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Which older people decline participation in a primary care trial of physical activity and why: insights from a mixed methods approach



Physical activity is of vital importance to older peoples’ health. Physical activity intervention studies with older people often have low recruitment, yet little is known about non-participants.


Patients aged 60–74 years from three UK general practices were invited to participate in a nurse-supported pedometer-based walking intervention. Demographic characteristics of 298 participants and 690 non-participants were compared. Health status and physical activity of 298 participants and 183 non-participants who completed a survey were compared using age, sex adjusted odds ratios (OR) (95% confidence intervals). 15 non-participants were interviewed to explore perceived barriers to participation.


Recruitment was 30% (298/988). Participants were more likely than non-participants to be female (54% v 47%; p = 0.04) and to live in affluent postcodes (73% v 62% in top quintile; p < 0.001). Participants were more likely than non-participants who completed the survey to have an occupational pension OR 2.06 (1.35-3.13), a limiting longstanding illness OR 1.72 (1.05-2.79) and less likely to report being active OR 0.55 (0.33-0.93) or walking fast OR 0.56 (0.37-0.84). Interviewees supported general practice-based physical activity studies, particularly walking, but barriers to participation included: already sufficiently active, reluctance to walk alone or at night, physical symptoms, depression, time constraints, trial equipment and duration.


Gender and deprivation differences suggest some selection bias. However, trial participants reported more health problems and lower activity than non-participants who completed the survey, suggesting appropriate trial selection in a general practice population. Non-participant interviewees indicated that shorter interventions, addressing physical symptoms and promoting confidence in pursuing physical activity, might increase trial recruitment and uptake of practice-based physical activity endeavours.

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Physical activity (PA) reduces the risk of over 20 adverse health conditions in older people, as well as improving emotional wellbeing [1]. Physical inactivity is the fourth leading cause of death worldwide [2] and a major cost burden on health services [1].

Primary care has a key role in encouraging older people to become more active [3] and primary care nurses often deliver new National Health Service (NHS) Health Checks, assessing PA levels using the General Practice Physical Activity Questionnaire (GPPAQ) [4] and advising on increasing PA in adults up to age 74 [5].

Primary care PA studies report low response rates (46% for questionnaires [6]; 6-35% for intervention studies [7, 8]). Low recruitment can lead to selection biases, thereby threatening generalisation of results. However, evidence on selection bias is contradictory: some studies reporting that trial participants are more active [9, 10], and have better health [11] and functional status than non-participants [7], with other studies reporting that they have poorer health [9, 12]. Such contradictions hinder the translation of findings and highlight the importance of studying trial non-participants, including a qualitative component to understand better their decision.

The PACE-Lift trial is a three month intervention designed to increase walking, using pedometers, accelerometers and one-to-one nurse consultations for older primary care patients. The target number of patients to be recruited was 300. The protocol fully describes the study design and trial interventions [13].


We aimed to elucidate factors influencing participation in a primary care PA trial in older adults by: 1) comparing demographic details of all those invited to participate; 2) comparing self-reported socio-demographic characteristics, health status and PA levels of participants with those of non-participants who completed a survey; and 3) exploring in interviews a sample of non-participants’ perceived barriers to participation.



A two-phase mixed-methods sequential explanatory design was used. Phase one involved collection of quantitative data using general practice records and a questionnaire survey. Phase two involved semi-structured interviews with a sample of trial non-participants. The rationale for this approach was to explain quantitative results by exploring non-participants’ views in more breadth and depth [14].


Three general practices in Oxfordshire and Berkshire, United Kingdom. Practices were selected that had the following: a list size >10,000 patients or >1400 patients aged 60–74 years; a practice nurse interested in carrying out the physical activity interventions; and the availability of a room for the research assistant.


Patients aged 60–74 years registered at participating practices were invited to take part in the trial if they could walk outside and had no contraindications to increasing PA. Computerised primary care records were screened by Read codes for exclusions and random samples of households were selected. (If there were 2 members of a couple living at the same address who were both potentially eligible this was a ‘double’ household; if there was only one person potentially eligible this was a ‘single’ household). General practitioners (family physicians) then scrutinised these for further exclusions, before posting study invitations (Figure 1). The invitation included trial information and a response sheet with the options of i) trial participation, ii) completing a survey or iii) no further contact. There were 298 trial participants and 690 non participants, of whom 183 completed a questionnaire.

Figure 1
figure 1

PACE-Lift Trial Recruitment and Selection of Non-Participant Interviewee Sample.

