Fig. 1

Global cognitive decline by level of neuroticism and physical activity. This plot characterizes global cognitive decline over time in years as determined by mixed effects regression models. Each line in the plot represents one of four groups of participants: a) high physical activity and low neuroticism = black, dashed line; b) high physical activity and high neuroticism = red, dashed line; c) little physical activity and low neuroticism = black, solid line; and d) high physical activity and high neuroticism = red, dashed line