact of early comprehensive geriatric screening on the readmission rate in an acute geriatric ward: a quasi-experimental study

Unplanned readmission is an important healthcare quality issue. We studied the effect of a comprehensive geriatric screen (CGS) in the early admission course followed by a comprehensive geriatric assessment on...

Authors: Kun-Pei Lin, Jen-Hau Chen, Feng-Ping Lu, Chiung-Jung Wen and Ding-Cheng (Derrick) Chan

Texture modified diet in German nursing homes: availability, best practices and association with nursing home characteristics

For nursing home (NH) residents with swallowing or chewing problems, appealing texture-modified-diets (TMD) need to be available in order to support adequate nutrition. The aim of this study was to describe th...

Authors: Carina Burger, Eva Kiesswetter, Rowena Alber, Ulrike Pfannes, Ulrike Arens-Azevedo and Dorothee Volkert

Prevalence and determinants of frailty in the absence of disability among older population: a cross sectional study from rural communities in Nepal

Longevity and frailty have significant implications for healthcare delivery. They increase demands for healthcare service and surge risk of hospitalization. Despite gaining global attention, determinants of fr...

Authors: Uday Narayan Yadav, Man Kumar Tamang, Tarka Bahadur Thapa, Hassan Hosseinzadeh, Mark Fort Harris and Krishna Kumar Yadav

‘Modified STOPP-START criteria for Sri Lanka’; translating to a resource limited healthcare setting by Delphi consensus

‘Screening tool of older people’s prescriptions (STOPP) and screening tool to alert to right treatment (START)’ criteria is a useful tool to assess the appropriateness of medicines among older adults. However,...

Authors: N. R. Samaranayake, A. Balasuriya, G. H. Fernando, D. Samaraweera, L. G. T. Shanika, J. K. P. Wanigasuriya, C. N. Wijekoon and C. A. Wanigatunge

Psychometric properties of the geriatric quality of life-dementia in older adults with dementia or mild cognitive impairment living in nursing homes

Given the theoretical and methodological limitations, there is insufficient knowledge about the psychometric properties and internal structure of quality of life (QOL) measurements for patients with dementia l...

Authors: Eun-Young Park, Seon-Min Park and Jung-Hee Kim

“What would you like to achieve?” Goal-Setting in Patients with Dementia in Geriatric Rehabilitation

Setting meaningful, individualized rehabilitation goals is an essential part of the rehabilitation process. Even though patients with dementia are a drastically increasing patient group in geriatric rehabilita...

Authors: Ilona Dutzi, Michael Schwenk, Marietta Kirchner, Jürgen M. Bauer and Klaus Hauer

Peer-to-peer support model to improve quality of life among highly vulnerable, low-income older adults in Cape Town, South Africa

Developing countries are experiencing rapid population ageing. Many do not have the resources or formal structures available to support the health and wellbeing of people as they age. In other contexts, the us...

Authors: Leon N. Geffen, Gabrielle Kelly, John N. Morris and Elizabeth P. Howard

Bridging the gap between research-based knowledge and clinical practice: a qualitative examination of patients and physiotherapists’ views on the Otago exercise Programme

Falls and fall-related injuries exacerbate the health problems of older adults, and they are a public health concern. Despite an abundance of research, the implementation of evidence-based fall prevention prog...

Authors: Hilde Worum, Daniela Lillekroken, Birgitte Ahlsen, Kirsti Skavberg Roaldsen and Astrid Bergland

Polypharmacy in older patients: identifying the need for support by a community pharmacist

The community pharmacist is a key player in medication reviews of older outpatients. However, it is not always clear which individuals require a medication review. The objective of the present study was to ide...

Authors: Jean-Baptiste Beuscart, Ségolène Petit, Sophie Gautier, Patrick Wierre, Thibaut Balcaen, Jean-Marc Lefebvre, Nicolas Kambia, Elisabeth Bertoux, Daniel Mascaut, Christine Barthélémy, Damien Cuny, François Puisieux and Bertrand Décaudin

Anticholinergic and benzodiazepine medication use and risk of incident dementia: a UK cohort study

Studies suggest that anticholinergic medication or benzodiazepine use could increase dementia risk. We tested this hypothesis using data from a UK cohort study.

