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Table 3 Main trial characteristics of RCTs including majority of older people

From: Temporal changes in characteristics and external validity of randomized controlled trials in older people from 2012 to 2019

 

2012

 

2019

(N = 300)

(N = 363)

Number of participants, N (median IQR)

114 (47–288)

 

104 (58–240)

Age of participants, years (median, IQR)

66 (63–70)

 

66 (63–70)

Disease categories, N (%)

 Circulatory

74 (25)

Circulatory

75 (21)

 Neoplasms

56 (19)

Neoplasms

66 (18)

 Musculoskeletal

28 (9)

Musculoskeletal

51(14)

 Nervous

13 (8)

Metabolic

30 (8)

 Digestive

19 (6)

Respiratory

24 (7)

 Other

100 (33)

Other

117 (32)

  1. Trials were classified as including a majority of older people if mean trial participant age ≥ 60 years
  2. Medians, interquartile ranges (difference between 25 and 75th percentile) and percentages are reported
  3. For trials from both 2012 and 2019, the number of trials in the five most classified disease categories are shown
  4. Abbreviations: RCT Randomized controlled trial, IQR Interquartile range