Table 2 Prognostic factors for OS in elderly patients without PMRT by univariable and multivariable analysis
Characteristics | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
Hazard ratio | 95%CI | P value | Hazard ratio | 95%CI | P value | |
Age group at diagnosis, y | 0.000 | 0.000 | ||||
70–74 | Reference | Reference | ||||
75–79 | 1.535 | 1.440–1.637 | 0.000 | 1.449 | 1.359–1.546 | 0.000 |
80–84 | 2.440 | 2.291-2.600 | 0.000 | 2.133 | 1.998–2.277 | 0.000 |
≥85 | 4.241 | 3.975–4.525 | 0.000 | 3.162 | 2.949–3.390 | 0.000 |
Race | 0.000 | 0.000 | ||||
White | Reference | Reference | ||||
Black | 1.199 | 1.113–1.290 | 0.000 | 1.360 | 1.236–1.497 | 0.000 |
Others | 0.656 | 0.596–0.721 | 0.000 | 1.510 | 1.344–1.697 | 0.000 |
Marital Status | 0.000 | 0.000 | ||||
Married | Reference | Reference | ||||
Unmarried | 1.708 | 1.629–1.791 | 0.000 | 1.270 | 1.209–1.334 | 0.000 |
Laterality | 0.512 | |||||
Left | Reference | |||||
Right | 0.986 | 0.944–1.029 | 0.512 | |||
Grade | 0.000 | 0.000 | ||||
Grade I | Reference | Reference | ||||
Grade II | 1.325 | 1.240–1.417 | 0.000 | 1.101 | 1.029–1.178 | 0.005 |
Grade III + IV | 1.899 | 1.776–2.030 | 0.000 | 1.337 | 1.243–1.439 | 0.000 |
T | 0.000 | 0.000 | ||||
T0/T1 | Reference | Reference | ||||
T2 | 1.827 | 1.742–1.917 | 0.000 | 1.431 | 1.360–1.505 | 0.000 |
T3 | 3.151 | 2.906–3.416 | 0.000 | 1.904 | 1.745–2.077 | 0.000 |
T4 | 4.664 | 4.260–5.108 | 0.000 | 2.343 | 2.123–2.585 | 0.000 |
N | 0.000 | 0.000 | ||||
N0 | Reference | Reference | ||||
N1 | 1.556 | 1.479–1.636 | 0.000 | 1.381 | 1.311–1.456 | 0.000 |
N2 | 2.893 | 2.690–3.110 | 0.000 | 2.103 | 1.945–2.273 | 0.000 |
N3 | 4.649 | 4.260–5.074 | 0.000 | 3.312 | 3.011–3.642 | 0.000 |
ER | 0.000 | 0.000 | ||||
Negative | Reference | Reference | ||||
Positive/Borderline | 0.686 | 0.652–0.722 | 0.000 | 0.817 | 0.762–0.877 | 0.000 |
PR | 0.000 | 0.000 | ||||
Negative | Reference | Reference | ||||
Positive/Borderline | 0.704 | 0.673–0.736 | 0.000 | 0.854 | 0.805–0.906 | 0.000 |
Chemotherapy | 0.000 | 0.000 | ||||
No/Unknown | Reference | Reference | ||||
Yes | 0.803 | 0.754–0.855 | 0.000 | 1.454 | 1.358–1.558 | 0.000 |