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Table 2 Prevalence of most common instances of potentially inappropriate prescribing among 287 people with dementia

From: Potentially inappropriate prescribing for people with dementia in ambulatory care: a cross-sectional observational study

STOPP criterion description (potential risk)

Number of patients

% of patients

Any drug prescribed beyond the recommended duration, where treatment duration is well defined.

90

31.4

Any drug prescribed without an evidence-based clinical indication.

78

27.2

PPI for uncomplicated PUD or erosive peptic oesophagitis at full therapeutic dosage for > 8 weeks (dose reduction or earlier discontinuation indicated)

75

26.0

AchEIs with a known history of persistent bradycardia (< 60 beats/min), heart block or recurrent unexplained syncope or concurrent treatment with drugs that reduce heart rate such as beta blockers, digoxin, diltiazem, verapamil (risk of cardiac conduction failure, syncope, and injury)

60

21.0

Anticholinergics/ antimuscarinics in patients with delirium or dementia (risk of exacerbation of cognitive impairment)

28

9.8

  1. AchEIs: acetylcholinesterase inhibitors; BP: blood pressure; PPI: proton pump inhibitor; PUD: peptic ulcer disease; STOPP: Screening Tool of Older Persons Potentially Inappropriate Prescriptions