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Table 1 The Baseline clinical characteristics of MIMIC-IV and eICU-CRD patients

From: Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study

Categories

MIMIV-IV

eICU-CRD

Overall

Non-delirium

Delirium

P value

Overall

Non-delirium

Delirium

P value

Total

4,649

2,484

2,165

 

1,844

1,289

555

 

Demographic

        

Age, years,

76 (70,83)

76 (70,83)

76 (70,83)

0.911

75 (70,82)

75 (69,81)

76 (70,82)

0.036

Sex, n(%)

   

0.812

   

0.999

Male

2,506 (53.9)

1,343 (54.1)

1,163 (53.7)

 

937 (50.8)

655 (50.8)

282 (50.8)

 

Female

2,143 (46.1)

1,141 (45.9)

1,002 (46.3)

 

907 (49.2)

634 (49.2)

273 (49.2)

 

Ethnicity, n(%)

   

< 0.001

   

0.265

White

3,168 (68.1)

1,795 (72.3)

1,373 (63.4)

 

1,394 (75.6)

965 (74.9)

429 (77.3)

 

Other

1,481 (31.9)

689 (27.7)

792 (36.6)

 

450 (24.4)

324 (25.1)

126 (22.7)

 

Vital signs

        

Temperature, °C

36.7 (36.4,37.0)

36.7 (36.4,37)

36.8 (36.5,37.1)

< 0.001

36.4 (36.2,36.7)

36.4 (36.2,36.7)

36.4 (36.1,36.7)

0.821

Heart rate, beats/minute

85 (73,100)

84 (72,98)

86 (74,102)

< 0.001

84 (70,100)

82 (69,98)

86 (74,102.5)

< 0.001

Mean blood pressure, mmHg

84 (72,97)

83 (71,96)

86 (74,99)

< 0.001

67 (53,131)

66 (53,128)

72 (51,137)

0.186

Respiratory rate, beats/minute

19 (16,23)

18 (16,23)

20 (16,24)

< 0.001

19 (16,23)

19 (16,23)

19 (16,23)

0.72

Laboratory tests

        

Albumin, g/dL

3.4 (2.8,3.9)

3.5 (2.9,3.9)

3.3 (2.8,3.8)

< 0.001

3 (2.5,3.4)

3 (2.6,3.4)

2.9 (2.4,3.3)

< 0.001

BUN, mg/dL

22 (16,36)

21 (16,34)

23 (16,37)

< 0.001

21 (15,33)

21 (15,31)

23 (15,37)

0.005

Creatinine, mg/dL

1.1 (0.8,1.5)

1 (0.8,1.5)

1.1 (0.8,1.6)

0.037

1.1 (0.8,1.6)

1 (0.8,1.5)

1.1 (0.8,1.7)

0.027

Serum sodium, mEq/L

139 (136,141)

139 (136,141)

139 (136,142)

0.206

139 (136,141)

139 (136,141)

139 (136,142)

0.01

Serum potassium, mEq/L

4.1 (3.8,4.6)

4.2 (3.8,4.5)

4.1 (3.8,4.6)

0.677

4.1 (3.7,4.5)

4.1 (3.7,4.5)

4 (3.7,4.6)

0.564

INR

1.2 (1.1,1.5)

1.2 (1.1,1.5)

1.2 (1.1,1.5)

0.116

1.1 (1,1.3)

1.1 (1,1.3)

1.2 (1.1,1.4)

< 0.001

WBC, 109/L

10.6 (7.7,14.7)

10.5 (7.7,14.4)

10.8 (7.7,15.1)

0.057

10.3 (7.7,14.3)

10 (7.4,13.8)

11.6 (8.4,16)

< 0.001

RBC, 109/L

3.7 (3.1,4.2)

3.6 (3.1,4.2)

3.7 (3.1,4.3)

0.358

3.8 (0.7)

3.9 (0.7)

3.8 (0.8)

0.007

Platelet, 109/L

204 (150,267)

205 (152,269.2)

201 (150,265)

0.119

197 (152,250)

199 (153,246)

194 (149,260.5)

0.933

Triglycerides, mg/dL

109 (79,156)

106 (77,149)

113 (81,165)

< 0.001

102 (76,145)

101 (76,142)

105 (75.5,157)

0.145

Glucose, mg/dL

132 (106,171)

129.5 (105,167)

135 (108,176)

< 0.001

128 (106,168)

126 (103,165)

135 (112,176)

< 0.001

TyG index

8.9 (8.5,9.4)

8.9 (8.4,9.3)

9 (8.5,9.5)

< 0.001

8.9 (8.4,9.3)

8.8 (8.4,9.2)

8.9 (8.5,9.4)

0.003

Comorbidities

        

Myocardial infarction, n(%)

   

< 0.001

   

< 0.001

No

3,390 (72.9)

1,716 (69.1)

1,674 (77.3)

 

