Beard JR, Officer A, de Carvalho IA, Sadana R, Pot AM, Michel J, Lloyd-Sherlock P, Epping-Jordan JE, Peeters GG, Mahanani WR. The world report on ageing and health: a policy framework for healthy ageing. Lancet. 2015;387:2145–54.
Article
PubMed
PubMed Central
Google Scholar
Chatterji S, Byles J, Cutler D, Seeman T, Verdes E. Health, functioning, and disability in older adults—present status and future implications. Lancet. 2015;385:563–75.
Article
PubMed
Google Scholar
Fielding RA, Vellas B, Evans WJ, Bhasin S, Morley JE, Newman AB, Abellan van Kan G, Andrieu S, Bauer J, Breuille D. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. JAMA. 2011;12(4):249–56.
Google Scholar
Cruz-Jentoft AJ, Landi F, Schneider SM, Zúñiga C, Arai H, Boirie Y, Chen L-K, Fielding RA, Martin FC, Michel J-P. Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the international sarcopenia initiative (EWGSOP and IWGS). Age Ageing. 2014;43(6):748–59.
Article
PubMed
PubMed Central
Google Scholar
Janssen I, Heymsfield SB, Wang Z, Ross R. Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr. J Applied Physiol. 2000;89(1):81–8.
Article
CAS
Google Scholar
Zamboni M, Mazzali G, Fantin F, Rossi A, Di Francesco V. Sarcopenic obesity: a new category of obesity in the elderly. Nutr Metab Cardiovasc Dis. 2008;18(5):388–95.
Article
CAS
PubMed
Google Scholar
Hubbard RE, Lang IA, Llewellyn DJ, Rockwood K. Frailty, body mass index, and abdominal obesity in older people. J Gerontol A Biol Sci Med Sci. 2010;65(4):377–81.
Article
PubMed
Google Scholar
Houston DK, Nicklas BJ, Zizza CA. Weighty concerns: the growing prevalence of obesity among older adults. JADA. 2009;109(11):1886–95.
Article
CAS
Google Scholar
Alley DE, Ferrucci L, Barbagallo M, Studenski SA, Harris TB. A research agenda: the changing relationship between body weight and health in aging. J Gerontol A Biol Sci Med Sci. 2008;63(11):1257–9.
Article
PubMed
PubMed Central
Google Scholar
Villareal DT, Apovian CM, Kushner RF, Klein S. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Obes Res. 2005;13(11):1849–63.
Article
PubMed
Google Scholar
Weinheimer EM, Sands LP, Campbell WW. A systematic review of the separate and combined effects of energy restriction and exercise on fat-free mass in middle-aged and older adults: implications for sarcopenic obesity. Nutr Rev. 2010;68(7):375–88.
Article
PubMed
Google Scholar
Ballor DL, Katch V, Becque M, Marks C. Resistance weight training during caloric restriction enhances lean body weight maintenance. Am J Clin Nutr. 1988;47(1):19–25.
CAS
PubMed
Google Scholar
Miller S, Wolfe RR. The danger of weight loss in the elderly. J Nutr Health Aging. 2008;12(7):487–91.
Article
CAS
PubMed
Google Scholar
Villareal DT, Chode S, Parimi N, Sinacore DR, Hilton T, Armamento-Villareal R, Napoli N, Qualls C, Shah K. Weight loss, exercise, or both and physical function in obese older adults. New Eng J Med. 2011;364(13):1218–29.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chomentowski P, Dubé JJ, Amati F, Stefanovic-Racic M, Zhu S, Toledo FG, Goodpaster BH. Moderate exercise attenuates the loss of skeletal muscle mass that occurs with intentional caloric restriction–induced weight loss in older, overweight to obese adults. J Gerontol A Biol Sci Med Sci. 2009;64(5):575–80.
Article
PubMed
Google Scholar
Manini TM, Milsom VA, Dubyak P, Cesari M, Cheng J, Daniels MJ, Marsiske M, Pahor M, Leeuwenburgh C, Perri MG. Effects of a weight loss plus exercise program on physical function in overweight, older women: a randomized controlled trial. Clin Interv Aging. 2011;6:141–9.
PubMed
PubMed Central
Google Scholar
Porter Starr KN, Pieper CF, Orenduff MC, McDonald SR, McClure LB, Zhou R, Payne ME, Bales CW. Improved function with enhanced protein intake per meal: a pilot study of weight reduction in frail, obese older adults. J Gerontol A Biol Sci Med Sci. 2016;71(10):1369–75.
