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Table 2 Association between SII with MetS and its components

From: Association of systemic immunity-inflammation index with metabolic syndrome in U.S. adult: a cross-sectional study

 

Crude model

Model I

Model II

OR (95% CI) P

OR (95% CI) P

OR (95% CI) P

MetS

 Log2-SII

1.33 (1.22, 1.45) < 0.0001

1.32 (1.20, 1.45) < 0.0001

1.18 (1.07, 1.30) 0.0059

 SII quartiles

  Q1

Ref

Ref

Ref

  Q2

1.12 (0.96, 1.30) 0.1499

1.15 (0.99, 1.34) 0.0815

0.99 (0.83, 1.19) 0.9430

  Q3

1.38 (1.13, 1.69) 0.0039

1.40 (1.12, 1.75) 0.0064

1.08 (0.86, 1.34) 0.5195

  Q4

1.75 (1.46, 2.09) < 0.0001

1.77 (1.46, 2.14) < 0.0001

1.36 (1.10, 1.70) 0.0214

 P for trend

 < 0.0001

 < 0.0001

0.011

Hypertension

 Log2-SII

1.22 (1.12, 1.34) 0.0001

1.24 (1.13, 1.36) 0.0001

1.22 (1.12, 1.34) 0.0010

 SII quartiles

  Q1

Ref

Ref

Ref

  Q2

1.01 (0.84, 1.21) 0.9192

1.06 (0.82, 1.36) 0.6647

1.06 (0.80, 1.42) 0.6824

  Q3

1.06 (0.88, 1.27) 0.5374

1.04 (0.83, 1.32) 0.7264

0.98 (0.79, 1.22) 0.8698

  Q4

1.50 (1.27, 1.78) 0.0001

1.59 (1.28, 1.96) 0.0002

1.53 (1.22, 1.92) 0.0054

 P for trend

 < 0.0001

 < 0.0001

0.002

Hyperglycemia

 Log2-SII

1.11 (1.02, 1.21) 0.0253

1.13 (1.04, 1.23) 0.0078

1.08 (1.00, 1.17) 0.0885

 SII quartiles

  Q1

Ref

Ref

Ref

  Q2

1.06 (0.87, 1.29) 0.5669

1.09 (0.89, 1.34) 0.3944

1.04 (0.84, 1.30) 0.7249

  Q3

1.05 (0.84, 1.30) 0.6886

1.08 (0.86, 1.36) 0.5003

0.98 (0.76, 1.25) 0.8497

  Q4

1.23 (1.03, 1.47) 0.0343

1.28 (1.08, 1.51) 0.0095

1.15 (0.96, 1.38) 0.1644

 P for trend

0.054

0.023

0.259

Low HDL

 Log2-SII

1.29 (1.14, 1.46) 0.0003

1.27 (1.12, 1.43) 0.0007

1.11 (0.96, 1.28) 0.1706

 SII quartiles

  Q1

Ref

Ref

Ref

  Q2

1.07 (0.85, 1.35) 0.5499

1.06 (0.85, 1.33) 0.6047

0.93 (0.72, 1.20) 0.5896

  Q3

1.51 (1.15, 1.99) 0.0062

1.46 (1.12, 1.92) 0.0104

1.18 (0.88, 1.59) 0.3058

  Q4

1.63 (1.27, 2.08) 0.0006

1.57 (1.23, 2.00) 0.0014

1.18 (0.89, 1.56) 0.2784

 P for trend

 < 0.001

 < 0.001

0.136

Hypertriglyceridemia

 Log2-SII

1.15 (1.06, 1.25) 0.0020

1.19 (1.09, 1.30) 0.0007

1.06 (0.95, 1.17) 0.3185

 SII quartiles

  Q1

Ref

Ref

Ref

  Q2

1.21 (1.00, 1.46) 0.0576

1.24 (1.02, 1.50) 0.0388

1.09 (0.89, 1.33) 0.4321

  Q3

1.41 (1.13, 1.76) 0.0056

1.50 (1.18, 1.89) 0.0027

1.23 (0.96, 1.58) 0.1337

  Q4

1.31 (1.10, 1.57) 0.0063

1.40 (1.16, 1.69) 0.0020

1.09 (0.88, 1.35) 0.4593

 P for trend

0.005

0.002

0.372

Central obesity

 Log2-SII

1.41 (1.26, 1.58) < 0.0001

1.33 (1.19, 1.50) < 0.0001

1.12 (0.94, 1.34) 0.2177

 SII quartiles

  Q1

Ref

Ref

Ref

  Q2

1.34 (1.08, 1.67) 0.0147

1.39 (1.10, 1.75) 0.0118

1.21 (0.83, 1.76) 0.3433

  Q3

1.69 (1.36, 2.10) 0.0001

1.60 (1.26, 2.01) 0.0006

1.03 (0.72, 1.47) 0.8920

  Q4

2.03 (1.57, 2.62) < 0.0001

1.86 (1.44, 2.40) 0.0001

1.28 (0.87, 1.89) 0.2360

 P for trend

 < 0.0001

 < 0.0001

0.335

  1. Abbreviations: Ref Reference, OR odds ratio, CI confidence interval
  2. Crude model: non-adjusted (univariate analysis); Model I: age and sex were adjusted; Model II: Model I plus BMI, Race, education, PIR, minutes sedentary activity, smoking behavior, drinking status, recreational. activity, minutes sedentary activity, BUN, SUA, and CR were adjusted