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Table 4 Logistic regression and hurdle regression results for risk factors for psychoactive polypharmacy in older men and women with dementia

From: An investigation of psychoactive polypharmacy and related gender-differences in older adults with dementia: a retrospective cohort study

Variable

Overall

OR (95% CI)

Men

OR (95% CI)

Women

OR (95% CI)

Logistic Regression

Age at diagnosis

0.97 (0.96, 0.97)*

0.96 (0.95, 0.97)*

0.97 (0.96, 0.98)*

Year of diagnosis 2005

Referent

Year of diagnosis 2006

1.08 (0.90, 1.30)

1.29 (0.90, 1.83)

1.00 (0.80, 1.25)

Year of diagnosis 2007

1.18 (0.99, 1.30)

0.87 (0.61, 1.25)

1.31 (1.06, 1.61)

Year of diagnosis 2008

0.96 (0.81, 1.14)

0.89 (0.64, 1.24)

1.16 (0.95, 1.42)

Year of diagnosis 2009

0.87 (0.74, 1.03)

0.84 (0.61, 1.16)

1.01 (0.83, 1.23)

Year of diagnosis 2010

0.71 (0.60, 0.84)*

0.80 (0.59, 1.09)

0.90 (0.74, 1.09)

Year of diagnosis 2011

0.71 (0.60, 0.84)*

0.69 (0.50, 0.95)*

0.71 (0.57, 0.87)*

Year of diagnosis 2012

0.62 (0.52, 0.74)*

0.41 (0.29, 0.58)*

0.74 (0.60, 0.91)*

Year of diagnosis 2013

0.55 (0.46, 0.66)*

0.50 (0.35, 0.70)*

0.57 (0.46, 0.72)*

Year of diagnosis 2014

0.39 (0.32, 0.48)*

0.45 (0.32, 0.64)*

0.34 (0.26, 0.45)*

Year of diagnosis 2015

0.29 (0.19, 0.44)*

0.17 (0.06, 0.36)*

0.37 (0.22, 0.58)*

Urban

0.95 (0.87, 1.03)

0.86 (0.74, 0.99)*

0.99 (0.89, 1.09)

Hurdle Regression

Age at diagnosis

0.98 (0.98, 0.99)*

0.98(0.97, 0.99)*

0.98 (0.97, 0.99)*

Year of diagnosis 2005

Referent

  

Year of diagnosis 2006

0.98 (0.77, 1.23)

1.15 (0.76, 1.76)

0.94 (0.71, 1.24)

Year of diagnosis 2007

0.95 (0.76, 1.20)

1.33 (0.87, 2.08)

0.86 (0.66, 1.12)

Year of diagnosis 2008

0.99 (0.79, 1.24)

1.04 (0.69, 1.57)

0.99 (0.76, 1.29)

Year of diagnosis 2009

0.97 (0.78, 1.20)

1.15 (0.77, 1.71)

0.92 (0.71, 1.19)

Year of diagnosis 2010

0.91 (0.74, 1.12)

1.25 (0.86, 1.83)

0.80 (0.62, 1.04)

Year of diagnosis 2011

0.88 (0.70, 1.10)

1.13 (0.76, 1.68)

0.81 (0.62, 1.07)

Year of diagnosis 2012

0.70 (0.55, 0.89)*

0.95 (0.60, 1.48)

0.64 (0.48, 0.85)*

Year of diagnosis 2013

0.61 (0.48, 0.79)*

0.72 (0.47, 1.12)

0.59 (0.43, 0.80)*

Year of diagnosis 2014

0.55 (0.41, 0.73)*

0.83 (0.52, 1.32)

0.43 (0.30, 0.64)*

Year of diagnosis 2015

0.57 (0.31, 1.04)

0.67 (0.20, 2.30)

0.54 (0.27, 1.07)

Urban

1.10 (0.98, 1.22)

1.22 (1.01, 1.48)*

1.05 (0.91, 1.20)

  1. * Signifies a statistically significant result