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Table 4 Estimates from linear mixed-effects models for LS7 individual metrics for old−old individuals

From: Change in cardiovascular health and rate of cognitive decline in older adults: a 15-year population-based study

Cognitive test

Worse

Improved

Beta

P value

95% CI

Beta

P value

95% CI

Smoking

      

episodic memory

−0.10

0.142

−0.24, 0.03

0.01

0.676

−0.05, 0.07

semantic memory

0.07

0.557

−0.17, 0.32

−0.02

0.723

−0.10, 0.07

verbal fluency

−0.16

0.016

−0.29, −0.03

0.00

0.882

−0.07, 0.06

perceptual speed

−0.19

0.014

−0.34, −0.04

0.00

0.947

−0.07, 0.08

global cognition

−0.14*

0.010

−0.24, −0.03

0.00

0.892

−0.05, 0.05

Diet

      

episodic memory

−0.01

0.579

−0.04, 0.02

−0.01

0.644

−0.03, 0.02

semantic memory

−0.02

0.481

−0.07, 0.03

0.04

0.078

0.00, 0.08

verbal fluency

−0.01

0.455

−0.05, 0.02

−0.01

0.722

−0.03, 0.02

perceptual speed

0.01

0.764

−0.04, 0.05

0.01

0.711

−0.03, 0.04

global cognition

0.00

0.813

−0.03, 0.02

0.01

0.408

−0.01, 0.03

Physical activity

      

episodic memory

−0.02

0.131

−0.05, 0.01

0.02

0.303

−0.02, 0.05

semantic memory

−0.04

0.044

−0.08, 0.00

−0.03

0.183

−0.08, 0.02

verbal fluency

−0.02

0.174

−0.05, 0.01

−0.01

0.417

−0.05, 0.02

perceptual speed

−0.05*

0.005

−0.08, −0.01

−0.02

0.234

−0.07, 0.02

global cognition

−0.03*

0.001

−0.06, −0.01

−0.01

0.310

−0.04, 0.01

Body mass index

      

episodic memory

−0.03

0.180

−0.06, 0.01

−0.03

0.067

−0.06, 0.00

semantic memory

0.02

0.423

−0.03, 0.08

0.01

0.643

−0.04, 0.06

verbal fluency

0.01

0.791

−0.03, 0.05

−0.02

0.297

−0.05, 0.01

perceptual speed

−0.02

0.516

−0.06, 0.03

0.02

0.250

−0.02, 0.06

global cognition

0.00

0.821

−0.04, 0.03

0.00

0.788

−0.03, 0.02

Blood glucose

      

episodic memory

0.00

0.705

−0.02, 0.03

−0.01

0.664

−0.05, 0.03

semantic memory

−0.02

0.410

−0.05, 0.02

−0.01

0.852

−0.06, 0.05

verbal fluency

0.02

0.104

0.00, 0.05

0.02

0.336

−0.02, 0.06

perceptual speed

0.00

0.985

−0.03, 0.03

0.01

0.606

−0.04, 0.06

global cognition

0.01

0.514

−0.01, 0.03

0.01

0.737

−0.03, 0.04

Total cholesterol

      

episodic memory

0.00

0.955

−0.04, 0.04

−0.02

0.195

−0.04, 0.01

semantic memory

−0.01

0.766

−0.06, 0.05

−0.01

0.445

−0.05, 0.02

verbal fluency

−0.02

0.292

−0.06, 0.02

0.01

0.488

−0.02, 0.03

perceptual speed

−0.04

0.096

−0.09, 0.01

0.01

0.481

−0.02, 0.04

global cognition

−0.01

0.517

−0.04, 0.02

0.00

0.846

−0.02, 0.02

Blood pressure

      

episodic memory

−0.05*

0.002

−0.08, −0.02

−0.01

0.524

−0.03, 0.02

semantic memory

−0.03

0.152

−0.08, 0.01

0.01

0.462

−0.02, 0.05

verbal fluency

−0.03

0.036

−0.07, 0.00

−0.01

0.455

−0.04, 0.02

perceptual speed

−0.04

0.032

−0.08, 0.00

0.00

0.987

−0.03, 0.03

global cognition

−0.04*

0.005

−0.06, −0.01

0.00

0.872

−0.02, 0.02

  1. Shown beta coefficients, confidence intervals, and p−values represent differences in rate of change compared to the stable LS7 group. Significant results are marked with an asterisk (*). A significance level of 0.0125 was applied for the specific domains of episodic memory, semantic memory, verbal fluency, and perceptual speed, while a value of 0.05 was used for global cognition. Analyses were controlled for age at baseline, sex, years of education, and baseline LS7