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The quality of life in patients treated for rectal cancer

  • M Mangiapane1Email author,
  • EV Bonafede1,
  • G Di Carlo1,
  • C Lo Piccolo1,
  • M Vitrano1 and
  • G Diana
BMC Geriatrics201111(Suppl 1):A27

https://doi.org/10.1186/1471-2318-11-S1-A27

Published: 24 August 2011

Background

The aim of this study is to investigate the quality of life (QOL) in patients treated surgically for rectal cancer. We will evaluate different surgical treatments, complications, presence and absence of a protective or definitive stoma and how this can influence the patient’s quality of life.

Materials and methods

We have evaluated 69 consecutive patients (39 male and 30 female) operated for rectal cancer in our ward. The preoperative investigation includes, according to guidelines for CRC treatment: pancolonscopy, chest radiography and a CT scan of the abdomen. The most appropriate surgical treatment was chosen depending on the results of the preoperative study (Table 1).

Table 1

 

n

%

Male

39

55

Female

30

45

Median age (years)

68,6

45-92

A standard questionnaire investigating the quality of life was administered to all the patients in the preoperative time (t0), in the early postoperative time(t1) and 3 (t2), 6 (t3), 9 (t4) and 12 (t5) months after the operation. Our questionnaire, the same as EORTC QLQ-C30 [1], QLQ-C38 [2] and SF-36 [3], is composed of the items described in Table 2.

Table 2

Questionnaire items

Age

Staging

Surgical treatment

Presence of stoma

Resume of non-working activity

Body functions

Emotional functions

Sexual functions

Social relations

Global QOL

Results

All the patients enrolled in the study answered our questionnaire. 31 of the patients underwent anterior resection of the rectum with total mesorectal excision(ARR), 24 underwent lower anterior resection (Low ARR), 9 underwent ultra-low anterior resection (Ultra-low ARR), 1 underwent Hartmann resection, 1 underwent abdominoperineal resection sec. Miles and 3 patients were treated by endoscopical resection (Table 3).

Table 3

Surgical Treatment

n

%

ARR

31

45

Low ARR

24

34.8

Ultra-low ARR

9

13

Others

5

7.2

A temporary stoma was made in 32 patients, and a definitive one in 2 patients. The stoma was made only in the patients with an elevated risk of anastomotic leakage. The overall complication rate was 20.2%, interesting 14 patients of the total as described in the table 4.

Table 4

 

N° patients

%

Anastomotic leakage

10

14.4

Fistula

3

4.3

Anastomotic stenosis

1

1.4

Total

14/69

20.2

The patients, in particular those with stoma, have a decrease of the QOL global index in respect to self image and social life. In t2, t3, t4, t5 the patients have a gradual improvement of their QOL although the patients with stoma always present a lower score (Fig. 1).

1

Conclusions

The perception of quality of life is a dynamic reality that changes according to the length of time we evaluate the patient. Our study, in agreement with scientific literature [46], confirms that quality of life increases with time and that although rectal cancer and its surgical treatment may produce functional and psychological deficit the QOL remains elevated.

Authors’ Affiliations

(1)
U.O.C. Chirurgia Generale e Geriatrica, AOU Policlinico di Palermo

References

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Copyright

© Mangiapane et al; licensee BioMed Central Ltd. 2011

This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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