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Table 2 Tool properties

From: Tools to measure barriers to medication management capacity in older adults: a scoping review

Tools

Purpose

Number of Items

Scoring scale

Administration time

Type of instrument

Type of Medication regimen used

Medication management skill assessed

Psychometric properties -Study

Validity

Reliability

Content

Construct

Inter-rater

Test-retest

Internal consistency

Physical + Cognition + Sensory + Motivation

ManageMed Screening (MMS) [59]

To quickly determine if someone can handle a moderately difficult medication routine

33 item

0-39

15-20 minutes

Performance-based

Simulated medication regimen

Read Rx label, recall information, open/close vials, perform calculations, organize pillbox

[59]

+

Neurocognitive function (Cognistat)

(Pearson Correlation Coefficient of .696)

(0.86-

0.96)

 

0.89

Self-Medication Risk Assessment Tool (RAT) [34]

To assess elderly patients' needs for additional support in managing their medicines

13 item

0-26

5-20 minutes

Performance-based

Simulated and patient’s medication regimens

Read Rx labels, open different medication packaging, manipulate with 5 ml spoon and eye or ear drop bottles

[67]

+

Patient’s

comprehension and

dexterity of

handling the

medications

  

(≥0.79)

Cognitive Screen for Medication Self-Management (CSMS) [30]

To assess the sensory and cognitive constructs associated with medication adherence

8 item

15

NR

Performance-based

Simulated medication regimen

Bottle opening, label reading, clock reading, dose

calculations, arrangement time, study time, immediate recall, delayed, recall, cued

recall, prospective memory and dose planning

[30]

+

Cognitive status and age

  

-0.08-0.84

Physical + Cognition + Sensory + Environmental

Medication Management Ability Assessment (MMAA) [48, 56]

To assess geriatric mental health patients’ ability to independently manage medications

4 item

0-25

45-60 minutes

Performance-based

Simulated medication regimen

Recall information, describe full regimen,

open/close, remove the dose from vials,

differentiate tablet by color

[68]

+

Cognitive function

(neuropsychological

l battery test)

Adherence

 

0.96

 

Self-Medication Assessment Tool (SMAT) [22, 29, 61]

To screen for medication self-management deficits in older adults and to facilitate targeted interventions

44 item

Multiple scale

45-60 minutes

Performance-based

Patient's own medication regimen Simulated medication regimen

Read Rx labels, recall information, interpret medication instructions, open vials, remove tablets form packaging,

differentiate tablets by color, organize pillbox

[69]

+

Cognitive function (MMSE, CDT, CCT), Medication regimen complexity, Self-reported adherence

+(≥0.79)

+(≥0.83)

+(≥0.81)

Physical + Cognition + Motivation + Environmental

HOME-Rx revised [20]

To assess ability to manage medication routines in context, identify risk factors for medication management problems, and identify the environmental barriers influencing medication management ability

4 subscales

Multiple scale

25 to 35 minutes

Performance-based

Patient's own medication regimen

Knowledge of medications,

Recall information, maniple of medication bottles

and/or syringe, and calculate

medication doses,

storing and

retrieving pills; reading labels; verbalizing the dosage instructions, special instructions, and purpose; following dosing

directions correctly and recognizing when one has missed doses; opening containers; setting up medications; taking

out medications; and physically administering medications.

[20]

+

PASS (positively correlated with the

HOME–Rx Performance subscale (r = .57, p < .001) and Safety

subscale (r = .49, p < .001))

MedMaIDE (negatively

correlated with the HOME–Rx Performance subscale (r = −.69,

p < .001) and positively correlated with the

HOME–Rx Barriers subscale (r = .70, p < .001)) , I–HOPE Assist

  

.87 to 1.00

Medication Management Instrument for Deficiencies in the Elderly (MedMaIDE) [20, 35]

To identify the deficiencies in older adults’ ability to take their medication at home.

