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Table 5 The Zung Self-Rating Depression Scale scores at different time points in four groups

From: Effects of dexmedetomidine combined with etomidate on postoperative cognitive function in older patients undergoing total intravenous anaesthesia: a randomized, double-blind, controlled trial

Time points

EN1 group

n=34

ED1 group

n=31

EN2 group

n=32

ED2 group

n=35

F values

P values

t0

42.7±2.8

42.2±3.0

43.1±3.1

42.1±2.8

0.917

0.435

t1

47.9±2.4*

44.5±2.7*#$

49.2±2.6*

45.1±2.4*#$

25.639

0.000

t2

46.7±2.4*

42.5±2.1#$

47.2±3.0*

43.7±2.9*#$

23.262

0.000

t3

42.6±2.2

41.6±2.3

42.3±2.3

41.5±3.1

1.391

0.248

t4

41.5±2.7

42.56±2.7

41.8±2.9

42.1±2.8

0.633

0.594

t5

42.3±2.5

41.8±2.1

43.1±2.7

41.6±2.4

2.199

0.091

F values

37.108

5.471

36.783

9.061

—

—

P values

0.000

0.000

0.000

0.000

—

—

  1. EN1 Etomidate-remifentanil with duration of surgery less than 60min, ED1 Etomidate-remifentanil and dexmedetomidine with duration of surgery less than 60min, EN2 Etomidate-remifentanil with duration of surgery more than 60min, ED2 Etomidate-remifentanil and dexmedetomidine with duration of surgery more than 60min. t0 30 minutes before anesthesia, t1 3h after surgery, t2 8h after surgery, t3 24h after surgery, t4 48h hours after surgery and t5 72h after surgery. * p < 0.05 vs.t0, # p < 0.05 vs.EN1 and $ p < 0.05 vs.EN2