Fig. 2

Inflammatory markers in frail vs. non-frail group. The bar charts show the differences in the concentration of inflammatory markers in the frailty groups, for; A.) CRP, B.) IL-6, C.) IGF-1, D.) cystatin C, E.) cathepsin S, and F.) Gp-acetyls. The data are an illustration of supplementary Table 3a and show significantly higher levels of IL-6 cystatin C, cathepsin S, and Gp-acetyls in the frail group, compared to the non-frail group. There were no significant differences in CRP or IGF-1 between the two groups. The cut-off value to be categorized as “frail” was set to ≥ 0.25. CRP levels ≥ 50 were excluded from the analysis. * P<0.05, **P<0.001. CRP, C-reactive protein; IL-6, interleukin 6; IGF-1, insulin growth factor 1; Gp-acetyls, Glycoprotein acetyls