Table 2 Risk factors associated with death(FI-Lab as categorical variable)
variable | Univariable HR (95% CI) | p value | Multivariable HR (95% CI) | p value |
|---|---|---|---|---|
Age(years) | 1.01(1.00–1.21) | 0.116 | ||
Male Sex(vs female) | 0.97(0.88–1.07) | 0.532 | ||
BMI(kg/m2) | 0.80(0.78–0.83) | < 0.001 | 0.85(0.82–0.88) | < 0.001 |
Smoker (vs nonsmoker) | 0.90(0.72–1.12) | 0.341 | ||
Drinking (vs no) | 1.24(1.05–1.46) | 0.012 | ||
WBC(× 10^9/L) | 1.07(1.05–1.09) | < 0.001 | ||
LYMPH(× 10^9/L) | 0.55(0.46–0.67) | < 0.001 | ||
NEUT(× 10^9/L) | 1.09(1.07–1.11) | < 0.001 | 1.05(1.02–1.07) | < 0.001 |
eGFR(ml/min) | 0.99(0.99–0.99) | < 0.001 | 1.01(1.00–1.01) | < 0.001 |
CRP(mg/L) | 1.01(1.00–1.01) | < 0.001 | ||
PCT(ng/ml) | 1.03(1.02–1.04) | < 0.001 | ||
aCCI | 1.30(1.26–1.35) | < 0.001 | 1.17(1.12–1.23) | < 0.001 |
CURB-65 | 2.23(1.98–2.53) | < 0.001 | 1.51(1.30–1.75) | < 0.001 |
FI-Lab, categorical variable | ||||
Robust | 1 | 1 | ||
Pre-frail | 2.86(1.90–4.30) | < 0.001 | 2.02(1.35–3.05) | 0.001 |
Frail | 6.81(4.64–10.00) | < 0.001 | 3.61(2.41–5.40) | < 0.001 |