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Table 4 Comparison of overall survival between patients with chemotherapy and no-chemotherapy in specific tumor grades, stages, nodal status and progesterone receptor status using a multivariate Cox proportional hazard model

From: Adjuvant chemotherapy and survival in males aged 70 years or older with breast cancer: a population-based retrospective study

Variables

Overall Survival

Events

Hazard Ratio (95% Confidence Interval)

P a

N0 (n = 961)

613

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.790 (0.555–1.125)

0.192

N+ (n = 544)

373

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.734 (0.566–0.951)

0.019

Grade Well/Moderately n = 940)

579

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.788 (0.581–1.068)

0.124

Grade Poorly/undifferentiated n = 524)

382

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.628 (0.460–0.859)

0.004

Stage I n = 561)

351

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.644 (0.384–1.081)

0.096

Stage II n = 673)

429

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.628 (0.456–0.866)

0.004

Stage III n = 283)

218

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.696 (0.504–0.963)

0.029

PR + Stage I n = 424)

230

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.603 (0.312–1.167)

0.133

PR + Stage II n = 523)

302

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.783 (0.538–1.140)

0.202

PR + Stage III n = 192)

132

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.571 (0.372–0.875)

0.010

PR- Stage I n = 40)

31

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

1.205 (0.304–4.777)

0.791

PR- Stage II n = 55)

40

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.201 (0.051–0.792)

0.022

PR- Stage III n = 30)

25

  

No-chemotherapy

 

Reference

 

Chemotherapy

 

0.242 (0.060–0.972)

0.046

  1. aP value was adjusted by a multivariate Cox proportional hazard regression model and bold type indicates significance
  2. Note: PR: Progesterone Receptor