Article
PubMed
PubMed Central
Google Scholar
McDonald SR, Starr KNP, Mauceri L, Orenduff M, Granville E, Ocampo C, Payne ME, Pieper CF, Bales CW. Meal-based enhancement of protein quality and quantity during weight loss in obese older adults with mobility limitations: rationale and design for the MEASUR-UP trial. Contemporary Clinical Trials. 2015;40:112–23.
Article
PubMed
Google Scholar
Starr KNP, Orenduff MC, McDonald SR, Pieper CF, Mulder HC, Maloney K, Bales CW. Influence of daily and per meal protein intakes on function and body composition in frail, obese older adults undergoing weight reduction. FASEB J. 2016;30(1):411–9.
Google Scholar
Weijs PJ, Wolfe RR. Exploration of the protein requirement during weight loss in obese older adults. Clin Nutr. 2016;35(2):394–8.
Article
CAS
PubMed
Google Scholar
Backx E, Tieland M, Borgonjen-van den Berg K, Claessen P, van Loon L, de Groot L. Protein intake and lean body mass preservation during energy intake restriction in overweight older adults. IJO. 2016;40(2):299–304.
CAS
Google Scholar
Verreijen AM, Verlaan S, Engberink MF, Swinkels S, de Vogel-van den Bosch J, Weijs PJ. A high whey protein–, leucine-, and vitamin D–enriched supplement preserves muscle mass during intentional weight loss in obese older adults: a double-blind randomized controlled trial. Am J Clin Nutr. 2015;101(2):279–86.
Article
CAS
PubMed
Google Scholar
Beavers KM, Gordon M, Easter L, Beavers D, Hairston K, Nicklas B, Vitolins M. Effect of protein source during weight loss on body composition, cardiometabolic risk and physical performance in abdominally obese, older adults: a pilot feeding study. J Nutr Health Aging. 2015;19(1):87–95.
Article
CAS
PubMed
PubMed Central
Google Scholar
Coker RH, Miller S, Schutzler S, Deutz N, Wolfe RR. Whey protein and essential amino acids promote the reduction of adipose tissue and increased muscle protein synthesis during caloric restriction-induced weight loss in elderly, obese individuals. Nutr J. 2012; https://doi.org/10.1186/1475-2891-11-105.
Mojtahedi MC, Thorpe MP, Karampinos DC, Johnson CL, Layman DK, Georgiadis JG, Evans EM. The effects of a higher protein intake during energy restriction on changes in body composition and physical function in older women. J Gerontol A Biol Sci Med Sci. 2011;66(11):1218–25.
Article
PubMed
Google Scholar
Amamou T, Normandin E, Pouliot J, Dionne IJ, Brochu M, Riesco E. Effect of a high-protein energy-restricted diet combined with resistance training on metabolic profile in older individuals with metabolic impairments. J Nutr Health Aging. 2017;21(1):67–74.
Article
CAS
PubMed
Google Scholar
Breen L, Phillips SM. Skeletal muscle protein metabolism in the elderly: interventions to counteract the'anabolic resistance’ of ageing. Nutr Metab. 2011; https://doi.org/10.1186/1743-7075-8-68.
Bohé J, Low A, Wolfe RR, Rennie MJ. Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study. J Physiol. 2003;552(1):315–24.
Article
PubMed
PubMed Central
Google Scholar
Welle S, Thornton C, Jozefowicz R, Statt M. Myofibrillar protein synthesis in young and old men. Am J Physiol Endocrinol Metab. 1993;264(5):693–8.
Article
Google Scholar
Proctor D, Balagopal P, Nair KS. Age-related sarcopenia in humans is associated with reduced synthetic rates of specific muscle proteins. J Nutr. 1998;128(2):351–5.
Google Scholar
Cuthbertson D, Smith K, Babraj J, Leese G, Waddell T, Atherton P, Wackerhage H, Taylor PM, Rennie MJ. Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle. FASEB J. 2005;19(3):422–4.
CAS
PubMed
Google Scholar
Bauer J, Biolo G, Cederholm T, Cesari M, Cruz-Jentoft AJ, Morley JE, Phillips S, Sieber C, Stehle P, Teta D. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE study group. JAMA. 2013;14(8):542–59.
