Effects of dexmedetomidine combined with etomidate on postoperative cognitive function in older patients undergoing total intravenous anaesthesia: a randomized, double-blind, controlled trial

Table 3 The Riker sedation agitation scores after extubation in four groups

Time points	Groups	n	Riker sedation agitation scores
Time points	Groups	n	1	2	3	4	5	6	7
5min after extubation	EN₁	34	0	0	2	7	13	10	2
	ED₁^*	31	0	2	9	15	4	1	0
	EN₂	32	0	0	2	6	13	8	3
	ED₂^#	35	0	1	7	16	9	2	0
	X² value	41.228
	P value	0.000
15min after extubation	EN₁	34	0	2	4	6	12	9	1
	ED₁^*	31	0	6	13	9	3	0	0
	EN₂	32	0	0	0	7	13	9	3
	ED₂^#	35	0	8	8	12	7	0	0
	X² value	59.285
	P value	0.000
30min after extubation	EN₁	34	0	2	4	9	12	7	0
	ED₁^*	31	0	10	14	6	1	0	0
	EN₂	32	0	0	0	8	14	8	2
	ED₂^#	35	0	6	10	13	6	0	0
	X² value	67.804
	P value	0.000
60min after extubation	EN₁	34	0	0	2	13	14	5	0
	ED₁^*	31	0	2	16	12	1	0	0
	EN₂	32	0	0	0	13	12	6	1
	ED₂^#	35	0	4	10	16	5	0	0
	X² value	60.015
	P value	0.000

EN₁ Etomidate-remifentanil with duration of surgery less than 60min, ED₁ Etomidate-remifentanil and dexmedetomidine with duration of surgery less than 60min, EN₂ Etomidate-remifentanil with duration of surgery more than 60min, ED₂ Etomidate-remifentanil and dexmedetomidine with duration of surgery more than 60min
^* p < 0.05 vs.EN₁, ^# p < 0.05 vs.EN₂

ISSN: 1471-2318