Ethical approval

This was provided by NRES Committee Oxford C 11/H0606/2.


Quantitative (Phase 1)

Postcode information recorded in computerised primary care registers allowed us to assign an index of multiple deprivation (IMD) score based on material deprivation measures, to rank individuals using national quintiles [15].

Participants and 183 non-participants completed a ‘Health and Physical Activity Baseline Survey’, (Table 1). Self-reported PA was assessed by GPPAQ [4].

Table 1 Comparisons between participants and all non-participants

The odds ratios (ORs) for participating by various characteristics were estimated using logistic regression, adjusting as appropriate for possible confounding variables. Trends in ORs across IMD fifths were modelled by fitting IMD fifths as a continuous categorical variable coded 1–5. Trends across GPPAQ and General Health categories were similarly assessed, while a likelihood ratio test was used to test for variability in ORs between marital status categories.

Qualitative (Phase 2)

Permission to contact trial non-participants for a 10-minute interview was requested on the survey. Of the 183 non-participants surveyed, 77 who gave permission and 106 who did not were compared in terms of age, gender, whether invited as a couple or not, BMI and self-reported PA (GPPAQ). Fifteen of the 77 were telephoned and interviewed (Figure 1). Interviewees were purposively selected to provide: males and females of varying ages (60–74), invited to participate as an individual or a couple, samples from all three practices. Face-to-face or telephone interviews were offered and written or audio-recorded consent obtained. Recruitment stopped when no new themes were identified.

Development of interview schedule

The interviewer (AR) was a research assistant unknown to the interviewees. The semi-structured interview schedule was developed collaboratively and iteratively between AR, CV, AW and TH.

All interviews were initiated with an open question: What was your main reason for deciding not to take part in the PACE-Lift study? Probing then used previous questionnaire responses and additional questions. Possible reasons explored were: lack of time; unable/uninterested to increase PA; already physically active; not interested in research; do not want to be allocated by chance; length of programme; travel difficulties; individual versus group consultations; and trial equipment. Further trial issues were then explored: venue (e.g. general practice versus leisure centre); walking versus other PA interventions; group versus individual nurse contact; other factors that would have encouraged involvement.

Qualitative analysis

The interviews were transcribed verbatim. Transcripts were subjected to an initial analysis stage ‘data reduction’ [16] involving selecting and transforming the data as meanings and insights from the words of interviewees. AR uploaded the data onto QSR Nvivo (V9.0, Scientific Software) and read each transcript several times. This enabled identification of patterns both within and across transcripts with the aim of ensuring that recurrent codes were subject to closer scrutiny; alternative interpretations were explored, as advised in the qualitative analysis coding manual [16]. The initial thematic framework was discussed during monthly face-to-face meetings with co-researchers who had read and coded the 15 transcripts independently, discrepancies were resolved and additional codes refined until consensus was reached. Nvivo keyword searches were used to identify overlooked material.


Comparison of participants and all non-participants using data from computerised primary care records (Table 1)

Trial recruitment was 30% (298/988). Participants were slightly but not significantly younger than non-participants (Table 1.) They were more likely to be female (p = 0.04) but being invited as a couple did not affect response. More participants lived in the most affluent quintile of Index of Multiple Deprivation, 73%, compared with 62% of non-participants (p < 0.001). However, the overall sample from the three practices was relatively affluent, with 65% (643/988) living in the least deprived quintile of deprivation, compared to 20% nationally [15].

Comparison of participants and non-participants completing the survey (Table 2)

Table 2 Comparisons between participants and non-participants who responded to the survey

Trial participants and non-participants completing the survey did not differ in marital or retirement status or whether they had been invited to take part as a couple. Smoking status and ethnicity showed no differences, but as only 6% were smokers and only about 1% were non-white, these comparisons lacked statistical power. However, participants were more likely to have an occupational pension, adjusted OR 2.06 (1.35-3.13). Trial participation was positively associated with having a limiting long-standing illness, adjusted OR 1.72 (1.05-2.79) and having one or more chronic diseases, adjusted OR 1.68 (1.14-2.47). Participants tended to be overweight or obese adjusted OR 1.40 (0.93-2.09) and in pain adjusted OR 1.43 (0.96-2.12), but neither difference was statistically significant. General health, use of a walking aid, falls, number of medications, mobility or self-care problems, anxiety or depression, showed no association with participation. Participation was significantly associated with lower self-reported PA: slower walking pace, adjusted OR 0.56 (0.37-0.84) and lower activity levels, adjusted OR 0.55 (0.33-0.93). The main reasons given on the survey for non-participation were: already physically active (67%); time constraints (44%); lack of interest (25%).

