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Table 2 PREVENT imaging comprehensive dementia protocol < 20 min of scan time

From: A longitudinal magnetic resonance imaging study of neurodegenerative and small vessel disease, and clinical cognitive trajectories in non demented patients with transient ischemic attack: the PREVENT study

Imaging Sequence Mechanistic Target Endpoint Geometric Parameters (2D/3D, FOV) Acquisition Parameters (TE/TR/flip)
3-plane localizer    2D, 24 cm, 8 mm/ 8 mm, 33, 256 × 128 1.3 ms/ 4.8 ms/ 30°
High Resolution T1-weighted Atrophy Primary and secondary outcome 3D, 24 cm2 2.0 mm/ 0 mm, 70, 256 × 256 3 ms/ 7 ms/ 8° (minTE, minTR)
3D T2-weighted FLAIR WML volume Predictor of primary outcome 3D, 24 cm, 1 mm/ 0 mm, 38, 256 × 256 140 ms/ 9000 ms/ 90°
Axial 3D QSM Neurodegeneration Brain iron content Predictor of primary outcome 3D, 24 cm, 2 mm/0 mm, 192 × 192 29.5 ms/3 ms/8°
3D Proton Density WML volume   3D SPGR, 1 mm/ 0 mm, 256 × 256  
Diffusion tensor DWI Microstructure Acute cytotoxic ischemia   2D, 24 cm, 3.5 mm/ 0 mm, 38, 144 × 144 matrix 70 ms - 80 ms/ 13,000 ms/ 90°
Axial T2 star Microhemorrhage   2D, 24 cm, 3.5 mm/ 0 mm, 38, 256 × 224 140 ms/ 9000 ms/ 90°7