Volume 10 Supplement 1

de Senectute: Age and Health Forum

Open Access

Sporadic Parkinsonism

  • G Nicoletti1
BMC Geriatrics201010(Suppl 1):L40

https://doi.org/10.1186/1471-2318-10-S1-L40

Published: 19 May 2010

Background

Differential diagnosis of parkinsonian sindrome is a major challenge in movement disorders because at the onset there is an overlapping of signs and syntoms. From a neuropathological point of view, parkinsonism may be related to a degeneration of the nigrostriatal pathway or the neurodegenerative process may be more widespread [1, 2]. In the early course of the a disease presenting with parkinsonian symptoms, differentiation between these disorders may be difficult, [3, 4], but the clinical diagnostic criteria become more applicable during later stages. Motor symptoms (bradikynesia, tremor at rest, rigidity) may be asoociated to cognitive disfunction. Sporadic parkinsonism may be distinguished in:) Multiple system atrophy (MSA), Progressive supranuclear palsy (PSP), Corticobasal degeneration, and Lewy body dementia [3, 5, 6].

Authors’ Affiliations

(1)
Institute of Neurology, University Magna Graecia of Catanzaro

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Copyright

© Nicoletti; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd.

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