Table 2 Association of anticholinergic burden score and chronic polypharmacy with abnormal Timed Up and Go test
Total (n = 42,132) | Abnormal TUG (n = 15,667) | Crude OR (95% CI) | Model 1a aOR (95% CI) | Model 2b aOR (95% CI) | Model 3c aOR (95% CI) | ||
|---|---|---|---|---|---|---|---|
KABS score | 0 | 38,797 (92.1) | 14,250 (91.0) | 1 | 1 | 1 | 1 |
1–2 | 2,234 (5.3) | 937 (6.0) | 1.26 (1.15–1.37) | 1.23 (1.13–1.35) | 1.10 (0.94–1.28) | 1.09 (0.93–1.27) | |
≥ 3 | 1,101 (2.6) | 480 (3.1) | 1.13 (1.03–1.24) | 1.33 (1.17–1.50) | 1.30 (1.05–1.62) | 1.27 (1.02–1.58) | |
P for trend | < 0.001 | < 0.001 | 0.009 | 0.020 | |||
Chronic polypharmacy | No | 39,148 (96.0) | 14,976 (95.6) | 1 | 1 | 1 | 1 |
Yes | 1,632 (4.0) | 691 (4.4) | 1.19 (1.07–1.31) | 1.18 (1.06–1.30) | 1.08 (0.91–1.29) | 1.05 (0.88–1.25) |