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Table 2 Multivariate Cox regression analysis of the impact of hypertension and frailty on death risk in older adults according to the different agegroups

From: Interaction between hypertension and frailty and their impact on death risk in older adults: a follow-up study

Variables

Overall (n = 1197)

60–69 years (n = 378)

70–79 years (n = 415)

≥ 80 years (n = 404)

 

HR(95%CI)

P-value

HR(95%CI)

P-value

HR(95%CI)

P-value

HR(95%CI)

P-value

Age

1.048(1.042–1.055)

< 0.001

1.077(1.049–1.106)

< 0.001

1.046(1.025–1.068)

< 0.001

0.994(0.953–1.037)

0.784

Gender

0.721(0.662–0.786)

< 0.001

0.623(0.526–0.739)

< 0.001

0.735(0.646–0.836)

< 0.001

0.850(0.720–1.003)

0.054

Education levela

 Junior high school

0.977(0.901–1.046)

0.397

0.923(0.833–1.057)

0.294

0.965(0.849–1.114)

0.326

0.933(0.877–1.366)

0.233

 Senior high school or above

0.864(0.812–1.019)

0.183

0.811(0.732–1.016)

0.109

0.852(0.766–1.021)

0.079

0.847(0.807–1.173)

0.128

 Marital status

1.371(1.219–1.543)

< 0.001

1.369(1.150–1.630)

< 0.001

1.269(1.059-–1.521)

0.010

1.632(1.107–2.405)

0.013

Hypertension and frailty statusb

 Hypertension and no frailty

1.406(1.237–1.597)

0.005

1.331(1.159–2.354)

0.021

1.594(1.113–1.744)

0.018

1.174(0.774–1.781)

0.450

 No hypertension but frailty

1.484(1.259–1.933)

< 0.001

1.345(1.052–1.721)

0.018

1.511(1.254–1.820)

< 0.001

1.223(0.948–1.578)

0.122

 Hypertension and frailty

1.792(1.642–1.957)

< 0.001

2.122(1.777–2.533)

< 0.001

1.821(1.604–2.067)

< 0.001

1.573(1.338–1.850)

< 0.001

  1. Abbreviations: FI Frailty index
  2. aPrimary school is the control group
  3. bNo hypertension and no frailty is the control group