Variables | Hazard ratio | 95% CI HR | P-Value | |
---|---|---|---|---|
A univariate Cox proportional regression model | ||||
Age (Each year increase) | 1.02 | 0.99–1.05 | 0.124 | |
Sex (Male/Female) | 0.28 | 0.16–0.48 | < 0.001 | |
Body mass index (kg/m2) | Ideal body (18.5–25) | Reference group | ||
Low body (≤ 18.5) | 1.04 | 0.31–3.52 | 0.938 | |
Overweight (25-29.9) | 1.41 | 0.81–2.44 | 0.222 | |
Obesity (≥ 30) | 2.07 | 1.15–3.70 | 0.014 | |
Low grip strength (kg/cm2) (Female < 16) & (Male < 27) | 1.60 | 1.03–2.47 | 0.035 | |
Low gait speed (m/s), (≥ 0.8) | 3.91 | 1.58–9.68 | < 0.001 | |
calf circumference (Each centimeter increase) | 1.02 | 0.99–1.06 | 0.102 | |
Mid-arm circumference (Each centimeter increase) | 1.06 | 1.00–1.12 | 0.028 | |
Waist circumference (Each centimeter increase) | 1.02 | 1.00–1.04 | 0.010 | |
Urinary incontinence (Yes/No) | 1.35 | 0.73–2.49 | 0.339 | |
Cancer (Yes/No) | 2.06 | 0.65–6.54 | 0.219 | |
Hearing loss (Yes/No) | 1.23 | 0.63–2.39 | 0.531 | |
Visual impairment (Yes/No) | 1.19 | 0.73–1.92 | 0.468 | |
Diabetes mellitus (Yes/No) | 1.15 | 0.71–1.86 | 0.559 | |
Thyroid (Yes/No) | 1.36 | 0.59–3.14 | 0.463 | |
Chronic obstructive pulmonary disease (Yes/no) | 1.01 | 0.14–7.31 | 0.987 | |
Hypertension (Yes/No) | 1.02 | 0.65–1.59 | 0.915 | |
Congestive heart failure (Yes/No) | 1.31 | 0.69–2.49 | 0.395 | |
Cerebrovascular accident (Yes/No) | 1.63 | 0.71–3.75 | 0.248 | |
Acute Myocardial Infarction (Yes/No) | 0.86 | 0.31–2.36 | 0.778 | |
Pain (Yes/No) | 1.56 | 0.86–2.82 | 0.142 | |
Osteoporosis (Yes/No) | 1.77 | 0.99–3.15 | 0.053 | |
Osteoarthritis (Yes/No) | 1.93 | 1.20–3.13 | < 0.001 | |
Cognitive function (MMSE) | Normal cognitive | Reference group | ||
Mild cognitive | 1.06 | 0.64–1.77 | 0.798 | |
Dementia | 1.56 | 0.80–3.02 | 0.185 | |
Depression (PHQ-9 score) | Normal mood (0–5) | Reference group | ||
Mild depression (5–9) | 1.17 | 0.65–2.10 | 0.586 | |
Moderate depression (10–14) | 2.05 | 1.11–3.76 | 0.020 | |
Moderately-severe depression (15–19) | 4.46 | 2.24–8.90 | < 0.001 | |
Severe Depression (20–27) | 5.31 | 2.06–13.67 | < 0.001 | |
Sleep Quality | Very good | Reference group | ||
Relatively good | 1.10 | 0.44–2.77 | 0.831 | |
Relatively poor | 1.37 | 0.51–3.68 | 0.526 | |
Very poor | 4.08 | 1.24–13.41 | 0.020 | |
Physical activity (Active/ Totally inactive) | 0.44 | 0.27–0.70 | < 0.001 | |
Impair balance (TUG), (> 12 s) | 2.29 | 1.47–3.577 | < 0.001 | |
SPPB (Each score increase) | 0.57 | 0.40–0.80 | < 0.001 | |
Smoking (Yes/No) | 0.41 | 0.13–1.32 | 0.139 | |
Polypharmacy (Yes/No) | 1.73 | 1.03–2.91 | 0.036 | |
Nutrition status (MNA) | Well nutrition (≥ 24) | Reference group | ||
At risk of malnutrition (17–24) | 1.79 | 1.13–2.81 | 0.011 | |
Malnutrition (≤ 17) | 2.82 | 0.68–11.61 | 0.151 | |
ADL (Barthel’s index), (Independent/Dependent) | 0.57 | 0.36 − 0.89 | 0.013 | |
IADL (Lawton IADL), (Independent/Dependent) | 0.86 | 0.78–0.95 | < 0.001 | |
Marital status (Married/ No married) | 0.54 | 0.33–0.88 | 0.014 | |
Job status | Retire | Reference group | ||
Employed | 0.29 | 0.06–1.24 | 0.096 | |
Housekeeper | 2.09 | 1.27–3.44 | < 0.001 | |
Unemployed | 1.06 | 0.31–3.55 | 0.922 | |
Education years (Each year increase) | 0.97 | 0.93–1.02 | 0.290 | |
Living arrangement (Live alone/ live with) | 1.18 | 0.62–2.23 | 0.603 | |
Wealth Index quintile | First (Poorest) | Reference group | ||
Second | 0.85 | 0.43–1.68 | 0.656 | |
Third | 0.97 | 0.50–1.86 | 0.928 | |
Fourth | 0.48 | 0.22–1.06 | 0.071 | |
Fifth (Richest) | 0.94 | 0.49–1.82 | 0.872 | |
Multiple Cox proportional regression model | ||||
Sex (Male/Female) | 0.37 | 0.21–0.64 | < 0.001 | |
Depression (PHQ-9 score) | Normal mood (0–5) | Reference group | ||
Mild depression (5–9) | 0.81 | 0.44–1.47 | 0.492 | |
Moderate depression (10–14) | 1.31 | 0.70–2.45 | 0.382 | |
Moderately-severe depression (15–19) | 2.97 | 1.47–6.01 | < 0.001 | |
Severe Depression (20–27) | 3.26 | 1.24–8.54 | 0.016 | |
Physical activity (Active/ Totally inactive) | 0.59 | 0.36–0.96 | 0.034 | |
Impair balance (TUG), (> 12 s) | 1.73 | 1.10–2.72 | 0.017 |