Is age a limit for surgical treatment of gastric cancer?
© Uzzau et al; licensee BioMed Central Ltd. 2009
Published: 1 April 2009
Aim of the study
The incidence of the gastric cancer is 23% of all the tumours in Europe, and increases with progressing by age with a prevalence of 140 by 100,000/year for the subjects with more than 75 years. To the light of this consideration we analysed retrospectively the results obtained with the surgical therapy of the gastric cancer in the elderly patient.
Materials and methods
From 1989 to 2007, 291 consecutive patients underwent surgical resection with curative (R0) intent. We have collected and analysed data concerning the characteristics of the patients, type of surgical treatment and the tumour itself. Data processing was performed using SPSS 13.0 for Windows Evaluation Version (SPSS Inc., Chicago, IL, USA).
The rate of tumor relapse has been of 41.2% in young people and 28.9% (p = 0.033) in the elders. At the multivariate analysis stage of the disease and the ASA score resulted negative prognostic factors for young patients, while LR, ASA score and anastomotic leak in the elders group.
Age is not a factor limiting surgical therapy for patients affected by gastric cancer. Patients over 70 benefit from gastrectomy and/or gastric resection in terms of disease-free survival with an outcome comparable to the young patients. Particular attention must be placed to rule out and correct invalidating systemic pathologies.
This article is published under license to BioMed Central Ltd.