Authors: Carlota M. Grossi, Kathryn Richardson, Chris Fox, Ian Maidment, Nicholas Steel, Yoon K. Loke, Antony Arthur, Phyo Kyaw Myint, Noll Campbell, Malaz Boustani, Louise Robinson, Carol Brayne, Fiona E. Matthews and George M. Savva

A four-stage process for intervention description and guide development of a practice-based intervention: refining the Namaste Care intervention implementation specification for people with advanced dementia prior to a feasibility cluster randomised trial

Some interventions are developed from practice, and implemented before evidence of effect is determined, or the intervention is fully specified. An example is Namaste Care, a multi-component intervention for p...

Authors: Catherine Walshe, Julie Kinley, Shakil Patel, Claire Goodman, Frances Bunn, Jennifer Lynch, David Scott, Anne Davidson Lund, Min Stacpoole, Nancy Preston and Katherine Froggatt

Musculoskeletal pain and new-onset poor physical function in elderly survivors of a natural disaster: a longitudinal study after the great East Japan earthquake

Functional disability is a significant problem after natural disasters. Musculoskeletal pain is reported to increase after disasters, which can cause functional disability among survivors. However, the effects...

Authors: Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Ichiro Tsuji and Eiji Itoi

A randomized controlled efficacy study of the Medido medication dispenser in Parkinson’s disease

Complex medication schedules in Parkinson’s disease (PD) result in lower therapy adherence, which contributes to suboptimal therapy and clinical deterioration. Medication reminder systems might improve therapy...

Authors: K. Hannink, L. ter Brake, N.G.M. Oonk, A.A. Wertenbroek, M. Piek, L. Vree-Egberts, M.J. Faber, J. van der Palen and L.D. Dorresteijn

Melatonin for the prevention of postoperative delirium in older adults: a systematic review and meta-analysis

Older surgical patients are at high risk of developing postoperative delirium. Non-pharmacological strategies are recommended for delirium prevention, but no pharmacological agents have compelling evidence to ...

Authors: Ashley M. Campbell, David Rhys Axon, Jennifer R. Martin, Marion K. Slack, Lea Mollon and Jeannie K. Lee

Reference values and associated factors of hand grip strength in elderly Saudi population: a cross-sectional study

Hand grip strength (HGS) is an important function of upper extremities for older adults. Several studies have shown the importance of measuring HGS in different settings. Current established normative values o...

Authors: Bader Alqahtani, Aqeel Alenazi, Mohammed Alshehri, Mohammed Alqahtani and Ragab Elnaggar

Dose-response association between physical activity and sedentary time categories on ageing biomarkers

Physical activity and sedentary behaviour have been suggested to independently affect a number of health outcomes. To what extent different combinations of physical activity and sedentary behaviour may influen...

Authors: Asier Mañas, Borja del Pozo-Cruz, Irene Rodríguez-Gómez, Javier Leal-Martín, José Losa-Reyna, Leocadio Rodríguez-Mañas, Francisco J. García-García and Ignacio Ara

Functional impairment and serum albumin predict in-hospital mortality in nonagenarians with acute infection: a retrospective cohort study

Acute infection leads to substantial mortality in the nonagenarian population. However, the predictive efficacies of functional status and biochemical indexes for in-hospital mortality in these patients remain...

Authors: Wei Huang, Ying Sun, Yunli Xing and Cuiying Wang

The impact of an orthogeriatric intervention in patients with fragility fractures: a cohort study

While orthogeriatric care to patients with hip fractures is established, the impact of similar intervention in patients with fragility fractures in general is lacking. Therefore, we aimed to assess the impact ...

Authors: Charlotte Abrahamsen, Birgitte Nørgaard, Eva Draborg and Morten Frost Nielsen

Social position and geriatric syndromes among Swedish older people: a population-based study

Older people with a low social position are at higher risk of poor health outcomes compared to those with a higher social position. Whether lower social position also increases the risk of geriatric syndromes ...

Authors: C. Rausch, Y. Liang, U. Bültmann, S. E. de Rooij, K. Johnell, L. Laflamme and J. Möller

Care trajectories of chronically ill older adult patients discharged from hospital: a quantitative cross-sectional study using health insurance claims data

For older adults, a good transition from hospital to the primary or long-term care setting can decrease readmissions. This paper presents the 6-month post-discharge healthcare utilization of older adults and d...

