Table 3 Multivariable regression of depressive symptoms and subsequent cognitive function decline

Model 0: Dep-S(2003)

-0.012^**

1.07

-0.012^‡

1.04

-0.012^*

1.07

R² = 0.26, Adj. R² = 0.25

R² = 0.14, Adj. R² = 0.13

R² = 0.32, Adj. R² = 0.32

Model 1: Dep-S(2003)

-0.010(16.67%)

1.09

-0.011(8.33%)

1.05

-0.0091(24.17%)

1.09

PA(2003)

-0.010

1.33

-0.0052

1.39

-0.018

1.29

PA(2007)

0.040^*

1.28

0.029

1.32

-0.040

1.25

R² = 0.26, Adj. R² = 0.26

R² = 0.13, Adj. R² = 0.13

R² = 0.32, Adj. R² = 0.32

Model 2: Dep-S(2003)

-0.0080(33.33%)

1.09

-0.0085(28.14%)

1.06

-0.0070(40.06%)

1.09

Int-LA(2003)

0.046^*

1.65

0.038

1.48

0.043

1.69

Int-LA(2007)

0.13^***

1.44

0.12^**

1.30

0.13^*

1.49

R² = 0.27, Adj. R² = 0.27

R² = 0.14, Adj. R² = 0.14

R² = 0.33, Adj. R² = 0.32

Model 3: Dep-S(2003)

-0.0096^*(20.00%)

1.10

-0.0099(15.85%)

1.06

-0.0085 (27.50%)

1.09

Phy-LA(2003)

0.018

1.37

0.027

1.36

-0.0023

1.38

Phy-LA(2007)

0.084^**

1.37

0.088^*

1.36

0.088

1.38

R² = 0.26, Adj. R2 = 0.26

R² = 0.14, Adj. R² = 0.13

R² = 0.33, Adj. R² = 0.32

Model 4: Dep-S(2003)

-0.011^*(8.33%)

1.09

-0.011(6.10%)

1.06

-0.0096(18.17%)

1.09

Soc-LA(2003)

0.037

1.10

-0.0050

1.17

-0.035

1.04

Soc-LA(2007)

0.065

1.07

0.10

1.12

0.043

1.06

R² = 0.26, Adj. R² = 0.26

R² = 0.13, Adj. R² = 0.13

R² = 0.32, Adj. R² = 0.32

Model 5: Dep-S(2003)

-0.0099^*(17.50%)

1.08

-0.012(1.69%)

1.05

-0.0079(33.28%)

1.08

Gar-LA(2003)

0.037

1.20

-0.038

1.21

0.10

1.21

Gar-LA(2007)

0.12^*

1.21

0.073

1.20

0.145^*

1.21

R² = 0.26, Adj. R² = 0.26

R² = 0.13, Adj. R² = 0.13

R² = 0.33, Adj. R² = 0.32

Model 6: Dep-scores(2003)

0.00072(-)

1.19

-0.0033(71.95%)

1.13

0.0029(NA)

1.20

Mo-function(2003)

-0.015

1.76

-0.0072

1.63

-0.016

1.77

Mo-function(2007)

-0.051^***

1.78

-0.054^***

1.63

-0.044^***

1.79

R² = 0.29, Adj. R² = 0.28

R² = 0.16, Adj. R² = 0.15

R² = 0.34, Adj. R² = 0.34