20 item

0-13

30 minutes

Performance-based

Patient's own medication regimen

Medication knowledge (name all drugs and describe full regimen including indication, rout of administration, dose and time), Medication taking ability (filling a glass of water, sip enough water, open bottles/vials, remove dose from package, and demonstrate admiration method for oral and non-oral dosage form),Knowledge about ongoing supplies (identify existing refills, name of pharmacy or physician office, and available resources)

[70]

+

Cognitive function

(MMSE)

Functional status

(ADL)

Med. adherence

(pill count)

0.74

0.93

0.71

Physical + Cognition+ Motivation

Show Back [66]

To assess older adult medication self-management proficiency

5 item

0-100

22 minutes

Performance-based

Simulated medication regimen

Identify medications, explaining the indication, organizing pillbox, describing the administration process for injectables and inhaled medications, describing the timing of doses

[66]

+

Medication Discrepancy Tool (MDT)

0.83-1

  

MedTake test [53]

To quantify seniors’ ability to take oral

drugs safely, standardize the brown bag

review

4 item

0-100

30-45 minutes

Performance-based

Patient's own medication regimen

Identify meds & recall med names, open

bottles/vials & remove dose from package, state

indication, food/water congestion, and timing

[53]

+

Cognitive function

(MMSE)

Educational level

   

HOME-Rx [48]

To assess an older adult’s ability to manage medication routines in the home and to identify at-risk behaviors by home health occupational therapists

16 item

1-16

30-45 minutes

Performance-based

Patient's own medication regimen

Knowledge of medications, recall information, maniple of medication bottles and/or syringe, and calculate medication doses

[48]

+

Cognitive function

(MoCA)

MMC (MangeMed)

  

.87 to 1.00

Hopkins Medication Schedule (HMS) [58, 59]

To test older adults’ ability to understand and implement a routine prescription medication

2 item

0-11

15-30 minutes

Performance-based

Simulated medication regimen

Read Rx labels, comprehend medication

regimen, plan a schedule for meds regimen,

open & close vails, remove dose from vials,

organize pillbox.

[71]

+

Cognitive function

(MMSE)

Functional status

(IADL)

 

0.38

 

Cognition + Sensory + Motivation

Performance Assessment of Self-care Skills (PASS-IADL) [48]

To measure occupational performance of daily life tasks

26 (four domains)

NR

1.5-3 hour

Performance-based

NA

NA

[72]

+

 

0.29-0.43

0.82-0.97

0.94-0.96

Physical + Cognition

Drug Regimen Unassisted Grading Scale (DRUGS) [15, 29, 49, 59]

To assess Medication self-management ability

4 item

0-100

5-15 minutes

Performance-based

Patient's own medication regimen

Identification: showing the appropriate

medications, access: opening the appropriate containers,

dosage: dispensing the correct number per dose, and

timing: demonstrating the appropriate timing of doses

[73]

+

Cognitive function

(MMSE)

Functional status

(ADL & IADL)

Self‐reported MMC

Health literacy

 

0.83

0.81

Cognition + Motivational

Short Test of Functional Health Literacy in Adults (S-TOFHLA) [41]

To measure patients’ ability to read and understand the things they commonly encounter in the health care setting using actual materials like pill bottles and appointment slips

4 Numeracy items and 2 prose passages

0-100

12 minutes

Performance-based

Patient's own medication regimen

 

[74]

+

REALM

  

0.68-0.97

Test of Functional Health Literacy in Adults (TOFHLA-R) [45, 46, 65]

To measure the functional health literacy of patients.

50-item reading comprehension and 17-item numerical ability test

0-50

22 minutes

Performance-based

Patient's own medication regimen

Reading comprehension and numeracy

[75]

+

REALM

WRAT-R

 

0.92

0.98

Comprehensive Health Activities Scale (CHAS) [45, 46]

To measure health literacy skills

45 item

0-100

60 minutes

Performance-based

Simulated medication regimen

organizing and dosing medication

[76]

+

TOFHLA and the NVS, REALM and the MMSE

 

> 0.80

 

Functional, communicative and critical health literacy scales

(FCCHL) [62]

Three newly developed scales for measuring functional, communicative, and critical HL among patients with type 2 diabetes in order to propose a measure of HL

14 item

4-point Likert scale ranging from ‘‘never’’ (1) to ‘‘often’’ (4)

NR

Self-reported

Patient's own medication regimen

NR

[77]

+

  

0.67-0.72

0.87

Motivation + Environmental

Long-Term Medication Behavior Self-Efficacy Scale (LTMBSES) [14]

