Age, years | ≥ 50 | 50–59 | 60–69 | 70–79 | > 80 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Group | Female | Male | P value | Female | Male | P value | Female | Male | P value | Female | Male | P value | Female | Male | P value |
Cases, n | 20,983 | 10,282 | Â N/A | 3,839 | 3,495 | Â N/A | 5,977 | 2,644 | Â N/A | 5,623 | 1,963 | Â N/A | 5,544 | 2,180 | Â N/A |
Any anti-OP drug, n (%) | 11,094 (52.87) | 4,200 (40.85) | < 0.0001 | 1,732 (45.12) | 1,099 (31.44) | < 0.0001 | 3,354 (56.12) | 1,091 (41.26) | < 0.0001 | 3,222 (57.30) | 940 (47.89) | < 0.0001 | 2,786 (50.25) | 1,071 (49.13) | 0.3738 |
Ca and/or ordinary VD, n (%) | 3,259 (15.53) | 1,503 (14.62) | 0.0346 | 609 (15.86) | 506 (14.48) | 0.0988 | 935 (15.64) | 381 (14.41) | 0.1420 | 903 (16.06) | 281 (14.31) | 0.0668 | 797 (14.38) | 305 (14.00) | 0.6632 |
Active VD, n (%) | 5,360 (25.54) | 1,600 (15.56) | < 0.0001 | 779 (20.29) | 327 (9.36) | < 0.0001 | 1,761 (29.46) | 419 (15.85) | < 0.0001 | 1,636 (29.09) | 397 (20.22) | < 0.0001 | 1,184 (21.36) | 457 (20.96) | 0.7038 |
Calcitonin, n (%) | 6,276 (29.91) | 2,241 (21.80) | < 0.0001 | 873 (22.74) | 432 (12.36) | < 0.0001 | 1,866 (31.22) | 581 (21.97) | < 0.0001 | 1,856 (33.01) | 548 (27.92) | 0.0007 | 1,681 (30.32) | 641 (29.40) | 0.4287 |
Bisphosphonates, n (%) | 1,831 (8.73) | 474 (4.61) | < 0.0001 | 273 (7.11) | 69 (1.97) | < 0.0001 | 657 (10.99) | 145 (5.48) | < 0.0001 | 521 (9.27) | 135 (6.88) | 0.0012 | 380 (6.85) | 119 (5.46) | 0.0247 |
Denosumab, n (%) | 152 (0.72) | 37 (0.36) | < 0.0001 | 16 (0.42) | 11 (0.31) | 0.4711 | 58 (0.97) | 10 (0.38) | 0.0042 | 48 (0.85) | 8 (0.41) | 0.0468 | 30 (0.54) | 8 (0.37) | 0.3248 |
Chinese medicine, n (%) | 116 (1.13) | 240 (1.14) | 0.9028 | 78 (2.03) | 74 (2.12) | 0.7973 | 65 (1.09) | 23 (0.87) | 0.3540 | 47 (0.84) | 11 (0.56) | 0.2277 | 50 (0.90) | 8 (0.37) | 0.0142 |