Table 3 Comparison of the risk for ACS between older patients with and without CP using competing risk survival analysis
Variable | Older patients with CP | Older patients without CP | Crude sHR (95% CI) | Adjusted sHR (95% CI)* | ||
|---|---|---|---|---|---|---|
Mortality (%) | ACS (%) | Mortality (%) | ACS (%) | |||
Overall analysis | 9061 (52.6) | 1021 (5.9) | 7782 (45.1) | 776 (4.5) | 1.33 (1.21 − 1.46) | 1.18 (1.07 − 1.30) |
Stratified analysis | ||||||
Age subgroups | ||||||
65–74 years | 4169 (41.3) | 558 (5.5) | 3299 (32.7) | 390 (3.9) | 1.45 (1.27 − 1.65) | 1.21 (1.06 − 1.39) |
75–84 years | 4215 (66.3) | 426 (6.7) | 3853 (60.6) | 351 (5.5) | 1.22 (1.06 − 1.41) | 1.13 (0.97 − 1.31) |
≥85 years | 677 (86.2) | 37 (4.7) | 630 (80.3) | 35 (4.5) | 1.07 (0.67 − 1.69) | 1.06 (0.66 − 1.70) |
Sex | ||||||
Male | 4478 (58.2) | 517 (6.7) | 4012 (52.2) | 407 (5.3) | 1.28 (1.13 − 1.46) | 1.15 (1.00 − 1.32) |
Female | 4583 (48.0) | 504 (5.3) | 3770 (39.5) | 369 (3.9) | 1.38 (1.21 − 1.58) | 1.21 (1.05 − 1.39) |
Underlying comorbidity | ||||||
Hypertension | 5087 (52.8) | 677 (7.0) | 3182 (48.8) | 383 (5.9) | 1.20 (1.06 − 1.36) | 1.18 (1.04 − 1.34) |
Diabetes | 2253 (59.8) | 317 (8.4) | 1490 (56.9) | 197 (7.5) | 1.12 (0.94 − 1.34) | 1.10 (0.92 − 1.31) |
Hyperlipidemia | 937 (42.9) | 155 (7.1) | 578 (39.2) | 94 (6.4) | 1.11 (0.86 − 1.44) | 1.08 (0.83 − 1.40) |
Coronary artery disease | 1898 (55.6) | 270 (7.9) | 1157 (51.5) | 156 (6.9) | 1.14 (0.94 − 1.39) | 1.13 (0.93 − 1.38) |
Malignancy | 741 (73.2) | 34 (3.4) | 392 (61.8) | 20 (3.2) | 1.07 (0.62 − 1.85) | 1.04 (0.58 − 1.86) |
Stroke | 1737 (63.2) | 192 (7.0) | 966 (65.1) | 102 (6.9) | 1.02 (0.81 − 1.30) | 1.01 (0.79 − 1.28) |
Dementia | 316 (77.6) | 23 (5.7) | 212 (81.2) | 9 (3.5) | 1.66 (0.77 − 3.59) | 1.75 (0.79 − 3.89) |
Congestive heart failure | 1653 (68.7) | 192 (8.0) | 1063 (69.4) | 120 (7.8) | 1.02 (0.81 − 1.28) | 1.03 (0.81 − 1.29) |
Chronic obstructive pulmonary disease | 2050 (61.9) | 231 (7.0) | 1150 (61.1) | 95 (5.1) | 1.39 (1.10 − 1.77) | 1.32 (1.04 − 1.68) |
Liver diseases | 960 (58.8) | 67 (4.1) | 588 (55.7) | 40 (3.8) | 1.08 (0.83 − 1.60) | 0.99 (0.66 − 1.47) |
Renal diseases | 944 (65.6) | 117 (8.1) | 581 (65.2) | 70 (7.9) | 1.04 (0.77 − 1.40) | 0.99 (0.73 − 1.34) |
Connective tissue disease | 210 (51.5) | 17 (4.2) | 72 (40.0) | 5 (2.8) | 1.50 (0.56 − 4.08) | 1.22 (0.46 − 3.22) |
Mental disorder | 4005 (53.7) | 414 (5.6) | 2432 (49.3) | 237 (4.8) | 1.16 (0.99 − 1.36) | 1.09 (0.93 − 1.28) |
Follow-up period | ||||||
< 1 year | 61 (0.4) | 19 (0.1) | 55 (0.3) | 11 (0.1) | 1.73 (0.82 − 3.63) | 1.55 (0.74 − 3.27) |
< 2 years | 140 (0.8) | 30 (0.2) | 132 (0.8) | 17 (0.1) | 1.77 (0.97 − 3.20) | 1.75 (0.96 − 3.18) |
< 3 years | 233 (1.4) | 46 (0.3) | 171 (1.0) | 23 (0.1) | 2.00 (1.21 − 3.30) | 1.80 (1.07 − 3.01) |