To measures self-efficacy in relation to

medication compliance

22 item

Multiple scales

NR

Self reported

NA

NA

[78]

+

Various levels of adherence

  

0.88

Self-efficacy for Appropriate Medication Use Scale (SEAMS) [15, 38, 42, 44, 54]

To assess self-efficacy for appropriate medication use

21 item

21-63

5-10 minutes

Self-reported

Patient's own medication regimen

NR

[15, 38, 42, 44, 54]

+

REALM

Various disease

Various literacy levels

 

0.62

0.90

Cognition

Mini-Mental State Examination (MMSE) [31, 36, 39, 47, 49, 51, 53, 64]

To check for cognitive impairment (problems with thinking, communication, understanding and memory)

11 item

0-30

10 minutes

Performance-based

NA

Cognitive ability to manage medications

[79]

+

Mattis Dementia Rating Scale

Wechsler Adult Intelligence Test,

Functional Independence Measure, Montgomery Asberg Depression Rating Scale .

Zung Depression Scale.

0.69

0.96

0.96

Wisconsin Card Sorting Test (WCST) [31]

To assess abstract reasoning ability and the ability to shift cognitive strategies in response to changing environ-mental contingencies and also considered a measure of the executive functions.

14 item

 

12–20 minutes

Performance-based

NA

Cognitive ability to manage medications

[80]

+

   

0.93

Digit Span Backward (DSB) [31]

To assess working memory

8 item

0-16

Less than 5 minutes

Performance-based

NA

Cognitive ability to manage medications

[81]

+

Wechsler Adult Intelligence Scale

 

0.76-0.95

 

California Verbal Learning Test (CVLT) [31]

To assesses encoding, recall and recognition

16 item

 

30 minutes

Performance-based

NA

NA

[82]

+

  

0.80–0.84

 

Mini-Cog [33, 40]

To evaluate cognition in older adults

4 item

0-5

3 minutes

Performance-based

Pillbox

Read Rx labels, interpret medication instructions, organize pillbox

[83]

+

Abbreviated mental test score (AMTS), the Geriatric Depression Scale

0.76

0.86

0.83

Medi-Cog [33, 40]

To assess patients’ ability to fill their own prescribed medications into a pillbox

3 item

0-10

7-8 minutes

Performance-based

Pillbox

Read Rx labels, interpret medication instructions, organize pillbox

[84]

+

Cognitive function

Correctly filled

pills

   

Medication-Transfer Screen (MTS) [33, 40]

To assess patients’ ability to fill their own prescribed medications into a pillbox

4 item

5

5 minutes

Performance-based

Pillbox

Read Rx labels, interpret medication instructions, organize pillbox

[84]

+

Cognitive function Correctly filled pills

   

Montreal Cognitive Assessment (MoCA) [37, 65]

It assesses different cognitive domains: attention and concentration, executive functions, memory, language, visuoconstructional skills, conceptual thinking, calculations, and orientation

30 item

0-30

10 minutes

Performance-based

NA

NA

[85]

 

Age, educational levels, economic status, and sex, MMSE

 

0.92

0.82

Short Blessed Test (SBT) [37]

This test addresses cognitive concerns in the areas of orientation, memory, and

concentration.

6 item

0 – 28

5-10 minutes

Performance-based

NA

NA

[86]

 

MMSE

  

0.52-0.58

Trail-Making Test (TMT) [24, 37, 51]

To assess executive function

25 item

Part A- 1-39 sec

Part B-1-91 sec

5-10 minutes

Performance-based

NA

NA

[87]

 

Category Test (CAT), Wisconsin Card Sort Test (WCST), Paced Auditory Serial Addition Task (PASAT), Visual Search and Attention Test (VSAT).

 

Part A-0.78 Part B- 0.67

 

Measure of Drug Self Management (MeDS) [52]

An assessment of medication self-management skills

NR

0-12

NR

Self-reported

Patient's own medication regimen

NR

[52]

+

Morisky Medication Adherence Scale and relevant clinical measures (HbA1c, blood pressure, and low-density lipoprotein cholesterol)

  

0.72

Fuld Object-Memory Evaluation (FOME) [63]

To assess memory

10 item

0-10

15 minutes

Performance-based

NA

NA

[88]

+

  

0.71

0.84

Sensory

National

Eye Institute Visual Function

Questionnaire -25

(NEI VFQ–25) [43, 50]

To measures the dimensions of self-reported vision-targeted health status that are most important for persons who have chronic eye diseases.