Google Scholar
Deutz NE, Bauer JM, Barazzoni R, Biolo G, Boirie Y, Bosy-Westphal A, Cederholm T, Cruz-Jentoft A, Krznariç Z, Nair KS. Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN expert group. Clin Nutr. 2014;33(6):929–36.
Article
CAS
PubMed
PubMed Central
Google Scholar
Semba RD, Lauretani F, Ferrucci L. Carotenoids as protection against sarcopenia in older adults. Arch Biochem Biophys. 2007;458(2):141–5.
Article
CAS
PubMed
Google Scholar
Lauretani F, Semba RD, Bandinelli S, Dayhoff-Brannigan M, Giacomini V, Corsi AM, Guralnik JM, Ferrucci L. Low plasma carotenoids and skeletal muscle strength decline over 6 years. J Gerontol A Biol Sci Med Sci. 2008;63(4):376–83.
Article
PubMed
PubMed Central
Google Scholar
Alipanah N, Varadhan R, Sun K, Ferrucci L, Fried L, Semba RD. Low serum carotenoids are associated with a decline in walking speed in older women. J Nutr Health Aging. 2009;13(3):170–5.
Article
CAS
PubMed
PubMed Central
Google Scholar
Urpi-Sarda M, Andres-Lacueva C, Rabassa M, Ruggiero C, Zamora-Ros R, Bandinelli S, Ferrucci L, Cherubini A. The relationship between urinary total polyphenols and the frailty phenotype in a community-dwelling older population: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2015;70(9):1141–7.
Article
PubMed
PubMed Central
Google Scholar
Rabassa M, Zamora-Ros R, Andres-Lacueva C, Urpi-Sarda M, Bandinelli S, Ferrucci L, Cherubini A. Association between both total baseline urinary and dietary polyphenols and substantial physical performance decline risk in older adults: a 9-year follow-up of the InCHIANTI study. J Nutr Health Aging. 2016;20(5):478–84.
Article
CAS
PubMed
PubMed Central
Google Scholar
Robinson SM, Jameson KA, Batelaan SF, Martin HJ, Syddall HE, Dennison EM, Cooper C, Sayer AA. Diet and its relationship with grip strength in community-dwelling older men and women: the Hertfordshire cohort study. J Am Geriatr Soc. 2008;56(1):84–90.
Article
PubMed
Google Scholar
Martin H, Sayer AA, Jameson K, Syddall H, Dennison EM, Cooper C, Robinson S. Does diet influence physical performance in community-dwelling older people? Findings from the Hertfordshire cohort study. Age Ageing. 2011;40(2):181–6.
Article
PubMed
Google Scholar
Kim J, Lee Y, Kye S, Chung YS, Kim KM. Association between healthy diet and exercise and greater muscle mass in older adults. J Am Geriatr Soc. 2015;63(5):886–92.
Article
PubMed
Google Scholar
Kim J, Lee Y, Kye S, Chung Y-S, Kim K-M. Association of vegetables and fruits consumption with sarcopenia in older adults: the fourth Korea National Health and nutrition examination survey. Age Ageing. 2015;44(1):96–102.
Article
PubMed
Google Scholar
Hashemi R, Motlagh AD, Heshmat R, Esmaillzadeh A, Payab M, Yousefinia M, Siassi F, Pasalar P, Baygi F. Diet and its relationship to sarcopenia in community dwelling Iranian elderly: a cross sectional study. Nutrition. 2015;31(1):97–104.
Article
PubMed
Google Scholar
Talegawkar SA, Bandinelli S, Bandeen-Roche K, Chen P, Milaneschi Y, Tanaka T, Semba RD, Guralnik JM, Ferrucci L. A higher adherence to a Mediterranean-style diet is inversely associated with the development of frailty in community-dwelling elderly men and women. J Nutr. 2012;142(12):2161–6.
Article
CAS
PubMed
PubMed Central
Google Scholar
León-Muñoz LM, García-Esquinas E, López-García E, Banegas JR, Rodríguez-Artalejo F. Major dietary patterns and risk of frailty in older adults: a prospective cohort study. BMC Med. 2015; https://doi.org/10.1186/s12916-014-0255-6.