1,261 (68.4)

832 (64.5)

429 (77.3)

 

Yes

1,259 (27.1)

768 (30.9)

491 (22.7)

 

583 (31.6)

457 (35.5)

126 (22.7)

 

Cerebrovascular disease, n(%)

   

< 0.001

   

< 0.001

No

2,770 (59.6)

1,651 (66.5)

1,119 (51.7)

 

1,253 (68)

925 (71.8)

328 (59.1)

 

Yes

1,879 (40.4)

833 (33.5)

1,046 (48.3)

 

591 (32)

364 (28.2)

227 (40.9)

 

Chronic pulmonary disease, n(%)

   

0.363

   

0.945

No

3,356 (72.2)

1,807 (72.7)

1,549 (71.5)

 

1,477 (80.1)

1,033 (80.1)

444 (80)

 

Yes

1,293 (27.8)

677 (27.3)

616 (28.5)

 

367 (19.9)

256 (19.9)

111 (20)

 

Diabetes, n(%)

   

0.025

   

0.343

No

3,058 (65.8)

1,670 (67.2)

1,388 (64.1)

 

1,267 (68.7)

877 (68)

390 (70.3)

 

Yes

1,591 (34.2)

814 (32.8)

777 (35.9)

 

577 (31.3)

412 (32)

165 (29.7)

 

Renal disease, n(%)

   

0.02

   

0.887

No

3,446 (74.1)

1,876 (75.5)

1,570 (72.5)

 

1,555 (84.3)

1,088 (84.4)

467 (84.1)

 

Yes

1,203 (25.9)

608 (24.5)

595 (27.5)

 

289 (15.7)

201 (15.6)

88 (15.9)

 

Malignant cancer, n(%)

   

0.614

   

0.264

No

3,966 (85.3)

2,113 (85.1)

1,853 (85.6)

 

1,493 (81)

1,035 (80.3)

458 (82.5)

 

Yes

683 (14.7)

371 (14.9)

312 (14.4)

 

351 (19)

254 (19.7)

97 (17.5)

 

Liver disease, n(%)

   

< 0.001

   

0.432

No

4,200 (90.3)

2,289 (92.1)

1,911 (88.3)

 

1,818 (98.6)

1,269 (98.4)

549 (98.9)

 

Yes

499 (9.7)

195 (7.9)

254 (11.7)

 

26 (1.4)

20 (1.6)

6 (1.1)

 

Hypertension, n(%)

   

0.018

   

0.761

No

2,310 (49.7)

1,194 (48.1)

1,116 (51.5)

 

544 (29.5)

383 (29.7)

161 (29)

 

Yes

2,339 (50.3)

1,290 (51.9)

1,049 (48.5)

 

1,300 (70.5)

906 (70.3)

394 (71)

 

Congestive heart failure, n(%)

   

0.266

   

0.663

No

2,978 (64.1)

1,573 (63.3)

1,405 (64.9)

 

1,420 (77)

989 (76.7)

431 (77.7)

 

Yes

1,671 (35.9)

911 (36.7)

760 (35.1)

 

424 (23)

300 (23.3)

124 (22.3)

 

Sepsis, n(%)

   

< 0.001

   

< 0.001

No

3,639 (78.3)

2,090 (84.1)

1,549 (71.5)

 

1,646 (89.3)

1,181 (91.6)

465 (83.8)

 

Yes

1,010 (21.7)

394 (15.9)

616 (28.5)

 

198 (10.7)

108 (8.4)

90 (16.2)

 

Events

        

RRT treatment, n(%)

   

< 0.001

   

0.013

No

4,210 (90.6)

2,326 (93.6)

1,884 (87)

 

1,764 (95.7)

1,243 (96.4)

521 (93.9)

 

Yes

439 (9.4)

158 (6.4)

281 (13)

 

80 (4.3)

46 (3.6)

34 (6.1)

 

MV, n(%)

   

< 0.001

   

< 0.001

No

2,412 (51.9)

1,594 (64.2)

818 (37.8)

 

984 (53.4)

758 (58.8)

226 (40.7)

 

Yes

2,237 (48.1)

890 (35.8)

1,347 (62.2)

 

860 (46.6)

531 (41.2)

329 (59.3)

 

ICU death, n(%)

   

< 0.001

   

< 0.001

Survivor

4,138 (89.0)

2,322 (93.5)

1,816 (83.9)

 

1,747 (94.7)

1,247 (96.7)

500 (90.1)

 

Non-survivor

511 (11.0)

162 (6.5)

349 (16.1)

 

97 (5.3)

42 (3.3)

55 (9.9)

 
  1. Abbreviations: MIMIC-IV, Medical Information Mart for Intensive Care IV; eICU-CRD, eICU Collaborative Research Database; RRT, Renal replacement therapy; MV, Mechanical ventilation; TyG, Triglyceride-glucose; ICU, Intensive care unit.
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