Study period | ||||||
---|---|---|---|---|---|---|
Time points | Enrolment | Baseline | Intervention | Post intervention | Follow –up | |
Week -1 | Week 0 | Week 1–26 | Week 26 + 2 | Week 52 + 2 | ||
Eligibility screening | x | |||||
Informed consent | x | |||||
Allocation | x | |||||
Intervention | x | |||||
Yoga | x | |||||
Waitlist | x | x | ||||
Assessments | ||||||
Demographics | Study Proforma | x | ||||
KDM predictors of biological age | Glycated hemoglobin, Forced expiratory volume in one second, Systolic Blood pressure, Total cholesterol, C-reactive protein, Creatinine, Urea nitrogen, Albumin, Alkaline phosphatase, fasting blood sugar, low density lipoprotein- Cholesterol and Cytomegalovirus IgG | x | x | x | ||
Aging marker | Telomere length | x | x | x | ||
Body Composition | Body mass index (BMI) | x | x | x | ||
Mechanistic markers | Inflammation [IL-6, hsCRP, TNF-RII] | x | x | x | ||
Insulin signaling [Insulin and IGF1] | x | x | x | |||
Renal function (cystatin) | x | x | x | |||
Senescence [GDF-15] | x | x | x | |||
Cardiovascular function [NT proBNP] | x | x | x | |||
Strength | Hand grip strength | x | x | x | ||
Locomotion | Gait speed | |||||
Balance | Berg balance scale | x | x | x | ||
Cognition | Digit symbol substitution task | x | x | x | ||
Functionality | Activities of daily living | x | x | x |