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Table 2 Association between known prognostic factors and age categories according to the Kruskal-Wallis test

From: Rhabdomyolysis in older adults: outcomes and prognostic factors

 

< 50 years

n = 64

50–59 years

n = 43

60–69 years

n = 43

70–79 years

n = 48

80–89 years

n = 105

> 90 years

n = 40

P

N = 343

Charlson mean(SD)

0.3 (0.8)

1.8 (2.4)

1.9 (2.3)

1.5 (2.0)

1.3 (1.2)

1.3 (1.5)

< 0.001

Number of drugs mean(SD)

2.7 (3.3)

3.6 (3.0)

5.4 (3.3)

6.1 (4.0)

5.4 (3.0)

5.1 (3.0)

< 0.001

Drugs < 8 N(%)

37 (57.8)

19 (44.2)

9 (22.5)

11 (24.9)

13 (12.9)

7 (17.5)

< 0.001

qSOFA ≥ 2 N(%)

8 (12.7)

6 (14.3)

3 (7.0)

3 (6.3)

9 (8.6)

1 (3.3)

0.38

Prolonged immobilization N(%)

5 (7.9)

17 (39.5)

22 (51.2)

43 (89.6)

98 (93.3)

39 (97.5)

< 0.001

Initial CK (median)

3,150 (1,331 − 13,902)

4,507 (1,952 − 10,502)

3,959 (1,560–7,691)

3,528 (1,495–6,128)

1,830 (1,316–4,405)

1,931 (1,280–3,636)

< 0.001

CK peak (median)

5,988 (2,579 − 21,783)

4,754 (1,925 − 12,430)

4,072 (1,990 − 17,595)

4,122 (1,805–8,661)

1,900 (1,340–4,601)

1,993 (1,326–3,636)

< 0.001

CK ≥ 5,000 UI/L N(%)

34 (54.0)

21 (48.8)

16 (37.2)

19 (39.6)

25 (23.8)

5 (12.5)

< 0.001

Peak creatinine

(median)

105 (73–200)

91 (68–217)

124 (88–177)

83.5 (70–111)

84 (61–125)

86.5 (69.5–110)

0.01

Phosphorus (median)

1.1 (0.9–1.4)

1.0 (0.8–1.4)

1.1 (0.8–1.4)

0.9 (0.8–1.1)

0.9 (0.8–1.1)

1.1 (0.9–1.4)

0.20

Bicarbonates

(median)

24 (18–26)

23 (19–25)

22.5 (20–25)

22 (19–24)

23 (20–25)

23.5 (21–27)

0.62

Acute Renal Failure N(%)

35 (56.5)

26 (61.9)

29 (67.4)

19 (52.9)

40 (50.6)

16 (59.3)

0.55

Dissaminated Intravascular coagulation N

1

3

1

0

0

0

0.09

Delirium N(%)

13 (21)

12 (28.6)

6 (14.3)

9 (25.7)

28 (34.6)

8 (27.6)

0.23

IV infusion > 2 L N(%)

27 (43.6)

13 (33.3)

12 (29.3)

11 (23.9)

14 (13.9)

1(2.6)

< 0.001

Returned home N(%)

48 (76.2)

21 (48.8)

24 (55.8)

15 (31.3)

34 (32.4)

11 (27.5)

< 0.001

30-day hospital mortality N(SD)

1 (1.7)

2 (4.9)

7 (17.1)

4 (8.9)

8 (8.9)

3 (10)

0.14

  1. qSOFA stands for quick Sequential Organ Failure Assessment [15]
  2. SD stands for Standart Deviation
  3. N stands for Number
  4. % stands Percentages, calculated taking into account missing data