Early postoperative neurocognitive complications in elderly patients: comparing those with and without preexisting mild cognitive impairment– a prospective study

Table 3 Postoperative patient conditions

Variables	Non-MCI (n = 56)	MCI (n = 223)	P
Benzodiazepine use^a	11 (19.6%)	20 (9.0%)	0.032*
Opioid use^b	4 (7.1%)	9 (4.0%)	0.302
Tricyclic antidepressant use^c	3 (5.4%)	0 (0.0%)	0.008*
Antihistamine use^d	1 (1.8%)	3 (1.3%)	1.000
Poorly controlled pain	5 (8.9%)	10 (4.5%)	0.192
Anemia	7 (12.5%)	12 (5.4%)	0.074
Blood transfusion	7 (12.5%)	3 (1.3%)	0.001*
Hypotension	3 (5.4%)	7 (3.1%)	0.425
Cardiac arrest	1 (1.8%)	8 (3.6%)	0.692
Myocardial infarction	1 (1.8%)	2 (0.9%)	1.000
Arrhythmia	11 (19.6%)	50 (22.4%)	0.856
Coma	1 (1.8%)	8 (3.6%)	0.692
Cerebrovascular accident	0 (0.0%)	6 (2.7%)	0.602
Convulsion	0 (0.0%)	4 (1.8%)	0.587
Acute kidney injury	4 (7.1%)	28 (12.6%)	0.349
Urinary retention	1 (1.8%)	4 (1.8%)	1.000
Urinary tract infection	0 (0.0%)	10 (4.5%)	0.133
Oxygen desaturation	4 (7.1%)	18 (8.1%)	1.000
Pneumonia	0 (0.0%)	13(5.8%)	0.078
Pulmonary embolism	0 (0.0%)	2 (0.9%)	1.000
Re-operation	3 (5.4%)	10 (4.5%)	1.000
Death	0 (0.0%)	9 (4.0%)	0.212

(a) Lorazepam, clonazepam, diazepam, midazolam; (b) Tramadol, pethidine; (c) Amitriptyline, Nortriptyline; (d) First generation antihistamines: chlorpheniramine, hydroxyzine, diphenhydramine
MCI: mild cognitive impairment
*Significance at P < 0.05

ISSN: 1471-2318