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Table 2 Association between ln(α-Klotho) and frailty

From: L-shaped association of serum α-Klotho and frailty among the middle-aged and older adults: results from NHANES 2007–2016

 

Model 1

 

Model 2

 

Model 3

ORs (95%CI)

P-value

 

ORs (95%CI)

P-value

 

ORs (95%CI)

P-value

ln(α-Klotho)

0.73 (0.59, 0.90)

0.005*

 

0.63 (0.51, 0.79)

< 0.001*

 

0.63 (0.50, 0.79)

< 0.001*

Total

        

 Q1

1 (ref)

  

1 (ref)

  

1 (ref)

 

 Q2

0.73 (0.60, 0.89)

0.002*

 

0.71 (0.58, 0.87)

0.001*

 

0.74 (0.59, 0.93)

0.01*

 Q3

0.73 (0.59, 0.90)

0.004*

 

0.69 (0.56, 0.86)

0.001*

 

0.72 (0.57, 0.91)

0.01*

 Q4

0.79 (0.66, 0.95)

0.01*

 

0.71 (0.58, 0.86)

< 0.001*

 

0.71 (0.57, 0.87)

0.002*

P for Trend

 

0.01*

  

< 0.001*

  

< 0.001*

  1. Note 2: ORs = odds ratio; CI = confidence interval; Q1 (≤ 6.464), Q2 (6.464, 6.667), Q3 (6.667, 6.881), Q4 (> 6.881); No covariable was adjusted in Model 1. Model 2 was adjusted for sex, age, and race/ethnicity and Model 3 for all covariates from Table 1 except frailty and number
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