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Table 1 Weighted baseline characteristics of participants from 2011 to 2014 NHANES

From: Chronic kidney disease and cognitive performance: NHANES 2011–2014

 

CERAD test

DSST

Animal Fluency test

Characteristic

Overall, N = 2234 (100%)1

Low cognition, N = 715 (26%)1

Normal cognition, N = 1519 (74%)1

p value2

Low cognition, N = 900 (26%)1

Normal cognitionN = 1334 (74%)1

p value2

Low cognition, N = 945 (32%)1

Normal cognition, N = 1289 (68%)1

p value2

Age (years)

   

< 0.001

  

< 0.001

  

< 0.001

60–69

1,144 (53%)

271 (32%)

873 (61%)

 

364 (33%)

780 (61%)

 

425 (38%)

719 (61%)

 

70–79

614 (27%)

212 (33%)

402 (25%)

 

280 (35%)

334 (24%)

 

276 (34%)

338 (24%)

 

80+

476 (20%)

232 (34%)

244 (14%)

 

256 (33%)

220 (15%)

 

244 (28%)

232 (16%)

 

Sex (female)

1,142 (54%)

283 (44%)

859 (57%)

< 0.001

380 (48%)

762 (56%)

0.010

487 (54%)

655 (53%)

0.9

Ethnicity

   

0.004

  

< 0.001

  

< 0.001

Non-Hispanic White

1,117 (81%)

347 (77%)

770 (82%)

 

321 (65%)

796 (87%)

 

365 (70%)

752 (86%)

 

Non-Hispanic Black

493 (7.4%)

155 (8.3%)

338 (7.1%)

 

274 (16%)

219 (4.5%)

 

271 (13%)

222 (4.8%)

 

Other Hispanic

225 (3.5%)

90 (5.5%)

135 (2.8%)

 

135 (8.2%)

90 (1.8%)

 

114 (5.7%)

111 (2.5%)

 

Other/multiracial

207 (4.8%)

51 (4.4%)

156 (4.9%)

 

62 (4.3%)

145 (5.0%)

 

112 (7.2%)

95 (3.7%)

 

Mexican American

192 (3.2%)

72 (4.5%)

120 (2.8%)

 

108 (6.8%)

84 (2.0%)

 

83 (4.4%)

109 (2.7%)

 

Education attainment

   

< 0.001

  

< 0.001

  

< 0.001

high education

1,183 (64%)

270 (47%)

913 (70%)

 

275 (37%)

908 (73%)

 

372 (46%)

811 (72%)

 

low education

1,051 (36%)

445 (53%)

606 (30%)

 

625 (63%)

426 (27%)

 

573 (54%)

478 (28%)

 

PIR

3.17 (1.58)

2.54 (1.51)

3.40 (1.54)

< 0.001

2.24 (1.43)

3.50 (1.49)

< 0.001

2.61 (1.52)

3.43 (1.53)

< 0.001

BMI (kg/m2)

29.0 (6.1)

28.6 (5.7)

29.1 (6.2)

0.3

28.6 (6.1)

29.1 (6.1)

0.2

29.0 (6.4)

29.0 (5.9)

0.7

Waist circumference (cm)

102 (15)

103 (14)

102 (15)

0.6

102 (15)

103 (15)

0.7

103 (15)

102 (14)

> 0.9

Smoking status

   

> 0.9

  

0.004

  

0.2

Current

287 (11%)

100 (11%)

187 (11%)

 

144 (14%)

143 (10%)

 

137 (14%)

150 (10%)

 

Former

854 (39%)

276 (40%)

578 (39%)

 

354 (44%)

500 (38%)

 

350 (39%)

504 (39%)

 

Never

1,093 (49%)

339 (48%)

754 (50%)

 

402 (42%)

691 (52%)

 

458 (47%)

635 (50%)

 

Alcohol drinking

1,560 (74%)

495 (70%)

1,065 (76%)

0.009

586 (66%)

974 (77%)

< 0.001

618 (68%)

942 (77%)

< 0.001

Hypertension

1,373 (58%)

456 (64%)

917 (56%)

0.050

604 (66%)

769 (55%)

< 0.001

631 (64%)

742 (55%)

< 0.001

Diabetes

528 (19%)

189 (23%)

339 (18%)

0.058

261 (27%)

267 (17%)

< 0.001

262 (25%)

266 (17%)

< 0.001

uACR

46 (297)

62 (291)

40 (299)

0.008

97 (440)

28 (225)

< 0.001

79 (433)

31 (205)

< 0.001

eGFR (ml/min/ 1.73m2)

73 (19)

69 (21)

74 (18)

< 0.001

69 (23)

74 (18)

0.001

70 (22)

74 (17)

0.001

CKDgroup

   

< 0.001

  

< 0.001

  

< 0.001

No CKD

1,452 (67%)

408 (57%)

1,044 (71%)

 

500 (54%)

952 (72%)

 

550 (58%)

902 (72%)

 

Stages 1–2

259 (9.1%)

98 (11%)

161 (8.5%)

 

137 (13%)

122 (7.6%)

 

123 (10%)

136 (8.5%)

 

Stages 3–5

523 (24%)

209 (33%)

314 (20%)

 

263 (33%)

260 (20%)

 

272 (32%)

251 (20%)

 
  1. 1Median ± standard deviation for continuous; n (%) for categorical
  2. 2Chi-squared test with Rao & Scott’s second-order correction
  3. p < 0 0.05 is written in bold letters