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Table 3 Incidence of MACE per 100 person-years in the TAH group and control group

From: Thiazide-associated hyponatremia increases the risk of major adverse cardiovascular events among elderly Taiwanese patients

 

TAH group

 

Control group

  

Event

No. of

events

Person-

years

Incidence rate

 

No. of

Event

Person-

years

Incidence rate

Crude HR*

(95%CI)

Adjusted HR**

(95%CI)

MACE

128

4001

3.20

 

254

13,025

1.95

1.56(1.26‒1.92)

1.29(1.01‒1.65)

All-cause death

316

5066

6.24

 

507

16,199

3.13

2.02(1.75‒2.32)

1.39(1.19‒1.63)

CV death

24

5066

0.47

 

36

16,199

0.22

2.01(1.20‒3.37)

1.61(0.90‒2.92)

Major coronary

65

4001

1.62

 

129

13,025

0.99

1.56(1.16‒2.11)

1.07(0.76‒1.50)

Stroke

63

4001

1.57

 

125

13,025

0.96

1.56(1.15‒2.11)

1.61(1.14‒2.27)

  1. *Incidence rate ratio: TAH group versus control group (95%CI).
  2. **Adjusted for age, CCIS, DM, ARB, CCB, α-blockers, β-blockers, and furosemide.