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Table 7 Univariate analysis of baseline characteristics and survival

From: Dementia subtypes, cognitive decline and survival among older adults attending a memory clinic in Cape Town, South Africa: a retrospective study

Characteristics

Alive

Dead

HR (95% CI)

p value

Age at onset (years)

 < 65 years

17 (32.1)

29 (26.1)

1

 

  > 65 years

36 (67.9)

82 (73.9)

1.41 (0.92—2.16)

0.117

Gender: n (%)

 Male

18 (34.0)

46 (41.1)

1

 

 Female

35 (66.0)

66 (58.9)

0.59 (0.40—0.86)

0.006

Marital Status: n (%)

 Divorced

4 (7.6)

16 (14.3)

1

 

 Married

35 (66.0)

56 (50.0)

0.86 (0.49—1.50)

0.596

 Single

0

7 (6.3)

2.05 (0.84—5.02)

0.115

 Widowed

14 (26.4)

33 (29.5)

0.72 (0.39—1.32)

0.291

Years of Education: n (%)

 0 to 7

13 (25.0)

26 (23.2)

1

 

 8 to 12

31 (59.6)

74 (66.1)

1.37 (0.86—2.17)

0.181

  > 12

8 (15.4)

12 (10.7)

1.16 (0.58—2.34)

0.671

Charlson's Weighted Comorbidity score

 1 to 2

27 (50.9)

39 (34.8)

1

 

 3 to 4

16 (30.2)

39 (34.8)

1.43 (0.91—2.24)

0.117

  ≥ 5

10 (18.9)

34 (30.4)

1.81 (1.13—2.89)

0.013

Baseline MMSE

 Median (IQR)

22 (5)

21 (6)

0.97 (0.94—1.01)

0.201

MAP

 Median (IQR)

99.3 (18.3)

101.7 (16.7)

1.01 (0.99—1.03)

0.512

 Mean (SD)

101.0 (14.0)

103.5 (14.5)

  

Dementia subtype

 AD

38 (77.6)

79 (71.8)

1

 

 VND

8 (16.3)

16 (14.6)

1.83 (1.06—3.18)

0.030

 DLB/PDD

1 (2.0)

10 (9.1)

3.55 (1.82—6.97)

 < 0.001

 FTD

0

2 (2.7)

1.77 (0.56—6.65)

0.334

 Mixed

2 (4.1)

2 (1.8)

1.01 (0.25—4.15)

0.986

  1. Abbreviations: n number, SD Standard Deviation, IQR Inter Quartile Range, MMSE Mini-Mental State Examination, MAP Mean Arterial Pressure, HR Hazard Ratio, CI confidence interval, AD Major Neurocognitive Disorder due to Alzheimer’s disease, VND Major Vascular Neurocognitive Disorder, DLB Dementia with Lewy bodies, PDD Parkinson’s disease dementia, FTD Fronto-temporal dementia