Qualitative interview participant selection and findings (Table 3)

Table 3 Key themes from the transcripts identifying interviewees’ reasoning behind their decision not to participate in the trial

Amongst trial non-participants, the 77 who agreed to be approached for an interview were compared to those who did not (106). There were no statistically significant differences in age group 32% (24/77) versus 39% (41/106) age 70–75 (p = 0.37); gender 53% (41/77) versus 47% (50/106) male (p = 0.42); invited as a couple 51% (39/77) versus 52% (55/106) (p = 0.87); BMI 54% (37/69) versus 64% (59/92) overweight or obese (p = 0.18) or IMD score 71% (55/77) versus 73% (77/106) in least deprived quintile (p = 0.59). There was a significant difference in self-reported PA, with those who agreed to be interviewed more likely to answer the question and to self-report higher PA levels, 53% (40/76) versus 35% (31/89) categorised as “active” on GPPAQ (p = 0.021). Table 3 summarises key themes from the 15 interviews conducted. Barriers to trial participation included reluctance to walk either alone, in the evening, or in bad weather, linked to a fear of falling in wet weather and reduced confidence in pursuing PA. Poor physical and psychological health, symptoms of medical conditions, particularly arthritis and joint pain, psychological health concerns such as depression and low energy levels reduced the desire to exercise, as did a fear of “overdoing things”, with the view that PA might cause “more harm than good”. The predominant explanation for non-participation was the perception that they were already doing enough PA; they were aware of the health benefits of keeping active and believed that the trial would provide minimal benefit. The commitment required to participate was mentioned by those who expressed the desire to take on fewer commitments, those reluctant to change existing routines and where interviewee’s priorities (work, family and recreation) were given priority over pursuit of PA. Some expressed concerns about lengthy trial duration and uncomfortable trial equipment.

In terms of positive trial features, interviewees supported the focus on walking over other PA for their age group and the involvement of general practice (family practice).


Main findings

The study achieved a good recruitment rate for a primary care PA trial [7, 8, 19, 20], in a relatively affluent white population. Within this context, participants were more likely to come from affluent postcodes and be female, but being invited as an individual or as part of a couple did not affect response. Non-participants completing a survey were less likely than participants to report health problems and more likely to report being physically active, suggesting appropriate trial self-selection. This suggests that primary care recruitment could encourage those with more illnesses and primary care contact to join PA trials and fits with recommendations to improve recruitment of older people into research, particularly clinical trials [21]. The qualitative results supported the survey finding that some non-participants thought they were already sufficiently active, whilst physical symptoms, depression, time restraints, trial equipment and duration were important barriers to participation for others.

Study strengths and limitations

The main strength was the mixed methods approach of the study, with the ability to examine routinely collected demographic data on all those invited to participate, supported by more detailed data on health and PA levels of non-participants completing a survey and interview data from a purposively selected sample. It is difficult to obtain more than demographic information on non-participants [6, 9, 10], so any information is valuable from a public health perspective for exploring reasons why older people do not want to participate in PA interventions. Approximately 50% of patients either participated in the trial or the survey, confirming the value of this work. However, we cannot assume that reasons given by survey responders or by the small group of interviewees, apply to all trial non-participants; indeed whilst those agreeing to be interviewed were similar on most measures to those not agreeing, they reported higher PA levels. We were limited in the socio-economic measures assessed: only postcode and therefore IMD score [15] for all non-participants; only receipt of an occupational pension for those non-participants responding to the questionnaire. A further limitation was that the BMI of non-participants was calculated from self-reported height and weight, whereas these were objectively measured in participants. This could have led to under-reporting of BMI in non-participants, inflating the difference between participants and non-participants.

Comparison with other studies

Our recruitment rate of 30% compares well to other primary care physical activity interventions in this age group: 6% [7], 14% [20], 17% [19], 35% [8], reflecting the relatively affluent setting. Participants were more likely than non-participants to report having a limiting longstanding illness, and one or more chronic diseases (and a tendency, although not statistically significant, to suffer pain and to be overweight or obese) supporting work which found that those with a greater disease history and primary care contact were more likely to participate in primary care PA studies [9, 12] and refuting a ‘healthy volunteer effect’ [11]. Participants reported being less active and having lower walking speeds than the non-participants surveyed, consistent with their poorer physical health. This contrasts with our previous work where participants reported more PA [9]. However, that was an observational study, objectively measuring usual PA, and may have attracted those interested in PA. The current study required commitment to increase PA levels over 3–12 months [13], so those who felt they were sufficiently active may have been less likely to participate.

