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Table 5 Determinants of DRPs identified using logistic regression

From: Drug-related problems in hospitalized patients with chronic kidney diseases and clinical pharmacist interventions

Determinates

Patients

with DRP

(total 420), N(%)

Patients without DRP

(total 494), N(%)

Univariable logistic regression analysis

Multivariate logistic regression analysis

Crude OR

(95%CI)

p value

Adjusted OR

(95%CI)

p value

Age (year), Mean(SD)

62.40 ± 17.37

58.36 ± 18.02

1.013 (1.006–1.021)

0.001*

1.001(0.993–1.010)

0.771

Gender

 Female

265

(63.10)

299

(60.52)

Reference

   

 Male

155

(36.90)

195

(39.47)

0.897 (0.686–1.173)

0.426

  

Smoking status

 No

331

(78.81)

403

(81.58)

Reference

   

 Yes

89

(21.19)

91

(18.42)

1.191

(0.859–1.650)

0.294

  

Alcohol user

 No

365

(86.90)

438

(88.66)

Reference

   

 Yes

55

(13.10)

56

(11.34)

1.179

(0.792–1.753)

0.417

  

Stage of CKD patients

 CKD 1

48

(11.43)

101

(20.45)

Reference

 

Reference

 

 CKD 2

32

(7.62)

52

(10.53)

1.295

(0.741–2.264)

0.365

0.977(0.542–1.761)

0.939

 CKD 3

23

(5.48)

33

(6.68)

1.467

(0.778–2.764)

0.236

1.132(0.583–2.198)

0.714

 CKD 4

23

(5.48)

13

(2.63)

3.723

(1.738–7.976)

0.001*

2.342(1.045–5.253)

0.039*

 CKD 5

294

(70)

295

(59.72)

2.097

(1.435–3.065)

0.000*

1.249(0.809–1.927)

0.315

Number of comorbidities, Mean (SD)

3.34 ± 1.45

2.93 ± 1.15

1.272

(1.148–1.410)

0.000*

1.187(1.059–1.329)

0.003*

Number of prescribed drugs during hospitalization, Mean(SD)

17.00 ± 9.20

12.86 ± 7.58

1.062

(1.044–1.080)

0.000*

1.050(1.031–1.069)

0.000*

Length of hospital stay (day), Mean(SD)

9.56 ± 4.46

8.08 ± 4.51

1.076 (1.044–1.108)

0.000*

1.035(1.001–1.071)

0.043*

  1. DRPs: drug-related problems; OR: odds ratio; CI: confidence interval;* indicates P < 0.05