Fougère B, Mazzuco S, Spagnolo P, Guyonnet S, Vellas B, Cesari M, Gallucci M. Association between the Mediterranean-style dietary pattern score and physical performance: results from TRELONG study. J Nutr Health Aging. 2016;20(4):415–9.
Article
PubMed
Google Scholar
Milaneschi Y, Bandinelli S, Corsi AM, Lauretani F, Paolisso G, Dominguez LJ, Semba RD, Tanaka T, Abbatecola AM, Talegawkar SA. Mediterranean diet and mobility decline in older persons. Exp Gerontol. 2011;46(4):303–8.
Article
PubMed
Google Scholar
Shahar DR, Houston DK, Hue TF, Lee JS, Sahyoun NR, Tylavsky FA, Geva D, Vardi H, Harris TB. Adherence to Mediterranean diet and decline in walking speed over 8 years in community-dwelling older adults. J Am Geriatr Soc. 2012;60(10):1881–8.
Article
PubMed
PubMed Central
Google Scholar
Tyrovolas S, Haro J-M, Mariolis A, Piscopo S, Valacchi G, Bountziouka V, Anastasiou F, Zeimbekis A, Tyrovola D, Foscolou A. Skeletal muscle mass and body fat in relation to successful ageing of older adults: the multi-national MEDIS study. Arch Gerontol Geriat. 2016;66:95–101.
Article
Google Scholar
Kelaiditi E, Jennings A, Steves C, Skinner J, Cassidy A, MacGregor A, Welch A. Measurements of skeletal muscle mass and power are positively related to a Mediterranean dietary pattern in women. Osteoporos Int. 2016;27(11):3251–60.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zbeida M, Goldsmith R, Shimony T, Vardi H, Naggan L, Shahar DR. Mediterranean diet and functional indicators among older adults in non-Mediterranean and Mediterranean countries. J Nutr Health Aging. 2014;18(4):411–8.
Article
CAS
PubMed
Google Scholar
Crichton G, Elias M, Alkerwi A, Buckley J. Intake of Lutein-rich vegetables is associated with higher levels of physical activity. Nutrients. 2015;7(9):8058–71.
Article
CAS
PubMed
PubMed Central
Google Scholar
Thomson RL, Coates AM, Howe PR, Bryan J, Matsumoto M, Buckley JD. Increases in plasma lutein through supplementation are correlated with increases in physical activity and reductions in sedentary time in older adults. Nutrients. 2014;6(3):974–84.
Article
CAS
PubMed
PubMed Central
Google Scholar
Winter JE, MacInnis RJ, Wattanapenpaiboon N, Nowson CA. BMI and all-cause mortality in older adults: a meta-analysis. Am J Clin Nutr. 2014; https://doi.org/10.3945/ajcn.113.068122.
Kim J, Wang Z, Heymsfield SB, Baumgartner RN, Gallagher D. Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry method. Am J Clin Nutr. 2002;76(2):378–83.
CAS
PubMed
Google Scholar
Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, Garry PJ, Lindeman RD. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol. 1998;147(8):755–63.
Article
CAS
PubMed
Google Scholar
Nana A, Slater GJ, Hopkins WG, Burke LM. Effects of daily activities on dual-energy X-ray absorptiometry measurements of body composition in active people. Med Sci Sports Exerc. 2012;44(1):180–9.
Article
PubMed
Google Scholar
Kerr A, Slater GJ, Byrne N, Nana A. Reliability of 2 different positioning protocols for dual-energy X-ray absorptiometry measurement of body composition in healthy adults. J Clin Densitom. 2015;19(3):282–9.
Article
PubMed
Google Scholar
Schaubert K, Bohannon R. Reliability and validity of three strength measures obtained from community-dwelling elderly persons. J Strength Cond Res. 2005;19(3):717–20.
PubMed
Google Scholar
Norman K, Stobäus N, Gonzalez MC, Schulzke J-D, Pirlich M. Hand grip strength: outcome predictor and marker of nutritional status. Clin Nutr. 2011;30(2):135–42.
Article
PubMed
Google Scholar
Guralnik J, Simonsick E, Ferrucci L, Glynn R, Berkman L, Blazer D, Scherr P, Wallace R. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol. 1994;49:85–94.
Article
Google Scholar
Guralnik JM, Ferrucci L, Pieper CF, Leveille SG, Markides KS, Ostir GV, Studenski S, Berkman LF, Wallace RB. Lower extremity function and subsequent disability consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci. 2000;55(4):221–31.
