Adjuvant chemotherapy and survival in males aged 70 years or older with breast cancer: a population-based retrospective study

Table 3 Multivariate Cox proportional hazard model of overall survival in all patients. Note:

Variables		Overall Survival
Variables		Hazard Ratio (95% Confidence Interval)	P ^c
Race	White	Reference
	Black	0.946 (0.781–1.146)	0.570
	Other ^a	0.818 (0.622–1.077)	0.152
Marital status	Married	Reference
	Not married ^b	1.456 (1.291–1.641)	< 0.001
	Missing	1.015 (0.761–1.354)	0.921
Histology	Ductal	Reference
Histology	Other ^d	0.886 (0.778–1.009)	0.067
Grade	Well	Reference
	Moderately	1.194 (0.963–1.479)	0.106
	Poorly/undifferentiated	1.427 (1.142–1.783)	0.002
	Missing	1.330 (1.046–1.693)	0.020
Tumor size	T1	Reference
	T2	1.215 (1.057–1.395)	0.006
	T3/4	1.813 (1.448–2.270)	< 0.001
	Missing	0.608 (0.355–1.041)	0.070
Nodal status	N0	Reference
	N1	1.197 (1.021–1.403)	0.027
	N2/3	1.612 (1.317–1.973)	< 0.001
	Missing	2.350 (1.387–3.981)	0.001
Estrogen Receptor	Positive	Reference
	Negative	1.403 (0.927–2.123)	0.110
	Missing	1.223 (0.714–2.094)	0.464
Progesterone Receptor	Positive	Reference
	Negative	1.193 (0.937–1.520)	0.152
	Missing	0.855 (0.507–1.441)	0.557
Surgery approach	Breast Conserving Surgery	Reference
	Mastectomy	0.755 (0.583–0.979)	0.034
	Missing	0.814 (0.618–1.072)	0.144
Radiation status	No	Reference
Radiation status	Yes	0857 (0.736–0.997)	0.046
Chemotherapy status	No	Reference
Chemotherapy status	Yes	0.822 (0.682–0.991)	0.040

^a Other includes American Indian/Alaskan native and Asian/Pacific Islander and Unknown
^b Not married includes divorced, separated, single (never married), unmarried or domestic partner, and widowed
^cP value was adjusted by a multivariate Cox proportional hazard regression model and bold type indicates significance
^d Other represents all pathological types other than invasive ductal breast cancer, including invasive lobular carcinoma, medullary carcinoma, mucinous carcinoma, intraductal papilloma, papillary carcinoma, tubular carcinoma, and so on

ISSN: 1471-2318