Association between BMI trajectories in late-middle age and subsequent dementia risk in older age: a 26-year population-based cohort study

Table 2 The association between BMI trend and variation in late-middle age and risk of dementia in older age

Variables	Types	Model 1				Model 2				Model 3				Model 4
Variables	Types	No.participants	No.event	RR (95% CI)	P value	No.participants	No.event	ARR (95% CI)	P value	No.participants	No.event	ARR (95% CI)	P value	No.participants	No.event	ARR (95% CI)	P value
BMI trend	Ascend	6693	489	Reference	< 0.001	6672	486	Reference	0.002	6643	482	Reference	0.002	6643	482	Reference	0.001
BMI trend	Decline	4154	411	1.35 (1.19–1.54)		4141	409	1.23 (1.08–1.4)		4125	407	1.24 (1.08–1.42)		4125	407	1.27 (1.11–1.46)
BMI variation	Low	6622	490	Reference	< 0.001	6601	486	Reference	< 0.001	6576	481	Reference	< 0.001	6576	481	Reference	< 0.001
BMI variation	High	4225	410	1.31 (1.15–1.5)		4212	409	1.39 (1.22–1.6)		4192	408	1.37 (1.19–1.56)		4192	408	1.36 (1.19–1.56)

BMI Body mass index
Model 1 was a univariate model for the BMI trend
Model 2 was additionally adjusted for sex, education level, ethnicity, year of aged 65, and marital status
Model 3 was additionally adjusted for smoking status, alcohol consumption, and longstanding illness status
Model 4 was additionally adjusted for the mean BMI group

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