- Meeting abstract
- Open Access
Prosthetic repair of left diaphragmatic defect in an elderly patient: a rare case report
© Cimmino et al; licensee BioMed Central Ltd. 2010
- Published: 19 May 2010
- Diaphragmatic Defect
- Left Hemithorax
- Lung Hypoplasia
- Rare Case Report
- Prosthetic Repair
Partial or complete agenesis of the hemidiaphragm is a rare congenital malformation whose embryological basis is unknown. Late presentation is extremely rare and older patients are asymptomatic for a long time without developing ventilator insufficiency, because of the associated lung hypoplasia. Thus, only 7 cases of hemidiaphragmatic agenesis have been reported in adult patients.
Surgical treatment was carried out through a left subcostal laparotomy extended on the right side. The stomach, transverse colon, splenic flexure, spleen and part of the small bowel were found in the left thoracic cavity. Repair was performed with a 2-mm-tick expanded polytetrafluoroethylene soft tissue patch (Gore-tex®) that was circumferencially anchored tension free to the ribs, intercostals muscles and endothoracic fascia (Figure 1C). Postoperative chest X-rays showed good placement of the new diaphragmatic dome and the fundic air bubble in its correct position (Figure 1D). No early major or late complications were observed, and no recurrence was found at 34 months’ follow-up.
The main questions relating to the management of a large diaphragmatic defect, such as agenesis, concern when and how to operate. We employed an e- PTFE patch, which is currently used for repairing other types of wall defect. This microporous mesh possessed good biocompatibility and produces a low inflammatory and fibrous reaction with a peripheral and interstitial arrangement of collagen fibers that allows the formation of a smooth surface. This surface is able to support a continuous layer of mesothelial cells on the peritoneal surface. This mesh seems to be an adequate and satisfactory diaphragmatic substitute, which can easily be used to repair large diaphragmatic defects, ensuring the best anatomical and physiological conditions possible with only a low risk of recurrence.
This article is published under license to BioMed Central Ltd.