The surgical treatment of colorectal liver metastasis in the elderly
© Donati et al; licensee BioMed Central Ltd. 2009
Published: 1 April 2009
The recent advances in the surgical treatment (more precise diagnostic features, new surgical devices, advancement in intensive care) allowed in the last 15 years an extension of surgical indication to a liver resection to a larger population of patients also in the elderly. Aim of this work is to evaluate the indication and limits of the surgical treatment of colorectal liver metastases in the elderly.
Patients and methods
In Group A, 10 patients showed a minor complication (grade I–II) (17.5%) and 12 patients a major one (grade III–V) (21%) while in Group B were respectively 10 (19.6%) and 9(17.6%). In Group A the average postoperative recovery time was 13.5 days (range 6–38), while in Group B it was 12.08 days (range 5–27). In Group A three patients (5.2%) died for major complications, while in Group B we observed 1 perioperative death (~2%). The survival-rate was similar in both groups; one and three years overall survival-rate was respectively Group A 68% and 42% vs Group B 65% and 40%.
About a half of hepatic resections of colorectal liver metastasis are performed in old patient (over 65 years). Our results suggest that the limits for hepatic resection in the elderly are the same as for younger patients. In the over 65 years group there is the tendency to perform less major liver resections in order to achieve the R0-status. The morbidity seems to be comparable in both groups also if the perioperative mortality is more than doubled in over 65 years patients. The long-term survival-rate is not to correlate to the age of the patients, and also major hepatic resection are relative safe and justified in the elderly in order to achieve oncological results.
This article is published under license to BioMed Central Ltd.