Dementia subtypes, cognitive decline and survival among older adults attending a memory clinic in Cape Town, South Africa: a retrospective study

Table 8 Predictors of survival among patients with dementia—Multivariate cox regression analysis

	Std err	z	HR	95% CI	p-value
Age at onset
> 65 years	0.46	2.38	1.82	1.11—2.99	0.017
Gender
Female	0.14	-2.18	0.59	0.36—0.95	0.029
Marital Status
Married	0.26	-0.44	0.86	0.48—1.58	0.660
Single	0.99	1.44	2.02	0.78—5.26	0.149
Widowed	0.23	-1.16	0.67	0.34—1.32	0.246
Years of Education
8 to 12	0.40	1.65	1.54	0.92—2.57	0.098
≥ 13	0.42	0.24	1.10	0.51—2.33	0.813
Charlson's Weighted Comorbidity score
3 to 4	0.48	2.46	1.88	1.14—3.10	0.014
≥ 5	0.53	2.52	1.97	1.16—3.34	0.012
Baseline MMSE
Median (IQR)	0.02	2.18	1.05	1.01—1.10	0.029
Dementia subtype
VND	0.44	0.91	1.34	0.71—2.55	0.365
DLB/PDD	1.12	3.07	3.07	1.50—6.29	0.002
FTD	1.06	0.74	1.63	0.45—5.87	0.458
Mixed	1.28	0.74	1.73	0.41—7.36	0.457

Abbreviations: n number, IQR Inter Quartile Range, MMSE Mini-Mental State Examination, HR Hazard Ratio, CI confidence interval, VND Major Vascular Neurocognitive Disorder, DLB Dementia with Lewy bodies, PDD Parkinson’s disease dementia, FTD Fronto-temporal dementia

ISSN: 1471-2318