Table 1 Summary of signs and symptoms from reported memantine overdose cases
From: Case report: a unique presentation of memantine overdose causing echolalia and hypertension
CASES | 1 2000 mg, acute | 2 400 mg, acute | 3 50 mg/day, > 12 months | 4 105–200 mg/day, 3 days | 5 Unknown doses |
|---|---|---|---|---|---|
REPORTED SIGNS AND SYMPTOMS | Comatose Nystagmus, mydriasis, diplopia Disorientation Tachycardia, hypertension | Agitation Visual hallucinations Psychosis Somnolence, unconsciousness Proconvulsive state | Dyspepsia | Tiredness, weakness Diarrhea No symptoms | CNS (confusion, drowsiness, somnolence, vertigo, agitation, aggression, hallucination, and gait disturbance) Gastrointestinal (vomiting and diarrhea) |