Early postoperative neurocognitive complications in elderly patients: comparing those with and without preexisting mild cognitive impairment– a prospective study

Table 4 Patient progress postsurgery

Variables	Non-MCI (n = 56)	MCI (n = 223)	P
ICU admission			0.072
Yes	31 (55.4%)	93 (41.7%)
No	25 (44.6%)	130 (58.3%)
ICU stay^a (days)	2 (2–3)	3 (2–4)	0.407
Postoperative ventilator use			0.052
Yes	31 (55.4%)	91 (40.8%)
No	25 (44.6%)	132 (59.2%)
Days of ventilator^b	1 (1-1.5)	1 (1–2)	0.141
Length of hospital stay	8 (6-11.5)	8 (6–12)	0.766
Healthcare cost^c (Thai Baht)	223,605 (171,454 − 336,247.5)	216,326 (142,104–316,712.3)	0.905
Neurocognitive status
POD	8 (14.3%)	37 (16.6%)	0.839
POCD^d	23 (50%)	42 (24.3%)	0.001*
- Preoperative MoCA	26.54 ± 1.44	20.89 ± 1.89	< 0.001*
- Postoperative MoCA^d	23.85 ± 4.92	21.25 ± 3.64	0.001*
Patients with preceding POD^e	No (n = 186)	Yes (n = 33)
Subsequent POCD^e	44 (23.7%)	21 (63.6%)	< 0.001*

(a) Total n = 124: non-MCI = 31, MCI = 93. (b) Total n = 122: non-MCI = 31, MCI = 91. (c) Total n = 277: non-MCI = 56, MCI = 221. (d) Total n = 219: non-MCI = 46, MCI = 173. (e) Patients who had complete data on pre- and postoperative MoCA scores, Total n = 219: no preceding POD = 186, with preceding POD = 33.
ICU, intensive care unit; MCI, mild cognitive impairment; MoCA, Montreal Cognitive Assessment; POCD, postoperative cognitive dysfunction; POD, postoperative delirium
*Significance at P < 0.05

ISSN: 1471-2318