25+1 item

0-100(Multiple scale)

10 minutes

Self-reported

NA

NA

[89]

+

Various eye disease

51-item NEI VFQ

  

0.71-0.85

Daily Living Tasks associated with Vision (DLTV) [16]

To assess functional impairment among patients

with age-related macular degeneration (AMD)

24 item

0-100

6-10 minutes

Self-reported

NA

NA

[90]

+

   

0.97

Pelli-Robson letter sensitivity chart (PR test) [58]

To measures a patient's contrast sensitivity (CS) by finding the lowest contrast letters he/she can read correctly

NR

NR

NR

Self-reported

NA

NA

 [91]

     

Randot Circles [58]

To test the patient depth perception along with normal stereo vision.

NR

NR

NR

Self-reported

NA

NA

      

Early Treatment Diabetic Retinopathy Study eye chart (ETDRS) [58]

To measure visual acuity

5 letters of equal difficulty on each row, with standardized logarithmic spacing between letters and rows: a total of 14 lines (70 letters)

NR

NR

Performance-based

NA

NA

[91]

 

Accuracy-0.12±0.14

 

Test -retest variability-0.23±0.17

 

Whisper test [53]

To assess hearing

6 steps

Threshold for hearing

impairment

<50% correct

5 minutes

Self-reported

NA

NA

[92]

 

Sensitivity (%; 95% CI) 100 (96-100) ,)

Specificity (%; 95% CI) 87 (80-92

   

Motivation

The Newest Vital Sign (NVS) [46, 54, 61]

To identify patients at risk for low health literacy.

6 item

0-6

3 minutes

Performance-based

Patient's own medication regimen

Read Rx labels, interpret medication

instructions

[93]

+

TOFHLA

  

0.76

Rapid Estimate of Adult Literacy in Medicine (REALM) [32, 35, 38, 45, 46, 55, 60]

To assess an adult patient's ability to read common medical words and lay terms for body parts and illnesses

7 item

0-66

2-3 minutes

Performance-based

NA

NA

[94]

+

Peabody Individual Achievement Test-Revised (PIAT-R)

Wide Range Achievement Test-Revised (WRAT-R),

Slosson Oral Reading Test-Revised (SORT-R)

 

0.99

0.97

Medication Administration Self-Efficacy Scale (MASES) [65]

To identify levels of self-efficacy, self-care, trust, levels of support from the community and organizations, and satisfaction levels related to self-administration of medications

26 item

0-3

NR

Self-reported

Patient's own medication regimen

NA

[65]

+

   

0.95

Martin and Park Environmental Demands Questionnaire (MPED) [14]

To measure two dimensions of environmental demand: (1)

busyness and (2) routine

13-item

Likert scale 1 through 5.

5-10 minutes

Self-reported

NA

NA

[95]

+

Age

Household size

Medication-taking errors. (External validity)

  

0.88 for the busyness scale and 0.74 for the routine scale

Environmental

Medication-Specific Social Support Questionnaire (MSSS) [44]

To identify how often participants received help for their medication taking over a three-month period

8 items

0-4

NR

Self-reported

NA

NA

[96]

+

Various diseases, drugs

  

0.92

Multidimensional Scale of Perceived Social Support (MSPSS) [57]

To assess an individual’s perception of the social support he or she receives from family, friends and significant others

12 item

7-point Likert type scale

5-10 minutes

Self-reported

NA

NA

[97]

+

  

0.91

0.95

Perceived Social Support from Friends (PSS-Fr) and the Perceived Social Support from Family (PSS-Fa) [14]

To measure the

extent to which an individual perceives that his/her needs are fulfilled by friends and

family

20 item

0-20

NR

Self-reported

NA

NA

[98]

+

Various symptoms of distress and psychopathology, mood states

  

0.88 for PSS-FR and 0.90 for PSS-FA