Authors: Yvonne de Man, Femke Atsma, Wilma Jonkers, Sophia E. J. A. de Rooij, Gert P. Westert, Patrick P. T. Jeurissen and A. Stef Groenewoud

Prevalence of mild hyponatremia and its association with falls in older adults admitted to an emergency geriatric medicine unit (the MUPA unit)

Hyponatremia is the most common electrolyte disorder in older adults and it can increase morbidity and mortality. Approximately one in three older adults fall each year; mild chronic hyponatremia can predispos...

Authors: Sophie Boyer, Caroline Gayot, Charlotte Bimou, Thomas Mergans, Patrick Kajeu, Muriel Castelli, Thierry Dantoine and Achille Tchalla

Development and validation of an algorithm to assess risk of first-time falling among home care clients

The falls literature focuses on individuals with previous falls, so little is known about individuals who have not experienced a fall in the past. Predicting falls in those without a prior event is critical fo...

Authors: Ayse Kuspinar, John P. Hirdes, Katherine Berg, Caitlin McArthur and John N. Morris

A systematic literature review of the assessment of treatment burden experienced by patients and their caregivers

Many older adults with multiple chronic conditions, particularly those who are functionally impaired, spend considerable time juggling the competing demands of managing their conditions often assisted by careg...

Authors: Orla C. Sheehan, Bruce Leff, Christine S. Ritchie, Sarah K. Garrigues, Lingsheng Li, Debra Saliba, Roya Fathi and Cynthia M. Boyd

Effects of depression, dementia and delirium on activities of daily living in elderly patients after discharge

The three geriatric conditions, depression, dementia and delirium (3D’s), are common among hospitalized older patients and often lead to impairments of activities of daily living. The aim of this study is to e...

Authors: Ching-Fu Weng, Kun-Pei Lin, Feng-Ping Lu, Jen-Hau Chen, Chiung-Jung Wen, Jui-Hua Peng, Ailun Heather Tseng and Ding-Cheng Chan

Prevalence of Potentially Inappropriate Medication use in older drivers

Potentially Inappropriate Medication (PIM) use has been studied in a variety of older adult populations across the world. We sought to examine the prevalence and correlates of PIM use in older drivers.

Authors: Guohua Li, Howard F. Andrews, Stanford Chihuri, Barbara H. Lang, Cheng Shiun Leu, David P. Merle, Abigail Gordon, Thelma J. Mielenz, David Strogatz, David W. Eby, Marian E. Betz, Carolyn DiGuiseppi, Vanya C. Jones, Lisa J. Molnar and Linda L. Hill

Theory and Design of the Community for successful ageing (ComSA) program in Singapore: connecting BioPsychoSocial health and quality of life experiences of older adults

Despite the emphasis on holistic health promotion in community programs for older people, few studies explicitly consider how BioPsychoSocial (BPS) health elements are interconnected and function to improve Qu...

Authors: Su Aw, Gerald C. H. Koh, Chuen Seng Tan, Mee Lian Wong, Hubertus J. M. Vrijhoef, Susana Concordo Harding, Mary Ann B. Geronimo and Zoe J. L. Hildon

Braden scale for assessing pneumonia after acute ischaemic stroke

The prevention of pneumonia is critical for patients with acute ischaemic stroke (AIS). The six subscales in the Braden Scale seem to be related to the occurrence of pneumonia. We aimed to evaluate the feasibi...

Authors: Yunlong Ding, Yazhou Yan, Jiali Niu, Yanrong Zhang, Zhiqun Gu, Ping Tang and Yan Liu

Needs and skills of informal caregivers to care for a dependent person: a cross-sectional study

The world is facing many socio-demographic changes, such as an increased average life expectancy and the presence of chronic and non-communicable diseases, which in turn, leads to an enhanced dependency on oth...

Authors: Maria dos Anjos Coelho Rodrigues Dixe, Liliana Fernanda da Conceição Teixeira, Timóteo João Teixeira Camacho Coelho Areosa, Roberta Caçador Frontini, Teresa de Jesus Almeida Peralta and Ana Isabel Fernandes Querido