Article
Google Scholar
Guralnik JM, Ferrucci L, Simonsick EM, Salive ME, Wallace RB. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability. New Eng J Med. 1995;332(9):556–62.
Article
CAS
PubMed
Google Scholar
Hurtig-Wennlöf A, Hagströmer M, Olsson LA. The international physical activity questionnaire modified for the elderly: aspects of validity and feasibility. Public Health Nutr. 2010;13(11):1847–54.
Article
PubMed
Google Scholar
Jancey J, Lee A, Howat P, Clarke A, Wang K, Shilton T. Reducing attrition in physical activity programs for older adults. J Ageing Phys Activity. 2007;15(2):152–65.
Article
Google Scholar
Booth ML, Ainsworth BE, Pratt M, Ekelund U, Yngve A, Sallis JF, Oja P. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003;195:3508–1381.
Google Scholar
Ware JE. SF-36 health survey update. Spine. 2000;25(24):3130–9.
Article
PubMed
Google Scholar
Sanson-Fisher RW, Perkins JJ. Adaptation and validation of the SF-36 health survey for use in Australia. J Clin Epidemiol. 1998;51(11):961–7.
Article
CAS
PubMed
Google Scholar
Fernández-Ballart JD, Piñol JL, Zazpe I, Corella D, Carrasco P, Toledo E, Perez-Bauer M, Martínez-González MÁ, Salas-Salvadó J, Martín-Moreno JM. Relative validity of a semi-quantitative food-frequency questionnaire in an elderly Mediterranean population of Spain. BJN. 2010;103(12):1808–16.
Article
Google Scholar
Martínez-González MA, García-Arellano A, Toledo E, Salas-Salvado J, Buil-Cosiales P, Corella D, Covas MI, Schröder H, Arós F, Gómez-Gracia E. A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: the PREDIMED trial. PLoS One. 2012; https://doi.org/10.1371/journal.pone.0043134.
Mifflin MD, St Jeor ST, Hill LA, Scott BJ, Daugherty SA, Koh Y. A new predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr. 1990;51(2):241–7.
CAS
PubMed
Google Scholar
Kim JE, O’Connor LE, Sands LP, Slebodnik MB, Campbell WW. Effects of dietary protein intake on body composition changes after weight loss in older adults: a systematic review and meta-analysis. Nutr Rev. 2016;74(3):210–24.
Article
PubMed
PubMed Central
Google Scholar
Hunter GR, McCarthy JP, Bamman MM. Effects of resistance training on older adults. Sports Med. 2004;34(5):329–48.
Article
PubMed
Google Scholar
Muscaritoli M, Anker SD, Argilés J, Aversa Z, Bauer JM, Biolo G, Boirie Y, Bosaeus I, Cederholm T, Costelli P, et al. Consensus definition of sarcopenia, cachexia and pre-cachexia: joint document elaborated by Special Interest Groups (SIG) “cachexia-anorexia in chronic wasting diseases” and “nutrition in geriatrics”. Clin Nutr. 2010;29(2):154–9.
Article
CAS
PubMed
Google Scholar
Malafarina V, Úriz-Otano F, Iniesta R, Gil-Guerrero L. Sarcopenia in the elderly: diagnosis, physiopathology and treatment. Maturitas. 2012;71(2):109–14.
Article
PubMed
Google Scholar
Fiedor J, Burda K. Potential role of carotenoids as antioxidants in human health and disease. Nutrients. 2014;6(2):466–88.
Article
PubMed
PubMed Central
Google Scholar
Woodside JV, McGrath AJ, Lyner N, McKinley MC. Carotenoids and health in older people. Maturitas. 2015;80(1):63–8.
Article
CAS
PubMed
Google Scholar
Khurana S, Venkataraman K, Hollingsworth A, Piche M, Tai T. Polyphenols: benefits to the cardiovascular system in health and in aging. Nutrients. 2013;5(10):3779–827.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bulotta S, Celano M, Lepore SM, Montalcini T, Pujia A, Russo D. Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases. J Transl Med. 2014. doi:https://doi.org/10.1186/s12967-014-0219-9.
Liu RH. Health-promoting components of fruits and vegetables in the diet. Advances in nutrition: an international review. Journal. 2013;4(3):384–92.
Google Scholar