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Table 3 Medications used by COVID-19 patients with dementia and matched controls without dementia during hospitalisation

From: Clinical characteristics and outcomes of COVID-19 patients with preexisting dementia: a large multicenter propensity-matched Brazilian cohort study

Variables

Dementia

N = 4051

Control patientsa

N = 1,1511

p-value2

Anticoagulants

294 (72.6%)

882 (76.8%)

0.106

Antibiotics during acute phase of COVID-19

294 (72.6%)

872 (75.8%)

0.231

Antibiotics for nosocomial infection

277 (68.4%)

795 (69.2%)

0.814

Corticoids

276 (68.1%)

888 (77.3%)

 < 0.001

Vasoactive amines

90 (22.2%)

410 (35.6%)

 < 0.001

Oseltamivir

77 (32.1%)

231 (34.7%)

0.507

Nonsteroidal anti-inflammatory drugs

29 (18.8%)

53 (12.5%)

0.075

Inhaled corticoids

24 (14.5%)

78 (16.1%)

0.723

Statin

21 (13.6%)

61 (14.4%)

0.917

Antiarrhythmic

10 (6.5%)

47 (11.1%)

0.137

Antifungal

10 (3.1%)

46 (5.1%)

0.204

Hydroxychloroquine

9 (5.8%)

31 (7.3%)

0.663

Neuromuscular-blocking drug (except for intubation)

8 (4.8%)

54 (11.2%)

0.026

Clarithromycin

7 (4.5%)

22 (5.2%)

0.918

Convalescent plasma

2 (0.6%)

11 (1.2%)

0.533

Chloroquine

0 (0.0%)

 

0.122

Tocilizumab

0 (0.0%)

7 (0.8%)

0.200

Immunoglobulins

0 (0.0%)

4 (0.3%)

0.578

Interferon

0 (0.0%)

2 (0.5%)

 > 0.999

Remdesivir

0 (0.0%)

1 (0.1%)

 > 0.999

Favipiravir

0 (0.0%)

0 (0.0%)

 

Ritonavir/Lopinavir

0 (0.0%)

0 (0.0%)

 

Umifenovir

0 (0.0%)

0 (0.0%)

 

Other specific therapy instituted for COVID-19

21 (6.6%)

73 (8.0%)

0.475

No specific therapy instituted for COVID-19

86 (27.0%)

215 (23.7%)

0.269

  1. 1n (%); Median (IQR)
  2. 2Pearson's Chi-squared test; Wilcoxon rank sum test; Fisher's exact test
  3. aMatched controls (age, sex, comorbidities [arterial hypertension, diabetes mellitus, stroke, obesity, heart failure, and cancer], hospital, and year of admission)