The interviews provided insight into perceived barriers to PA trial participation. Already considering themselves sufficiently active was a common reason for non-participation, though this may be due to higher self-reported PA levels in those who agreed to be interviewed and an overestimation of what they actually did [6, 22]. However, several interviewees confirmed that they were not physically active. Despite reporting an understanding of health benefits, their health concerns impeded them from exercising. Current poor health, including joint pain, as well as psychological factors such as depression, fear of falling and low energy were mentioned as reasons for not participating in PA, consistent with other work [6]. These findings have implications for primary care-based trials, suggesting that patients need tailored information concerning symptom management, highlighting safety and joint protection and evidence that PA can be beneficial and may alleviate painful joints [23]. Furthermore, there is a need to emphasise mental health benefits, so that a perceived barrier to exercise may become a potential benefit [24].

In common with previous studies [25, 26], lack of time was a common reason for non-participation. This was linked to work and recreational commitments, in addition to ‘slowing down’ in retirement, taking things at a leisurely pace. Although interviewees acknowledged that no programme could accommodate everyone, juggling competing responsibilities such as work and family was a barrier. Similar to previous findings [27], some interviewees cited long working hours and related fatigue as reasons for finding exercise difficult to fit in. The majority talked about the importance of maintaining a balance between work and leisure, and the possible disruption caused by increased PA. A change in emphasis is needed to ensure that older people understand the importance of exercising, and recognise that exercise can be pleasurable. These qualitative findings illustrate the importance of tailoring PA to match individual interests when designing interventions [28]. Whilst this was an important feature of our intervention, it could have been emphasised more in recruitment materials, pre-empting potential barriers.

A reluctance to go out in the evening and to go out alone prevented some from participating, as highlighted previously [6]. Trial invitations were staggered over a year, and those approached over winter were discouraged by seasonal factors and fear of falling. This highlights the importance of safety and confidence in PA and the need to address self-efficacy, which is positively related to PA engagement by older adults [29]. Organised group exercise within PA interventions may enable participants to meet others of a similar fitness level and may reduce safety concerns [30]. However, interviewees in our study supported walking as the best choice of activity for this age group and primary care as an appropriate venue for the intervention, with practice nurse support, and this model has been successful previously [31]. Outdoor walking interventions in primary care could usefully recruit in the spring or summer, building new habits before the weather deteriorates.


This mixed-method approach enabled a greater understanding of factors influencing older adults’ participation in PA studies. The quantitative comparisons showed some selection bias into the trial, with participants more likely to be female and living in less deprived areas. However, participants had more health problems and lower activity levels than non-participants who completed the survey, suggesting appropriate trial selection in a general practice population. Interviews with a small sample of non-participants revealed complex interacting physical, psychological and environmental factors underpinning the decision against trial participation. PA promotion needs to raise awareness of both physical and mental health benefits, whilst addressing physical symptoms and lack of confidence. To improve trial participation and uptake of practice-based PA endeavours, the needs of older adults should be addressed at recruitment.



Physical activity


National Health Service


General Practice Physical Activity Questionnaire


Odds Ratio


Confidence Interval.


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This paper presents independent research funded by the National Institute for Health Research (NIHR) under its Research for Patient Benefit Programme (Grant Reference Number PB-PG-0909-20055). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. The funding body was not involved in the study design, collection of data, analysis and interpretation of data, writing of the manuscript or the decision to submit the manuscript for publication. We would like to thank the three general practices who supported this study (Sonning Common Health Centre, Oxfordshire, United Kingdom and Balmore Park Surgery and Priory Avenue Surgery, Reading, Berkshire, United Kingdom) and all the patients who participated.

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Correspondence to Christina Victor.

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The authors declare that they have no competing interests.

Authors’ contributions

TH, DC and CV conceived the idea for the PACE-Lift study. TH, DC, CV, SK, AW, SI, UE, PW, CB, MU and FA participated in the design of the study, including the idea of a comparison of participants and non-participants. CV, AW, TH and AR designed the qualitative aspects of the study. AR carried out all the non-participant interviews and qualitative analyses. EL carried out the statistical comparisons between participants and non-participants. All the authors have read and approved the final manuscript.

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Rogers, A., Harris, T., Victor, C. et al. Which older people decline participation in a primary care trial of physical activity and why: insights from a mixed methods approach. BMC Geriatr 14, 46 (2014).

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