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Table 3 Risk factors associated with death(FI-Lab as continuous variables)

From: Prognostic significance of frailty in hospitalized elderly patients with community-acquired pneumonia: a retrospective cohort study

variable

Univariable HR (95% CI)

p value

Multivariable HR (95% CI)

p value

Age(years)

1.07(1.06–1.08)

 < 0.001

1.04(1.02–1.06)

 < 0.001

Male Sex(vs female)

1.49(1.20–1.83)

 < 0.001

1.03(0.71–1.48)

0.877

BMI(kg/m2)

0.94(0.91–0.97)

 < 0.001

0.95(0.91–0.99)

0.011

Smoker (vs nonsmoker)

0.90(0.71–1.12)

0.337

  

Drinking (vs no)

0.65(0.47–0.91)

0.012

0.55(0.29–1.04)

0.067

WBC(× 10^9/L)

1.07(1.06–1.09)

 < 0.001

0.61(0.40–0.93)

0.022

LYMPH(× 10^9/L)

0.55(0.45–0.66)

 < 0.001

1.97(1.07–3.63)

0.009

NEUT(× 10^9/L)

1.09(1.07–1.11)

 < 0.001

1.72(1.11–2.65)

0.014

eGFR(ml/min)

0.99(0.98–0.99)

 < 0.001

1.01(1.00–1.01)

0.084

CRP(mg/L)

1.01(1.00–1.01)

 < 0.001

1.00(0.99–1.00)

0.134

PCT(ng/ml)

1.03(1.02–1.04)

 < 0.001

1.00(0.97–1.01)

0.248

aCCI

1.31(1.26–1.35)

 < 0.001

1.13(1.05–1.21)

 < 0.001

CURB-65

2.25(1.99–2.54)

 < 0.001

1.29(1.01–1.64)

0.043

FI-Lab, continuous variablesa

1.89(1.73–2.01)

 < 0.001

1.58(1.36–1.83)

 < 0.001

  1. Abbreviations BMI Body mass index, WBC White blood cell, NEUT Neutrophil, LYMPH Lymphocyte, eGFR estimated glomerular filtration rate, hs-CRP high sensitivity C-reactive protein, PCT Procalcitonin, CURB-65 Confusion, blood Urea nitrogen, Respiratory rate, systolic or diastolic Blood pressure, and Age > 65, LOS length of stay during hospitalization
  2. aA change in FI-Laboratory represents a 0.10 increase