Table 1 Demographics and neuropsychological assessments (mean ± SD)

Demographic data

Gender (male)^b

8 (40%)

12 (60%)

0.206

Age (years)

63.85 ± 7.74

67.05 ± 4.67

0.127

Education (years)

11.20 ± 3.04

10.80 ± 3.72

0.678

BMI

25.55 ± 3.41

23.73 ± 2.41

0.091

Diabetes mellitus^b

6 (30%)

3 (15%)

0.256

Constipation^b

1 (5%)

0 (0%)

0.311

Smoking^b

1 (5%)

0 (0%)

0.311

APOE ε4^b

6 (30%)

Amyloid Centiloid score

35.20 ± 40.93

Medication

 Donepezil^b

0

12 (60%)

 Rivastigmine^b

0

2 (10%)

Neuropsychological data

MMSE

29.40 ± 0.82

27.00 ± 1.81

< 0.001^*

CASI

96.75 ± 2.66

88.37 ± 7.03

< 0.001^*

CVVLT

 Total

29.65 ± 3.51

24.15 ± 4.91

< 0.001^*

 Delayed

8.80 ± 0.52

5.55 ± 2.67

< 0.001^*

GDS

1.10 ± 3.08

2.85 ± 1.87

< 0.001^*

NPI

 Total score

2.80 ± 2.65

 Behavioral composite score

0.20 ± 0.41

 Affective composite score

2.55 ± 2.68

 Psychotic composite score

0.05 ± 0.22

DST

 Forward

7.70 ± 1.84

 Backward

4.50 ± 1.36

VFT-animal

12.50 ± 4.40

TMT-B (s)

71.85 ± 32.20

FAQ

4.55 ± 5.07

LQ

5.40 ± 0.99