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Table 2 Comparison of basic clinical data, motor symptoms and NMS of PD patients with or without sarcopenia

From: Sarcopenia is associated with non-motor symptoms in Han Chinese patients with Parkinson's Disease: a cross-sectional study

Variable

Without Sarcopenia

With Sarcopenia

t/x2/z

P-Value

Power (%)

(n = 90)

(n = 33)

Age,y

63.37 ± 8.99

72.18 ± 7.12

-4.209

 < 0.001

10.0

Disease duration,y

4(2,7)

6(3,9.5)

-1.772

0.076

50.6

Education background,y

7.5(4.75,9)

6(2,9.5)

-0.460

0.646

37.5

Male, n(%)

45(50)

11(33.3)

2.705

0.100

37.6

Hypertension, n(%)

27(30)

7(21.2)

0.932

0.334

16.2

Type 2 diabetes, n(%)

11(12.2)

2(6.1)

 

0.551

16.6

Smoker, n(%)

20(22.2)

4(12.1)

1.569

0.210

24.0

Alcohol user, n(%)

17(18.9)

4(12.1)

0.781

0.377

14.3

Tea or coffee user, n(%)

25(27.8)

8(24.2)

0.154

0.695

6.7

Types of Motor Symptoms

  

0.795

0.672

11.5

Tremor-dominant, n(%)

28(31.1)

8(24.2)

   

PIGD-dominant, n(%)

50(55.6)

19(57.6)

   

Mixed, n(%)

12(13.3)

6(18.2)

   

state of nutrition

  

7.291

0.007

97.4

no risk of malnutrition, n(%)

52(57.8)

6(18.2)

   

Risk of malnutrition, n(%)

38(42.2)

27(81.8)

   

BMI (kg/m2)

24.74 ± 2.72

20.64 ± 2.96

7.225

 < 0.001

100

ASM (kg/m2)

7.36(6.38,7.89)

5.5(5.18,6.66)

-6.336

 < 0.001

100

Grip strength (kg)

24.9(18.7,32.63)

18.7(15.3,22.05)

-4.167

 < 0.001

73

6 m GS (s)

7.04(5.99,8.33)

7.75(7.15,9.43)

-2.934

0.003

36.6

UPDRS-I

3(2,5)

4(2.5,6)

-2.056

0.040

39.8

UPDRS-II

11(8,16.25)

15(9,22.5)

-2.501

0.012

59.1

UPDRS-III

24(15,33)

26(13.5,33)

-0.231

0.817

8.9

UPDRS-IV

1(0,3)

2(0.5,6)

-2.793

0.005

29.8

Dyskinesia, n(%)

11(12.2)

6(18.2)

0.72

0.396

13.6

MF, n(%)

20(22.2)

13(39.4)

3.627

0.057

47.8

H-Y early stage, n(%)

71(78.9)

20(60.6)

4.193

0.041

53.5

LED (mg/d)

387.5(225, 654.75)

499(293.75,724)

-1.369

0.171

28.1

MMSE

26(23,28)

23(19.5,27)

-2.446

0.014

84.2

PSQI

8(5.75,11)

13(10,15.5)

-4.693

 < 0.001

99.2

ESS

4(3,9)

7(3,12.5)

-1.891

0.059

63.0

FSS

39.5(27.75,48.25)

49(43.5,53.5)

-3.815

 < 0.001

75.0

HAMA

8(5,13)

16(10.5,21)

-4.328

 < 0.001

99.9

HAMD

9(6,13.25)

17(12.5,22.5)

-4.157

 < 0.001

99.9

NMSQ

8(5,12.25)

12(8,17)

-3.383

0.001

78.9

SCOPA-AUT

10(6,14)

15(10.5, 19.5)

-3.297

0.001

89.6

PDQ-8

8.5 ± 4.81

12.39 ± 5.57

-3.81

 < 0.001

98.5

ADLs

24(21,35)

37(25.5,56)

-3.753

 < 0.001

99.9

  1. Values in bold are significant at P < 0.05
  2. Data were expressed as n (%), mean ± SD, median (interquartile range). P values are from Student’ s t-test or the Mann–Whitney U-test or Chi-square tests or Fisher’s exact test
  3. Abbreviations: PD Parkinson's disease, PIGD postural instability and gait difficulty, BMI Body Mass Index, ASM appendicular skeletal mass, 6 m GS 6-m gait speed, UPDRS Unified Parkinson's Disease Rating Scale, MF motor fluctuations, LED Levodopa Equivalent Dose, MMSE Mini Mental State Scale, PSQI Pittsburgh Sleep Quality Index, ESS Epworth Sleep Scale, FSS Fatigue Severity Scale, HAMA Hamilton Anxiety Scale, HAMD Hamilton Depression Scale, NMSQ Non-Motor Symptom Questionnaire, SCOPA-AUT Scales for Outcomes in Parkinson's Disease-Autonomic questionnaire, PDQ-8 Parkinson's Disease Quality of Life Scale-8, ADLs Ability of Daily Living scale