AD (n = 145) Mean ± SD | Controls (n = 51) Mean ± SD | t(194) or χ2 | p-values | |
---|---|---|---|---|
Demographic and clinical data | ||||
Male/Female | 61/84 | 20/31 | 0.13 | 0.722 |
Age, y | 71.51 ± 8.31 | 64.71 ± 11.02 | 4.60 | <0.0001 |
BMI | 25.88 ± 3.96 | 27.65 ± 4.75 | −2.61 | <0.01 |
MMSE | 16.92 ± 5.39 | 27.51 ± 1.89 | −13.72 | <0.0001 |
Muscle Strength and Muscle Mass | ||||
HGS | 17.47 ± 7.22 | 21.78 ± 8.30 | 13.93a | <0.0005 |
SMI | 9.73 ± 1.59 | 9.98 ± 1.75 | 0.01a | 0.938 |
SM | 26.38 ± 5.31 | 25.75 ± 6.27 | 0.17a | 0.683 |
ASM | 20.85 ± 4.08 | 19.88 ± 4.10 | 0.07a | 0.790 |
ASM/height2 | 7.54 ± 0.97 | 7.88 ± 1.28 | 0.00a | 0.956 |
MQI | 0.70 ± 0.29 | 0.84 ± 0.28 | 11.33a | <0.001 |
Sarcopenia diagnostic algorithms | ||||
EWGSOP1, Low muscle mass (%) | 37 (25.5%) | 9 (17.6%) | 1.30 | 0.254 |
EWGSOP1, Low muscle strength (%) | 119 (82.1%) | 29 (56.9%) | 12.96 | <0.0005 |
EWGSOP1, Sarcopenia (%) | 34 (23.4%) | 6 (11.8%) | 3.17 | 0.075 |
EWGSOP2, Low muscle strength (%) | 95 (65.5%) | 18 (35.3%) | 14.12 | <0.0005 |
EWGSOP2, Low muscle mass (%) | 6 (4.1%) | 3 (5.9%) | 0.26 | 0.609 |
EWGSOP2, Sarcopenia (%) | 5 (3.4%) | 1 (2.0%) | 0.28 | 0.596 |
FNIH, Low muscle strength (%) | 91 (62.8%) | 18 (35.3%) | 11.53 | <0.001 |
FNIH, Low muscle mass (%) | 18 (12.4%) | 10 (19.6%) | 1.59 | 0.207 |
FNIH, Sarcopenia (%) | 14 (9.7%) | 3 (5.9%) | 0.68 | 0.410 |